Skip to main content
SpringerLink
Log in
Book cover

Ergebnisse der Inneren Medizin und Kinderheilkunde / Advances in Internal Medicine and Pediatrics pp 1–75Cite as

Alcohol and the Gastrointestinal Tract

  • Conference paper

Abstract

Alcohol related diseases have become one of the major medical and social problems in many countries with a high standard of living Schmidt and Popham 1975, 1976). While alcohol has been known for a long time to influence gastric secretion and excessive alcohol intake has been assummed to cause mucosal injury of the stomach, the effects of alcohol and alcoholism on other parts of the gastrointestinal tract have received intensive study only in the past 10–15 years. The purpose of the present review is to report mainly on the progress made during the past decade in clarifying metabolic and toxic effects of alcohol on the gastrointestinal tract. No attempt will be made to review the older literature exhaustively, since the major steps in the development of this field until the early sixties have been summarized in several reviews Beazell and Ivey 1940; Chey 1972; Kalant 1971; Saint-Blanquat and Derache 1972; Schmidt-Wilcke and Martini 1975).

Original studies described in this review were supported, in part, by the Deutsche Forschungsgemeinschaft, grant Bo334/5–8 In this paper alcohol and ethanol are used interchangeable

This is a preview of subscription content, log in via an institution.

Chapter
USD   29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD   44.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD   59.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Learn about institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  • Adler HF, Bearell JM, Atkinson AJ, Ivy AC (1941) The motor response of colon to alcohol. J Stud Alcohol 10: 638

    Google Scholar 

  • Althausen TL, Uyeyama K, Loran MR (1960) Effects of alcohol on absorption of vitamin A in normal and gastrectomized subjects. Gastroenterology 38: 942

    PubMed  CAS  Google Scholar 

  • Antonson DL, Barak AJ, Vanderhoff JA (1978) Effects of acute and chronic ethanol ingestion on zinc absorption. Clin Res 26: 660

    Google Scholar 

  • Astaldi G, Strosselli E (1960) Peroral biopsy of the intestinal mucosa in hepatic cirrhosis. Am J Dig Dis 5: 603

    PubMed  CAS  Google Scholar 

  • Augur NA (1970) Gastric mucosal blood flow following damage by ethanol, acetic acid, or aspirin. Gastroenterology 58: 311

    PubMed  CAS  Google Scholar 

  • Aznar-Reig A, Herrera Justiniano E, Rodriguez de Quesada B, Diaz Calvez M, López Fernéndez M (1973) Absorción intestinal de calcio 47 en la cirrhosis hepética. Rev Clin Esp 128: 467

    PubMed  CAS  Google Scholar 

  • Balaghi M, Neal RA (1977) Effect of chronic ethanol administration on thiamin metabolism in the rat. J Nutr 107: 2144

    PubMed  CAS  Google Scholar 

  • Barak AJ, Beckenhauer HC, Kerrigan FJ (1967) Zinc and manganese levels in serum and liver after alcohol feeding and development of fatty cirrhosis in rats. Gut 8: 454

    PubMed  CAS  Google Scholar 

  • Baraona E, Lieber CS (1975) Intestinal lymph formation and fat absorption: stimulation by acute ethanol administration and inhibition by chronic ethanol feeding. Gastroenterology 68: 495

    PubMed  CAS  Google Scholar 

  • Baraona E, Pirola RC, Lieber CS (1974) Small intestinal damage and changes in cell population produced by ethanol ingestion in the rat. Gastroenterology 66: 226

    CAS  Google Scholar 

  • Baraona E, Pirola RC, Lieber CS (1975) Acute and chronic effects of ethanol on intestinal lipid metabolism. Biochim Biophys Acta 388: 19

    PubMed  CAS  Google Scholar 

  • Barboriak JJ, Meade RC (1969) Impairment of gastrointestinal processing of fat and protein by ethanol in rats. J Nutr 98: 373

    PubMed  CAS  Google Scholar 

  • Barboriak JJ, Meade RC (1970) Effect of alcohol on gastric emptying in man. Am J Clin Nutr 23: 1151

    PubMed  CAS  Google Scholar 

  • Bargielska A, Kosmowska B, Panowicz H, Woyke M (1968) The influence of ethanol on alkaline phosphatase activity in the small intestine in rats. Patol Pol 6: 483

    Google Scholar 

  • Baskind AF, Berry AV Hamilton DG, Bremner CG (1978) Detection of early oesophageal cancer and reflux oesophagistis in Southern African blacks. Digestion 16: 229

    Google Scholar 

  • Beazell JM, Ivey AC (1940) The influence of alcohol on the digestive tract. J Stud Alcohol 1: 45

    CAS  Google Scholar 

  • Berggren SM, Goldberg L (1940) The absorption of ethyl alcohol from the gastrointestinal tract as a diffusion process. Acta Physiol Scand 1: 246

    CAS  Google Scholar 

  • Bernard A, Delattre A, Lamelin P (1964) Le macanisme d’action de l’alcool sur la muqueuse gastrique: sa propriété hygroscopique et deshydratande. Acta Gastroenterol Belg 27: 129

    PubMed  CAS  Google Scholar 

  • Bernstein IM, Webster KH, Williams RC, Strickland RG (1974) Reduction in circulating T-lymphocytes in alcoholic liver disease. Lancer II: 488

    Google Scholar 

  • Bianchi A, Chipman DW, Dreskin A, Rosensweig NS (1970) Nutritional folic acid deficiency with megaloblastic changes in the small-bowel epithelium. N Engl J Med 282: 859

    PubMed  CAS  Google Scholar 

  • Bieck PR (1976) The role of cyclic nucleotides in gastric acid secretion. In: Case RM, Goebell H (eds) Stimulus-secretion coupling in the gastrointestinal tract. MTP Press, Lancaster, p 129

    Google Scholar 

  • Biggerstaff RJ, Leitch GJ (1977) Effects of ethanol on electrical parameters of the in vivo rat stomach. Am J Dig Dis 22: 1064

    PubMed  CAS  Google Scholar 

  • Bingham JR (1960) Precipitating factors in peptic ulcer. Cn Med Assoc J 83: 205

    CAS  Google Scholar 

  • Bischoff A (1971) Die alkoholische Polyneuropathie. Dtsch Med Wochenschr 96: 317

    PubMed  CAS  Google Scholar 

  • Bloom SR, Patel HR, Johnston DI (1976) Failure of secretin release in coeliac disease. Gut 17: 812

    Google Scholar 

  • Bode C, Knüppel H, Dürr HK, Bode JCh (to be published) Changes in enzyme activities in the jejunal mucosa of chronic alcoholics. Z Gastroenterol

    Google Scholar 

  • Bode JCh (1978) The metabolism of alcohol: physiological and pathophysiological aspect. J R Coll Physicians Lond 12: 122

    PubMed  CAS  Google Scholar 

  • Bode JCh (to be published) Alcoholhepatitis und Alkoholzirrhose — Klinik, Begleiterkrankungen und Therapie. In: Bode JCh, Eckert P, Fischer M, Zelder O (eds) Leberversagen. Thieme, Stuttgart

    Google Scholar 

  • Bode JCh, Thiele D (1975) Hemmung des Äthanolabbaus beim Menschen durch Fasten: Reversibilität durch Fructose-Infusion. Dtsch Med Wochenschr 100: 1849

    PubMed  CAS  Google Scholar 

  • Bode JCh, Goebell H, Stahler M (1970) Änderungen der Alkoholdehydrogenase-Aktivität in der Rattenleber durch Eiweißmangel und Äthanol. Z Gesamte Exp Med 152: 111

    PubMed  CAS  Google Scholar 

  • Bode JCh, Buchwald B, Goebell H (1971) Hemmung des Äthanolabbaues durch Proteinmangel beim Menschen. Dtsch Med Wochenschr 40: 1576

    Google Scholar 

  • Bode JCh, Wöltge E, Kahm O, Korb G (1976) Leberschäden bei chronischen Alkoholikern mit und ohne Delirium tremens. Dtsch Med Wochenschr 101: 1081

    PubMed  CAS  Google Scholar 

  • Bode JCh, Knüppel H, Schwerk W, Dürr HK, Lorenz-Meyer H (to be published) Morphometry studies on the jejunal mucosa in chronic alcoholics. Scand J Gastroenterol

    Google Scholar 

  • Bode JCh, Heidelbach R, Mannheim W, Bode Ch, Martini GA (to be published) Bacterial ecology in the jejunum of chronic alcoholics

    Google Scholar 

  • Bodin F, Delage Y, Lichtenstein H, Denez B, Conte M (1977) Le syndrome de Mallory-Weiss. Gastroenterol Clin Biol 1: 637

    PubMed  CAS  Google Scholar 

  • Bo-Linn GW, Shanbour LL (1977) Effects of antral ethanol on gastric acid secretion, potential difference and serum gastrin. Proc Soc Exp Biol Med 155: 594

    PubMed  CAS  Google Scholar 

  • Bordalo O, Noronha M, Lamy J, Dreiling DA (1975) Standard and augmented secretin testing in chronic pancreatic alcoholic disease. Am J Gastroenterol 64: 125

    PubMed  CAS  Google Scholar 

  • Bouchier IAD, Williams HS (1969) Determination of fecal blood loss after combined alcohol and soidum-acetylsalicylate intake. Lancet I: 178

    Google Scholar 

  • Bouquillon M (1976) Effects of acute ethanol ingestion on fat absorption. Lipids 11: 848

    Google Scholar 

  • Brasitus TA, Field M, Kimberg DV (1976) Intestinal mucosal cyclic GMP: regulation and relation to ion transport. Am J Physiol 231: 275

    PubMed  CAS  Google Scholar 

  • Brassinne A (1979) Effects of ethanol on plasma protein shedding in the human stomach. Am J Dig Dis 24: 44

    CAS  Google Scholar 

  • Brayton RG, Stokes PE, Schwartz MS, Louria DB (1970) Effect of alcohol and various diseases on leukocyte mobilization, phagocytosis and intracellular bacterial killing. N Engl J Med 282: 123

    PubMed  CAS  Google Scholar 

  • Bretholz A, Levesque D, Voirol M, Tiscoria OM, Bloom SR, Sarles H (1978) Impaired secretin release in chronic alcoholic dogs. Digestion 17: 437

    PubMed  CAS  Google Scholar 

  • Broitman SA, Small MD, Vitale JJ, Zamcheck N (1961) Intestinal absorption and urinary excretion of xylose in rats fed reduced protein and thyroxine or alcohol. Gastroenterology 41: 21

    Google Scholar 

  • Broitman SA, Gottlieb LS, Vitale JJ (1976) Augmentation of ethanol absorption by mono-and disaccharides. Gastroenterology 70: 1101

    PubMed  CAS  Google Scholar 

  • Bungert H-J (1978) Absorption of hemoglobin and hemoglobin iron in alcohol-induced liver injury. Digestion 9: 293

    Google Scholar 

  • Carter EA, Isselbacher KJ (1971) The metabolism of ethanol to carbon dioxide by stomach and small intestinal slices. Proc Soc Exp Biol Med 138: 817

    PubMed  CAS  Google Scholar 

  • Carter EA, Isselbacher KJ (1973) Effect of ethanol on intestinal adenosine triphosphate (ATP) content. Proc Soc Exp Biol Med 142: 1171

    PubMed  CAS  Google Scholar 

  • Carter EA, Drummey GD, Isselbacher KJ (1971) Ethanol stimulates triglyceride synthesis by the intestine. Science 174: 1245

    PubMed  CAS  Google Scholar 

  • Caspary WF (1972) On the mechanism of D-xylose absorption from the intestine. Gastroenterology 63: 531

    PubMed  CAS  Google Scholar 

  • Caspary WF (1975) Einfluß von Aspirin, Antacida, Alkohol und Gallensäuren auf die transmurale elektrische Potentialdifferenz des menschlichen Magens. Dtsch Med Wochenschr 100: 1263

    PubMed  CAS  Google Scholar 

  • Castell DO, Harris LD (1970) Hormonal control of gastroesophageal sphincter strength. N Engl J Med 282: 886

    PubMed  CAS  Google Scholar 

  • Chang T, Lewis J, Glaszko AJ (1967) Effects of ethanol and other alcohols on transport of amino acids and glucose by everted sacs and small rat intestine. Biochim Biophys Acta 135: 1000

    PubMed  CAS  Google Scholar 

  • Chang T, Glazko AJ (1975) Effect of ehtanol on intestinal amino acid transport. In: Rothschild MA, Oraz M, Schreiber SS (eds) Alcohol and abnormal protein biosynthesis. Pergamon Press, New York, p 95

    Google Scholar 

  • Charlton RW, Jacobs P, Seftel H, Bothwell TH (1964) Effect of alcohol on iron absorption. Br Med J II: 1427

    Google Scholar 

  • Cherrick GR, Baker H, Frank O, Leevy CM (1965) Observations on hepatic avidity for folate in Laennec’s cirrhosis. J Lab Clin Med 66: 446

    PubMed  CAS  Google Scholar 

  • Chey WY (1972) Alcohol and gastric mucosa. Digestion 7: 239

    PubMed  CAS  Google Scholar 

  • Chey WY, Kusakcioglu O, Dinoso V, Lorber SH (1968) Gastric secretion in patients with chronic pancreatitis and in chronic alcoholics. Arch Intern Med 122: 399

    PubMed  CAS  Google Scholar 

  • Chey WY, Kosay S, Lorber SH (1972) Effects of chronic administration of ethanol on gastric secretion of acid in dogs. Am J Dig Dis 17: 153

    PubMed  CAS  Google Scholar 

  • Chin JH, Goldstein DB (1976) Drug tolerance in biomembranes: a spin label study of the effects of ethanol. Science 196: 684

    Google Scholar 

  • Chin JH, Goldstein DB (1977) Effects of low concentrations of ethanol on the fluidity of spin-labeled erythrocyte and brain membranes. Mol Pharmacol 13: 435

    PubMed  CAS  Google Scholar 

  • Chittenden RH, Mendel LB, Jackson HC (1898) A further study of the influence of alcohol and alcoholic drinks upon digestion with special references to secretion. Am J Physiol I: 164

    Google Scholar 

  • Cho KJ, Hunter TB, Whitehouse WM (1975) The columnar-epithelial-lined lower esophagus and its association with adenocarcinoma of the esophagus. Radiology 115: 563

    PubMed  CAS  Google Scholar 

  • Chowdhury AR, Malmud LS, Dinoso VP (1977) Gastrointestinal plasma protein loss during ethanol ingestion. Gastroenterology 72: 37

    PubMed  CAS  Google Scholar 

  • Chung RSK, Johnson GM, Denbesten L (1977) Effect of sodium taurocholate and ethanol on hydrogen ion absorption in rabbit esophagus. Am J Dig Dis 22: 582

    PubMed  CAS  Google Scholar 

  • Cooke AR (1978) Drug damage to the gastroduodenum. In: Sleisinger MH, Fordtran JS (eds) Gastrointestinal disease, 2nd edn. Saunders, Philadelphia, p 807

    Google Scholar 

  • Cooke AR, Birchall A (1969) Absorption of the ethanol from the stomach. Gastroenterology 57: 269

    PubMed  CAS  Google Scholar 

  • Cornet A, Hartmann L, Courtois J-E, Dubrisay J, Demelier J-F, Barbier JPh, Renault P, Carnot F, Debetz J, Dadoune J-P (1978) Cirrhose due foie et intestin grêle. Confrontations cliniques, biologiques, histologiques, immunologiques et bactériologiques. Sem Hop Paris 49: 1639

    Google Scholar 

  • Dagradi AE, Lee ER, Brosco DL, Stempien StJ (1973) The clinical spectrum of hemorrhagic erosive gastritis. Am J Gastroenterol 60: 30

    PubMed  CAS  Google Scholar 

  • Dahlquist A, Lindquist B (1971) Lactose intolerance and protein malnutrition. Acta Paediatr Scand 60: 488

    Google Scholar 

  • Davenport HW (1967) Ethanol damage to canine glandular mucosa. Proc Soc Exp Biol 126: 657

    CAS  Google Scholar 

  • Davenport HW (1969) Gastric mucosal hemorrhage in dogs, effects of acid, aspirin and alcohol. Gastroenterology 56: 439-449

    PubMed  CAS  Google Scholar 

  • Davenport HW (1974) Plasma protein shedding by the canine oxyntic glandular mucosa induced by topical application of snake venoms and ethanol. Gastroenterology 67: 264

    PubMed  CAS  Google Scholar 

  • Daves IA, Miller JH, Lemmi CAE, Thompson JC (1965) Mechanism and inhibition of alcohol stimulated gastric secretion. Surg Forum 16: 305

    PubMed  CAS  Google Scholar 

  • Dawson DC, Cooke AR (1978) Parallel pathways for ion transport across rat gastric mucosa: effect of ethanol. Am J Physiol 235: E7-19

    Google Scholar 

  • Debray C, Hardouin J-P, Laumonier R, Housset P, Helie J-P, Martin E (1957) La gastrite éthylique sous le controle de la gastrobiopsie. Arch Fr Mai App Dig 46: 925

    CAS  Google Scholar 

  • Denis P, Galmiche J-P, Benozio M, Accary J-P, Colin R, Pasquis P, Lefrançois R, Geffroy Y (1978) Reflux gastro-oesophagien et cirrhose alcoolique. Gastroenterol Clin Biol 2: 263

    PubMed  CAS  Google Scholar 

  • Dhar DJ, Selhub J, Gay C, Rosenberg I (1966) Characterization of the individual components of intestinal folate transport. Gastroenterology 72: 1049

    Google Scholar 

  • Dilawari JB, Edwards DAW, Grimes DH (1974) The probability of symptoms or radiographic evidence of reflux predicted by lower esophageal sphincter pressure. In: Daniel EE (ed) Proc. IVTH Int. Sympos. Gastrointestinal Motility. Mitchell Press, Vancouver, p 441

    Google Scholar 

  • Dinda PK, Beck IT (1977) On the mechanism of the inhibitory effect of ethanol on intestinal glucose and water absorption. Am J Dig Dis 22: 529

    PubMed  CAS  Google Scholar 

  • Dinda PK, Beck IT, Beck M, McElligott TF (1975) Effect of ethanol on sodium-dependent glucose transport in the small intestine of the hamster. Gastroenterology 68: 1517

    PubMed  CAS  Google Scholar 

  • Dinoso VP, Chey WY, Siplet H (1970) Effects of ethanol on the gastric mucosa of the Heidenhain pouch of dogs. Am J Dig Dis 15: 809

    PubMed  CAS  Google Scholar 

  • Dinoso VP, Meshkinpour H, Lorber SH (1972a) Studies on the acute effects of ethanol on the gastric mucosa in man. Gastroenterology 62: 843

    Google Scholar 

  • Dinoso VP, Chey WY, Braverman SP, Rosen AP, Ottenberg D, Lorber SH (1972b) Gastric secretion and gastric mucosal morphology in chronic alcoholics. Arch Intern Med 130: 715

    PubMed  Google Scholar 

  • Dinoso VP, Chuang J, Murthy SNS (1976) Changes in mucosal and venous histamine concentrations during instillation of ethanol in the canine stomach. Am J Dig Dis 21: 93

    PubMed  CAS  Google Scholar 

  • Dinoso VP, Ming SC, McNiff J (1976) Ultrastructural changes of the canine gastric mucosa after topical application of graded concentrations of ethanol. Am J Dig Dis 21: 626

    PubMed  CAS  Google Scholar 

  • Dormanns E (1940) Das Ösophaguscarcinom: Ergebnisse der unter Mitarbeit von 39 Pathologischen Instituten Deutschlands durchgeführten Erhebung über das Ösophaguscarcinom (1925–1933). Z Krebsforsch 49: 86

    Google Scholar 

  • Dragstedt CA, Gray JS, Lawton AH, Ramirez de Abellano M (1940) Does alcohol stimulate gastric secretion by liberating histamine? Proc Soc Exp Biol Med 43: 26

    CAS  Google Scholar 

  • Dürr HK, Bode JCh, Gieseking R, Haase R, v. Arnim I, Beckmann B (1975) Ånderungen der exokrinen Funktion der Glandula parotis und des Pankreas bei Patienten mit Leberzirrhose und chronischem Alkoholismus. Verh Dtsch Ges Inn Med 81: 1322

    PubMed  Google Scholar 

  • Dumke K, Grosse G, Niedobitek F, Schmid E (1975) Tierexperimentelle Untersuchungen zur kombinierten ulzerogenen Wirkung von Alkohol und Streß bei der Ratte. Z Gastroenterol 2: 334

    Google Scholar 

  • Eastwood GL, Erdmann KR (1978) Effect of ethanol on canine gastric epithelial ultrastructure and transmucosal potential difference. Am J Dig Dis 23: 429

    PubMed  CAS  Google Scholar 

  • Eastwood GL, Kirchner JP (1974) Changes in the fine structure of mouse gastric epithelium produced by ethanol and urea. Gastroenterology 67: 71

    PubMed  CAS  Google Scholar 

  • Eichner ER, Hillmar RS (1971) The evolution of anemia in alcoholic patients. Am J Med 50: 218

    PubMed  CAS  Google Scholar 

  • Elbel H, Schleyer F (1956) Blutalkohol. Thieme, Stuttgart

    Google Scholar 

  • Elmslie RG, Davis RA, Magee DF, White TT (1965) Absorption of alcohol after gastrectomy. Surg Gynecol Obstet 119: 1256

    Google Scholar 

  • Elwin CE (1969) Some factors influencing the stimulatory effect of ethanol on gastric acid secretion during antrum application. Acta Physiol Scand 75: 12

    PubMed  CAS  Google Scholar 

  • Faris AA, Reyes MG (1971) Reappraisal of alcoholic myopathy. J Neurol Neurosurg Psychiatry 34: 86

    PubMed  CAS  Google Scholar 

  • Fast BB, Wolfe StJ, Stomont JM, Davidson ChS (1959) Fat absorption in alcoholics with cirrhosis. Gastroenterology 37: 321

    PubMed  CAS  Google Scholar 

  • Field M, Brasitus TA, Sheerin HE, Kimberg DV (1976) The role of cyclic nucleotides in the regulation of intestinal ion transport. In: Case RM, Goebell H (eds) Stimulus secretion coupling in the gastrointestinal tract. MTP Press, Lancaster?, p 387

    Google Scholar 

  • Filippini L, Löftier A (1972) Exokrine Pankreasfunktion bei chronischem Alkoholkonsum. Dtsch Med Wochenschr 97: 596

    PubMed  CAS  Google Scholar 

  • Fischer RA, Ellison CW, Thayer WR, Spiro HM, Glaser GH (1965) Esophageal motility in neuromuscular disorders. Ann Intern Med 63: 220

    Google Scholar 

  • Fisher JM, Mackay JR, Taylor KB, Ungar B (1967) An immunological study of categories of gastritis. Lancet I: 176

    Google Scholar 

  • Flink EB (1971) Mineral metabolism in alcoholism. In: Kissen B, Begleiter H (eds) The biology of alcoholism. Plenum Press, New York, p 377

    Google Scholar 

  • Flores J, Sharp GW (1976) Studies on the stimulation of adenylate cyclase by cholera toxin. In: Case RM, Goebell H (eds) Stimulus secretion coupling in the gastrointestinal tract. MTP Press, Lancaster, p 331

    Google Scholar 

  • Forshae J, Moohouse EH, Harwood L (1964) Megaloblastic anemia due to dietary deficiency. Lancet I: 1004

    Google Scholar 

  • Fox JE, Bourdages R, Beck IT (1977) Effect of ethanol on glucose and water absorption in hamster jejunum in vivo. Am J Dig Dis 23: 193

    Google Scholar 

  • Fox JE, McElligott TF, Beck IT (1978a) Effect of ethanol on the morphology of hamster jejunum. Am J Dig Dis 23: 201

    PubMed  CAS  Google Scholar 

  • Fox JE, McElligott TF, Beck IT (1978b) The correlation of ethanol-induced depression of glucose and water transport with morphological changes in the hamster jejunum in vivo. Can J Physiol Pharmacol 56: 123

    PubMed  CAS  Google Scholar 

  • Franco D, Deporte A, Durandy Y, Bismuth H (1977) Upper gastrointestinal haemorrhage in hepatic cirrhosis: causes and relation to hepatic failure and stress. Lancet I: 218

    Google Scholar 

  • Franzen G (1928) Untersuchungen über Alkohol. VII. Mitt.-Alkoholwirkung auf die Magenverdauung. Arch Exp Pathol Pharmacol 134: 129

    Google Scholar 

  • Friedman AI, McEwan G (1963) Small bowel absorption in portal cirrhosis with ascites. Am J Gastroenterol 39:114

    PubMed  CAS  Google Scholar 

  • Friedman GD, Siegelaub AS, Seltzer C (1974) Cigarettes, alcohol, coffee and peptic ulcer. N Engl J Med 290: 469

    PubMed  CAS  Google Scholar 

  • Fromm D, Robertson R (1976) Effects of alcohol on ion trasnport by isolated gastric and esophageal mucosa. Gastroenterology 70: 220

    PubMed  CAS  Google Scholar 

  • Geall MG, Phillips SF, Summerskill WHJ (1970) Profile of gastric potential difference in man. Effects of aspirin, alcohol, bile, and endogenous acid. Gastroenterology 58: 437

    PubMed  CAS  Google Scholar 

  • Ghirardi P, Marzo A, Sardini D, Marchetti G (1971) Changes in intestinal absorption of glucose in rats treated with ethanol. Experientia 27: 61

    PubMed  CAS  Google Scholar 

  • Gibel W, Lohs Kh, Schremmer K, Wildner GP (1970) Experimentelle Untersuchungen über toxische Wirkungen von Alkoholbeistoffen. Dtsch Gesundheitsw 25: 573

    PubMed  CAS  Google Scholar 

  • Gibel W, Lohs KH, Wildner GP, Schramm T (1974) Experimentelle Untersuchungen zur kanzerogenen Wirkung höherer Alkohole am Beispiel von 3-Methyl-l-butanol, 1-Propanol und 2-Methyl-l-propanol. Z Exp Chir 7: 235

    PubMed  CAS  Google Scholar 

  • Göbel D (1977) Die chronisch-atrophische Gastritis aus klinischer Sicht. Med Klin 72: 1246

    PubMed  Google Scholar 

  • Goebell H, Bode Ch, Bastian H, Strohmeyer G (1970) Klinisch asymptomatische Funktionsstörungen des exokrinen Pankreas bei chronischen Alkoholikern. Dtsch Med Wochenschr 95: 808

    PubMed  CAS  Google Scholar 

  • Goetsch CA, Klipstein FA (1977) Effect of folate deficiency of the intestinal mucosa on jejunal transport in the rat. J Lab Clin Med 89: 1002

    PubMed  CAS  Google Scholar 

  • Goldberg ND, Haddox MK, Nicol SE (1975) Biologic regulation through apposing influences of cyclic GMP and cyclic AMP; the yin yang hypothesis. Adv Cyclic Nucleotide Res 5: 307

    PubMed  CAS  Google Scholar 

  • Gordon MJ, Skillman JJ, Edwards BG, Silen W (1974) Effects of ethanol, acetylsalicylic acid, acetaminophen, and ferrous sulfate on gastric mucosal permeability in man. Surgery 76: 405

    PubMed  CAS  Google Scholar 

  • Gottfried EB, Korsten MA, Lieber CS (1976) Gastritis and duodenitis induced by alcohol. Gastroenterology 70: 890

    Google Scholar 

  • Goulston EB, Cooke AR (1968) Alcohol, aspirin and gastrointestinal bleeding. Br Med J 4 J 4: 664

    CAS  Google Scholar 

  • Granerus G, Svensson SE, Wetterquist H (1969) Histamine in alcoholic drinks. Lancet I: 1320

    Google Scholar 

  • Grant R (1945) Rate of replacement of the surface epithelial cells of the gastric mucosa. Anat Rec 91: 175

    Google Scholar 

  • Gray JS, Bachrach WH (1940) Effect of atropin and fat on gastric secretion stimulated by alcohol. Proc Soc Exp Biol Med 43: 36

    CAS  Google Scholar 

  • Greene HL, Herman RH, Kraemer S (1971) Stimulation of jejunal adenyl cyclase by ethanol. J Lab Clin Med 78: 336

    PubMed  CAS  Google Scholar 

  • Greene HL, Stifel FB, Herman RH, Herman YF, Rosensweig NS (1974) Ethanol-induced inhibition of human intestinal enzyme activities: reversal by folic acid. Gastroenterology 67: 434

    PubMed  CAS  Google Scholar 

  • Griffaton GF, Faudemay C, Sautier C, Lowy R (1969) Absorption of glucose and lactic acid by everted intestinal loops in the rat after intraperitoneal injection of alcohol. Nutr Metab 11: 116

    Google Scholar 

  • Grisham CM, Barnett RE (1973) The effects of long-chain alcohols on membrane lipids and the (Na+ + K+)-ATPase. Biochim Biophys Acta 311: 417

    PubMed  CAS  Google Scholar 

  • Haggard HW, Greenberg LA (1940) Studies on the absorption, distribution and elimination of ethyl alcohol. V. The influence of glycocoll on absorption of alcohol. J Lab Clin Med 69: 116

    Google Scholar 

  • Halsted CH, Griggs RC, Harris JW (1967) The effect of alcoholism on the absorption of folic acid (H3PGA) evaluated by plasma levels and urine excretion. J Lab Clin Med 69: 116

    PubMed  CAS  Google Scholar 

  • Halsted CH, Robles EA, Mezey E (1971) Decreased jejunal uptake of labeled folic acid (3H-PGA) in alcoholic patients: roles of alcohol and nutrition. N Engl J Med 285: 701

    PubMed  CAS  Google Scholar 

  • Halsted CH, Robles EA, Mezey E (1973) Distribution of ethanol in the human intestinal tract. Am J Clin Nutr 26: 831

    PubMed  CAS  Google Scholar 

  • Hamilton SR, Yardley JH (1977) Regeneration of cardiac type mucosa and acquisition of Barrett mucosa after esophagogastrostomy. Gastroenterology 72: 669

    PubMed  CAS  Google Scholar 

  • Harichaux P, Moline J (1964) Influence d’une ingestion d’éthanol a 10 p. 100 sur l’evacuation gastrique chez la rat. CR Soc Biol (Paris) 158: 1389

    CAS  Google Scholar 

  • Harnett WL (1952) A survey of cancer in London. Report of the Clinical Cancer Research Committee. Br Emp Cancer Camp, London, p 834

    Google Scholar 

  • Hartmann L, Cornet A, Barbier J-Ph, Ollier M-P, Carnot Fr, Benisty H (1974) Réactions immunocytaires de la muqueuse gastrique au cours des cirrhoses alcooliques. Sem Hêp Paris 50: 1559

    CAS  Google Scholar 

  • Heitmann P (1974) Lower esophagus lined with columnar epithelium. In: Vantrappen G, Hellemans J (eds) Diseases of the esophagus. Springer, Berlin Heidelberg New York, p 525

    Google Scholar 

  • Hell D, Six P (1977) Thiamin-, Riboflavin-und Pyridoxin-Versorgung bei chronischem Alkoholismus. Dtsch Med Wochenschr 102: 962

    PubMed  CAS  Google Scholar 

  • Hellers G, Ewerth S, Ihre T, Lahnborg G (1978) The Mallory-Weiss syndrome. A review of 23 cases with special references to coagulation defects. Acta Chir Scand Suppl 482: 9

    PubMed  CAS  Google Scholar 

  • Hepner GW, Roginsky M, Moo HF (1976) Abnromal vitamin D metabolism in patients with cirrhosis. Am J Dig Dis 21: 527

    PubMed  CAS  Google Scholar 

  • Herbert V, Zalusky R, Davidson CS (1963) Correlation of folate deficiency with alcoholism and associated macrocytosis, anemia, and liver disease. Ann Intern Med 58: 977

    PubMed  CAS  Google Scholar 

  • Herbich J, Prokop L (1963) Untersuchungen über den Einfluß von Nahrungs-und Flüssigkeitsaufnahme auf den Blutalkoholspiegel. Wiener Klin Wochenschr 14: 421

    Google Scholar 

  • Herbst JJ, Berenson MM, McCloskey DW, Wiser WC (1978) Cell proliferation in esophageal columnar epithelium (Barrett’s esophagus). Gastroenterology 75: 683

    PubMed  CAS  Google Scholar 

  • Hermos JA, Adams WH, Liv YK, Sullivan LW, Trier JS (1972) Mucosa of the small intestine in folate-deficient alcoholics. Ann Intern Med 76: 957

    PubMed  CAS  Google Scholar 

  • Hétu C (1977) Activation métabolique des hépatotoxines et des cancerigenes: induction par l’alcool et les drogues. Union Med Can 106: 631

    PubMed  Google Scholar 

  • Hill CH (1960) The effect of alcohols on absorption and tissue uptake of trace elements. Fed Proc 28: 300

    Google Scholar 

  • Himal HS, Greenberg L (1977) The effect of ethanol and bile on electrolyte movement across canine proximal duodenal mucosa. Am J Gastroenterol 68: 45

    PubMed  CAS  Google Scholar 

  • Hirayama T (1955) Epidemiology of cancer of oesophagus. Jpn J Pub he Health 2: 658

    Google Scholar 

  • Hirschowitz BJ, Pollard HM, Hartwell SW, London J (1956) The action of ethyl alcohol on gastric acid secretion. Gastroenterology 30: 244

    PubMed  CAS  Google Scholar 

  • Hogan WJ, Viegas de Andrade SR, Winship DH (1972) Ethanol-induced acute esophageal motor dysfunction. J Appl Physiol 32: 755

    PubMed  CAS  Google Scholar 

  • Hoszowska-Owczarek A, Samochowiec L, Wojcicki J (1967) Experimental investigations in vitro on the effect of chronic alcohol administration on iron absorption in the small intestine of rats. Acta Physiol Pol 18: 349

    PubMed  CAS  Google Scholar 

  • Hoyumpa AM, Middleton HM, Wilson FA, Schenker S (1975a) Thiamine transport across the rat intestine. I. Normal characteristics. Gastroenterology 68: 1218

    PubMed  CAS  Google Scholar 

  • Hoyumpa AM, Breen KJ, Schenker S, Wilson FA (1975b) Thiamine transport across the rat intestine. II. Effect of ethanol. J Lab Clin Med 86: 803

    PubMed  CAS  Google Scholar 

  • Hoyumpa AM, Nichols SG, Wilson FA, Schenker S (1977) Effect of ethanol on intestinal (Na+, K+)ATPase and intestinal thiamine transport in rats. J Lab Clin Med 9); 1086

    Google Scholar 

  • Hoyumpa AM, Nichols S, Henderson GI, Schenker S (1978) Intestinal thiamin transport: effect of chronic ethanol administration in rats. Am J Clin Nutr 31: 938

    PubMed  CAS  Google Scholar 

  • Hunter JB, Moeller DD, Dunn GD, Klotz AP (1972) Alcoholic liver disease. The role of the small intestine. J Kans Med Soc 73: 425

    PubMed  CAS  Google Scholar 

  • Hyvärinen J, Sippel H, Linnankoski I, Roine R, Virtanen M, Olkinuora J, Nieminen U (1976) Absorption and elimination of alcohol in the monkey. Blutalkohol 13: 319

    Google Scholar 

  • Ingram LO (1976) Adaptation of membrane lipids to alcohols. J Bacteriol 125: 670

    PubMed  CAS  Google Scholar 

  • Inoue F, Frank GB (1967) Effects of ethyl alcohol on excitability and on neuromuscular transmission in frog skeletal muscle. Br J Pharmacol 30: 186

    CAS  Google Scholar 

  • Irsigler K, Pointner H, Kryspin-Exner K (1969) Xyloseresorption in Beziehung zu Leberfunktion und Ernährung bei chronischem Alkoholismus. Dtsch Med Wochenschr 94: 1532

    PubMed  CAS  Google Scholar 

  • Irvine WT, Watkin DB, Williams EJ (1960) The mechanism by which alcohol stimulates acid secretion. Gastroenterology 39: 41

    PubMed  CAS  Google Scholar 

  • Irvine WT, Ritchie HD, Adam HM (1961) Histamine concentrations in the gastric venous effluent before and during acid secretion. Gastroenterology 41: 258

    PubMed  CAS  Google Scholar 

  • Israel Y, Salazar J, Rosenmann E (1968) Inhibitory effects of alcohol on intestinal amino acid transport in vivo and in vitro. J Nutr 96: 499

    PubMed  CAS  Google Scholar 

  • Israel Y, Valenzela JE, Salazar J, Ugarte G (1969) Alcohol and amino acid transport in the human small intestine. J Nutr 98: 222

    PubMed  CAS  Google Scholar 

  • Jacobson ED, Thompson WJ (1976) Cyclic AMP and gastric secretion: the illusive second messenger. Adv Cyclic Nucleotide Res 7: 199

    PubMed  CAS  Google Scholar 

  • Johnston WD, Ballantyne AJ (1977) Prognostic effect of tobacco and alcohol use in patients with oral tongue cancer. Am J Surg 134: 444

    PubMed  CAS  Google Scholar 

  • Jorfeldt L, Juhlin-Dannfeldt A (1976) The influence of ethanol on splanchnic and skeletal muscle metabolism in man. Metabolism 27: 97

    Google Scholar 

  • Jung RT, Davie M, Hunter JO, Chalmers TM, Lawson DEM (1978) Abnormal vitamin D metabolism in cirrhosis. Gut 19: 290

    PubMed  CAS  Google Scholar 

  • Kalant H (1971) Absorption, distribution, and elimination of ethanol: effects on biological membranes. In: Kissin B, Begleiter H (eds) The biology of alcoholism. Plenum Press, New York London (Biochemistry, vol I, p 1)

    Google Scholar 

  • Karel L, Fleisher JH (1948) Gastric absorption of ethyl alcohol in the rat. Am J Physiol 153: 268

    PubMed  CAS  Google Scholar 

  • Karppanen H, Puurunen J (1976) Ethanol, indomethacin and gastric acid secretion in the rat. Eur J Pharmacol 35: 221

    PubMed  CAS  Google Scholar 

  • Karppanen H, Puurunen J, Kairaluoma M, Larmi T (1976) Effects of ethyl alcohol on the adenosine 3’,5’-monophosphate system of the human gastric mucosa. Scand J Gastroenterol 11: 603

    PubMed  CAS  Google Scholar 

  • Kaufman SE, Kaye MD (1978) Induction of gastro-oesophageal reflux by alcohol. Gut 193: 36

    Google Scholar 

  • Kay EB, Cross FS (1956) Chronic esophagitis. A possible factor in the production of carcinoma of the esophagus. Arch Intern Med 98: 475

    Google Scholar 

  • Keller AZ, Terris M (1965) The association of alcohol and tobacco with cancer of the mouth and pharynx. Am J Public Health 55: 1578

    CAS  Google Scholar 

  • Keller AZ (1967) Cirrhosis of the liver, alcoholism and heavy smoking associated with cancer of the mouth and pharynx. Cancer 20: 1015

    PubMed  CAS  Google Scholar 

  • Kerlin P, Barrett D, Kerr Grant A, Paull A (1978) The Mallory-Weiss lesion. A five-year experience. Med J Aust 65: 471

    Google Scholar 

  • Khodadoost J, Glass GBJ (1972) Erosive gastritis and acute gastroduodenal ulcerations as source of upper gastrointestinal bleeding in liver cirrhosis. Digestion 7: 129

    PubMed  CAS  Google Scholar 

  • Kilkowska K, Kryszewski A, Tyrakowska J (1976) Influence of ethyl alcohol on arylsulfatase and glycosidases in the epithelium of the small intestine in mice. Folia Morphol (Warsz) 35: 219

    CAS  Google Scholar 

  • Kiviranta UK (1952) Corrosion carcinoma of the esophagus. 381 cases of corrosion carcinoma. Acta Otolaryngol (Stockh) 42: 89

    PubMed  CAS  Google Scholar 

  • Kjellén G, Tibbling L (1978) Influence of body position, dry and water swallows, smoking, and alcohol on esophageal acid clearing. Scand J Gastroenterol 13: 283

    PubMed  Google Scholar 

  • Klipstein FA, Lindenbaum J (1965) Folate deficiency in chronic liver disease. Blood 25: 443

    PubMed  CAS  Google Scholar 

  • Korman MG, Soveny C, Hansky J (1971) Effect of food on serum gastrin evaluated by radioimmunoassay. Gut 12: 619

    PubMed  CAS  Google Scholar 

  • Krasner N, Cochran KM, Russel RI, Carmichael HA, Thompson GG (1976a) Alcohol and absorption from the small intestine. 1. Impairment of absorption from the small intestine in alcoholics. Gut 17: 245

    PubMed  CAS  Google Scholar 

  • Krasner N, Carmichael HA, Russell RJ, Thompson GG, Cochran KM (1976b) Alcohol and absorption from the small intestine. 2. Effect of ethanol on ATP and ATPase activities in guinea-pig jejunum. Gut 17: 249

    PubMed  CAS  Google Scholar 

  • Krawitt EL (1973) Ethanol inhibitis intestinal calcium transport in rats. Nature 243: 88

    PubMed  CAS  Google Scholar 

  • Krawitt EL (1974a) Effect of ethanol ingestion on duodenal calcium transport. J Lab Clin Med 85: 665

    Google Scholar 

  • Krawitt EL (1976b) Effect of acute ethanol administration on duodenal calcium transport. Proc Soc Exp Biol Med 146: 406

    Google Scholar 

  • Krebs HA, Perkins JR (1970) The physiological role of liver alcohol dehydrogenase. Biochem J 118: 635

    PubMed  CAS  Google Scholar 

  • Krueger L, MacIntosh FC (1937) Alcohol as a stomachic. Am J Dig Dis 4: 104

    CAS  Google Scholar 

  • Kuo YJ, Shanbour LL (1978) Effects of ethanol on sodium, 3-0-methyl glucose, and L-alanine transport in the jejunum. Am J Dig Dis 23: 51

    PubMed  CAS  Google Scholar 

  • Kuo YJ, Shanbour LL, Sernka TJ (1974) Effect of ethanol on permeability and ion transport in the isolated dog stomach. Am J Dig Dis 19: 818

    PubMed  CAS  Google Scholar 

  • Kürzinger R (1970) Bemerkungen über die Alkoholdiminution magenresezierter Personen. Dtsch Gesundheitsw 25: 2022

    PubMed  Google Scholar 

  • Kwan KW (1937) Carcinoma of the esophagus. A statistical study. Chin Med J (Engl) 52: 237

    Google Scholar 

  • Langman MJS (1973) Changing patterns in the epidemiology of peptic ulcer. Clin Gastroenterol 2: 219

    Google Scholar 

  • Larato DC (1973) Gewebeveränderungen in der Mundhöhle bei chronischen Alkoholikern. Quintessenz 12: 131

    Google Scholar 

  • Layne JA, Carey JB (1943) An endoscopic study of appearance of the anesthetized dog. Gastroenterology 1: 690

    CAS  Google Scholar 

  • Leake CD, Silverman M (1971) The chemistry of alcoholic beverages. In: Kissin B, Begleiter H (eds) The biology of alcoholism, vol 1. Plenum Press, New York London, p 575

    Google Scholar 

  • Le Breton E (1936) Influence de jeune sur la vitesse d’oxydation de l’alcool éthylique chez le rat blanc. CR Soc Biol (Paris ) 122: 330

    Google Scholar 

  • Lee FJ (1966) Cirrhosis and hepatoma in alcoholics. Gut 7: 77

    PubMed  CAS  Google Scholar 

  • Leevy CM, Baker HM (1968) Vitamins and alcoholism. Am J Clin Nutr 21: 1325

    PubMed  CAS  Google Scholar 

  • Leevy CM, Gellene R, Ning M (1964) Primary liver cancer in cirrhosis of the alcoholic. Ann NY Acad Sci 114: 1026

    Google Scholar 

  • Leevy CM, Baker H, Tenhove W, Frank O, Cherrick GR (1965) B-complex vitamins in liver disease of the alcoholic. Am J Clin Nutr 16: 339

    PubMed  CAS  Google Scholar 

  • Lereboullet J (1970) Les variations du taux d’alcoolémie en fonction de la nature des boissons ingérées. Bull Acad Nat Med (Paris) 154: 427

    CAS  Google Scholar 

  • Lieber CS (1973) Hepatic and metabolic effects of alcohol (1966–1973). Gastroenterology 65: 821

    PubMed  CAS  Google Scholar 

  • Lieber CS, DeCarli LM (1970) Hepatic microsomal ethanol-oxidizing system. J Biol Chem 245: 2505

    PubMed  CAS  Google Scholar 

  • Lillibridge CB, Yoshimori M, Chey WY (1973) Observations on the ultrastructure of oxyntic cells in alcohol-fed dogs. Am J Dig Dis 18: 443

    PubMed  CAS  Google Scholar 

  • Lim P, Jacob E (1972) Magnesium status of alcoholic patients. Metabolism 21: 1045

    PubMed  CAS  Google Scholar 

  • Lindenbaum J (1977) Cytotoxic effects of alcohol on hematopoietic and intestinal cells. Adv Exp Med Biol 85 A: 415

    Google Scholar 

  • Lindenbaum J, Lieber CS (1969) Alcohol-induced malabsorption of vitamin B12 in man. Nature 224: 806

    PubMed  CAS  Google Scholar 

  • Lindenbaum J, Lieber CS (1975) Effects of chronic ethanol administration on intestinal absorption in man in the absence of nutritional deficiency. Ann NY Acad Sci 252: 229

    Google Scholar 

  • Linscheer WG, Patterson JF, Moore EW, Clermont RJ, Robins SJ, Chalmers TC (1966) Medium and long chain fat absorption in patients with cirrhosis. J Clin Invest 45: 1317

    PubMed  CAS  Google Scholar 

  • Loh TT, Juggi JS (1978) Changes in the blood and iron metabolism in rats with alcoholic fatty livers. Proc Soc Exp Biol Med 150: 537

    Google Scholar 

  • Long RG, Skinner RK, Wills MR, Sherlock S (1976) Serum-25-hydroxyvitamin-D in untreated parenchymal and cholestatic liver disease. Lancet II: 650

    Google Scholar 

  • Lorenz W, Troidl H, Barth H, Rohde H, Schulz S, Becker H, Dormann P, Schmal A, Kusche J, Meyer R (1976) Stimulus-secretion coupling in the human and canine stomach: role of histamine. In: Case RM, Goebell H (eds) Stimulus-secretion coupling in the gastrointestinal tract. MTP Press, Lancaster, p 177

    Google Scholar 

  • Losowsky MS, Leonard PJ (1967) Evidence of vitamin E deficiency in patients with malabsorption or alcoholism and the effects of therapy. Gut 8: 539

    PubMed  CAS  Google Scholar 

  • Losowsky MS, Walker BE (1969) Liver disease and malabsorption. Gastroenterology 56: 589

    PubMed  CAS  Google Scholar 

  • Luisier M, Vodoz JF, Donath A, Courvoisier B, Garcia B (1977) Carence en 25-hydroxyvitamine D avec diminution de l’absorption intestinale de calcium et de la densité osseuse dans l’alcoolisme chronique. Schweiz Med Wochenschr 107: 1529

    PubMed  CAS  Google Scholar 

  • Lund B, Sorensen OH, Hilden M, Lund B (1977) The hepatic conversion of vitamin D in alcoholics with varying degrees of liver affection. Acta Med Scand 202: 221

    PubMed  CAS  Google Scholar 

  • Lundquist F, Tygstrup N, Winkler K, Mellemgaard K, Munck-Petersen S (1962) Ethanol metabolism and production of free acetate in the human liver. J Clin Invest 41: 955

    PubMed  CAS  Google Scholar 

  • Madzarovova-Nohejlova J (1971) Intestinal disaccharidase activity in adults and chronic pilsen beer drinkers. Biol Gastroenterol (Paris) 4: 325

    CAS  Google Scholar 

  • Main JHM, Whittle BJR (1976) The role of prostaglandins in gastric acid secretion. In: Case RM, Goebell H (eds) Stimulus-secretion coupling in the gastrointestinal tract. MTP Press, Lancaster, p 147

    Google Scholar 

  • Mammoser LF, Albi RW, Boyd TE (1929) Studies on absorption of histamine from the intestine. Am J Physiol 50: 444

    Google Scholar 

  • Marin GA, Clark ML, Senior JR (1969) Studies of malabsorption occurring in patients with Laennec’s cirrhosis. Gastroenterology 56: 727

    Google Scholar 

  • Marquardt P, Werringloer J (1965) Untersuchungen zur Ursache akuter und chronischer Schäden durch Weingenuß. Wein-Wissenschaft 20: 260

    Google Scholar 

  • Martin S, Pangborn RM (1971) Human parotid secretion in response to ethyl alcohol. J Dent Res 50: 485

    PubMed  CAS  Google Scholar 

  • Martini GA, Wienbeck M (1974) Begünstigt Alkohol die Entstehung eines Barrett-Syndroms (Endobrachyosöphagus)? Dtsch Med Wochenschr 99: 434

    PubMed  CAS  Google Scholar 

  • Mawdsley C, Mayer RF (1965) Nerve conduction in alcoholic polyneuropathy. Brain 88: 335

    PubMed  CAS  Google Scholar 

  • Mayer EM, Grabowski CJ, Fischer RS (1978) Effects of graded doses of alcohol upon esophageal motor function. Gastroenterology 75: 1133

    PubMed  CAS  Google Scholar 

  • McDonald GB, Brand DL, Thorning DR (1977) Multiple adenomatous neoplasms arising in columnar-lined (Barrett’s) esophagus. Gastroenterology 72: 1317

    PubMed  CAS  Google Scholar 

  • McGlashan ND (1968) Esophageal cancer and contaminated alcoholic spirits. An exercise in medical geography. Int Pathol 9: 50

    Google Scholar 

  • McGlashan ND, Walters CL, McLean AE (1968) Nitrosamines in African alcoholic spirits and oesophageal cancer. Lancer II: 1017

    Google Scholar 

  • McGlashan ND, Patterson RLS, Williams AA (1970) N-Nitrosamines and grain-based spirits. Lancet II: 1138

    Google Scholar 

  • Mekhjian HS, May ES (1977) Acute and chronic effects of ethanol on fluid transport in the human small intestine. Gastroenterology 72: 1280

    PubMed  CAS  Google Scholar 

  • Messian R, Hermos JA, Robbins AH, Friedlander DM, Schimmel EM (1978) Barrett’s esophagus. Am J Gastroenterol 69: 458

    PubMed  CAS  Google Scholar 

  • Meunier P, Dechavanne M, Prost G (1978) L’os des cirrhotiques etudie par lecture quantitative de la biopsie osseuse. Lyon Med 229: 1089

    Google Scholar 

  • Mezey E (1975) Intestinal function in chronic alcoholism. Ann NY Acad Sci 252: 215

    PubMed  CAS  Google Scholar 

  • Mezey E, Jow E, Slavin RE, Tobon F (1970) Pancreatic function and intestinal absorption in alcoholism. Gastroenterology 59: 657

    PubMed  CAS  Google Scholar 

  • Middleton WRJ, Carter EA, Drummey GD, Isselbacher KJ (1971) Effect of oral ethanol administration on intestinal cholesterogenesis in the rat. Gastroenterology 60: 880

    PubMed  CAS  Google Scholar 

  • Mistilis SP, Garske A (1969) Induction of alcohol dehydrogenase in liver and gastrointestinal tract. Aust Ann Med 18: 227

    PubMed  CAS  Google Scholar 

  • Mistilis S, Ockner RK (1972) Effects of ethanol on endogenous lipid and lipoprotein metabolism in small intestine. J Lab Clin Med 80: 34

    PubMed  CAS  Google Scholar 

  • Mitchell CJ, Jewell DP (1977) The diagnosis of the site of upper gastrointestinal haemorrhage in patients with established portal hypertension. Endoscopy 9: 131

    PubMed  CAS  Google Scholar 

  • Mitjavila S, Lacombe C, Carrera G (1976) Changes in activity of rat brush border enzymes incubated with a homologous series of aliphatic alcohols. Biochem Pharmacol 25: 625

    PubMed  CAS  Google Scholar 

  • Mosbech J, Videbaek A (1955) On the etiology of esophageal carcinoma. J Natl Cancer Inst 15: 1665

    PubMed  CAS  Google Scholar 

  • Moser K, Papenberg J, von Wartburg JP (1968) Heterogenität und Organverteilung der Alkoholdehydrogenase bei verschiedenen Spezies. Enzyme 9: 447

    CAS  Google Scholar 

  • Murray J, Stein N (1965) Effect of ethanol on absorption of iron in rats. Proc Soc Exp Biol Med 120: 816

    PubMed  CAS  Google Scholar 

  • Murray RF, Motulsky AG (1971) Developmental variation in the isoenzymes of human liver and gastric alcohol dehydrogenase. Science 171: 71

    PubMed  CAS  Google Scholar 

  • Naef AP, Savary M, Ozzello L (1975) Columnar-lined lower esophagus: an acquired lesion with malignant predisposition. J Thorac Cardiovasc Surg 70: 826

    PubMed  CAS  Google Scholar 

  • Newman HW, Mehrtens HG (1932) Effects of intravenous injection of ethyl alcohol on gastric acid secretion in man. Proc Soc Exp Biol Med 30: 145

    CAS  Google Scholar 

  • Nilsson BE, Westlin NE (1972) Femur density in alcoholism and after gastrectomy. Calcif Tissue Res 10: 167

    PubMed  CAS  Google Scholar 

  • Nilsson BE, Westlin NE (1973) Changes in bone mass in alcoholics. Clin Orthop 90: 229

    PubMed  Google Scholar 

  • Nordin BEC (1976) Calcium, phosphate and magnesium metabolism. Churchill & Livingstone, Edinburgh

    Google Scholar 

  • Novak DJ, Victor M (1974) The vagus and sympathic nerves in alcoholic polyneuropathy. Arch Neurol 30: 273

    PubMed  CAS  Google Scholar 

  • O’Keane M, Smith S, Goldberg A (1971) Gastric erosions caused by homebrewed lager. Lancet II: 795

    Google Scholar 

  • Ostrow JD, Timmerman RJ, Gray SJ (1971) Gastric erosions in human hepatic cirrhosis. Gastroenterology 38: 303

    Google Scholar 

  • Payne JP, Hill DW, King NW (1966) Observations on the distribution of alcohol in blood, breath and urine. Br Med J 1: 196

    PubMed  CAS  Google Scholar 

  • Pell S, D’Alonzo CA (1973) A five-year mortality study of alcoholics. J Occup Med 15: 120

    PubMed  CAS  Google Scholar 

  • Perlow W, Baraona E, Lieber CS (1977) Symptomatic intestinal disaccharidase deficiency in alcoholics. Gastroenterology 72: 680

    PubMed  CAS  Google Scholar 

  • Pfaffenbarger RS, Wing AL, Hyde RT (1974) Chronic disease in former college students. XIII. Early precursors of peptic ulcer. Am J Epidemiol 100: 307

    Google Scholar 

  • Pikanen TA (1957) Neurological and physiological studies on distilled and brewed beverages. Ann Med Exp Biol Fenn 35: (Suppl) 9

    Google Scholar 

  • Piquet J, Tison (1937) Alcool et cancer de l’oesophage. Bull Acad Med (Toronto) 117: 236

    Google Scholar 

  • Pirola RC, Davis AE (1968) Effects of ethyl alcohol on sphincteric resistance at the choledocho-duodenal junction in man. Gut 9: 557

    PubMed  CAS  Google Scholar 

  • Pirola RC, Davis AE (1970) Effects of intravenous alcohol on motility of the duodenum and of the sphincter of oddi. Aust Ann Med 1: 24

    Google Scholar 

  • Pirola RC, Bolin TD, Davis AE (1969) Does alcohol cause duodenitis? Am J Dig Dis 14: 239

    PubMed  CAS  Google Scholar 

  • Pitchumoni CS, Lopes JD, Glass GBJ (1975) The prevalence of gastric autoantibodies in chronic alcoholics. Am J Gastroenterol 64: 187

    PubMed  CAS  Google Scholar 

  • Planche NE, Chau-Huu T, Lai PP, Sarles H (1977) Chronic alcohol consumption does not modify cholecystokinin blood levels estimated by bioassay in the dog. Digestion 16: 194

    PubMed  CAS  Google Scholar 

  • Pope CE (1976) Is LES enough? Gastroenterology 71: 328

    PubMed  CAS  Google Scholar 

  • Pothe H, Voigtsberger P (1976) Zur Epidemiologie und Diagnostik des Ösophaguskarzinoms. Dtsch Gesundheitsw 31: 2148

    Google Scholar 

  • Powell LW (1975) The role of alcoholism in hepatic iron storage disease. Ann NY Acad Sci 252: 124

    PubMed  CAS  Google Scholar 

  • Pratt RF, Cooper BA (1971) Folates in plasma and bile of man after feeding folic acid-3H and 5-formyltetrahydrofolate (folinic acid). J Clin Invest 50: 455

    PubMed  CAS  Google Scholar 

  • Puurunen J (1978) Studies on the mechanism of the inhibitory effect of ethanol on the gastric acid output in the rat. Naunyn-Schmiedeberg’s Arch Pharmacol 303: 87

    CAS  Google Scholar 

  • Puurunen J, Karppanen H (1975) Effects of ethanol on gastric acid secretion and gastric mucosal cyclic AMP in the rat. Life Sci 16: 1513

    PubMed  CAS  Google Scholar 

  • Puurunen J, Karppanen H, Kairaluoma M, Larmi T (1976) Effects of ethanol on the cyclic AMP system of the dog gastric mucosa. Eur J Pharmacol 38: 275

    PubMed  CAS  Google Scholar 

  • Puurunen J, Hiltunen K, Karppanen H (1977) Ethanol induced changes in gastric mucosal content of cyclic AMP and ATP in the rat. Eur J Pharmacol 42: 85

    PubMed  CAS  Google Scholar 

  • Racusen LC, Krawitt EL (1977) Effect of folate deficiency and ethanol ingestion on intestinal folate absorption. Am J Dig Dis 22: 915

    PubMed  CAS  Google Scholar 

  • Ramwell PW, Shaw JE (1968) Prostaglandin inhibition of gastric secretion. J Physiol 195: 34

    Google Scholar 

  • Rauschke J (1952) Über die Blutalkoholkurve im Stadium der Resorption. Dtsch Z Gerichtl Med 41: 474

    CAS  Google Scholar 

  • Remmer H (1971) Discussion remark. In: Gerok W, Sickinger K, Hennekeuser HH (eds) Alkohol und Leber. Schattauer, Stuttgart New York, p 326

    Google Scholar 

  • Roberts DM (1972) Chronic gastritis, alcohol and non-ulcer dyspepsia. Gut 13: 768

    PubMed  CAS  Google Scholar 

  • Roberts DM, Taylor G (1973) Gastric parietal cell antibodies in young men with alcoholism and with non-ulcer dyspepsia. Digestion 9: 30

    PubMed  CAS  Google Scholar 

  • Robles EA, Mezey E, Halsted CH, Schuster MM (1974) Effect of ethanol on motility of the small intestine. Hopkins Med J 135: 17

    CAS  Google Scholar 

  • Rodgers JB, O’Brien BA (1975) The effect of acute ethanol treatment on lipid-reesterifying enzymes in the rat small bowel. Am J Dig Dis 20: 345

    Google Scholar 

  • Roggin GM, Iber FL, Kater RMH, Tabon F (1969) Malabsorption in the chronic alcoholic. Hopkins Med J 125: 321

    CAS  Google Scholar 

  • Robbin GM, Iber FL, Linscheer WG (1972) Intraluminal fat digestion in the chronic alcoholic. Gut 13: 107

    Google Scholar 

  • Rossi MA, Zucoloto S (1977) Effect of chronic alcohol ingestion on the small intestinal ultrastructure in rats. Beitr Pathol 161: 50

    PubMed  CAS  Google Scholar 

  • Roth JLA (1974) Drug induced lesions. In: Bockus HL (ed) Gastroenterology, vol I, 3rd ed. Saunders, Philadelphia, p 487

    Google Scholar 

  • Rothman K, Keller AI (1972) The effect of joint exposure to alcohol and tobacco on risk of cancer of the mouth and pharynx. J Chronic Dis 25: 711

    PubMed  CAS  Google Scholar 

  • Rubin E, Beattie DS, Lieber CS (1970) Effects of ethanol on the biogenesis of mitochondiral membranes and associated mitochondrial functions. Lab Invest 23: 620

    PubMed  CAS  Google Scholar 

  • Rubin E, Rybak BJ, Lindenbaum J, Gerson CD, Walker G, Lieber CS (1972) Ultrastructural changes in the small intestine induced by ethanol. Gastroenterology 63: 801

    PubMed  CAS  Google Scholar 

  • Sadeghi A, Behmard S, Shafiepoor H, Zeighmani E (1977) Cancer of the esophagus in Southern Iran. Cancer 40: 841

    PubMed  CAS  Google Scholar 

  • Saint-Blanquat G de, Derache R (1966) Effet de l’ethanol sur la sécrétion acide de l’estomac in vitro chez le rat. Biochem Pharmacol 15: 1896

    Google Scholar 

  • Saint-Blanquat G de, Derache R (1967) Effet d’une intoxication aigue par l’éthanol sur le taux de l’histamine dans le tractus digestif chez le rat. Thérapie 22: 1045

    PubMed  Google Scholar 

  • Saint-Blanquat G de, Derache R (1971) Effets de l’administration de l’éthanol sur la teneur en gastrine de l’estomac de rat. J Physiol (Paris) 63: 539

    Google Scholar 

  • Saint-Blanquat G de, Derache R (1972) Action de l’éthanol sur la physiologie gastrique. Biol Gastroenterol (Paris) 5: 97

    Google Scholar 

  • Salvesen H, Kolberg A (1958) Alcohol absorption in idiopathic steatorrhea. Acta med Scand 161: 135

    PubMed  CAS  Google Scholar 

  • Sarles H (1974) Chronic calcifying pancreatitis — chronic alcoholic pancreatitis. Gastroenterology 66: 604

    PubMed  CAS  Google Scholar 

  • Sarles H, Tiscornia D, Talasciano G (1977) Chronic alcoholism and canine exocrine pancreas secretion: a long-term follow up study. Gastroenterology 72: 238

    PubMed  CAS  Google Scholar 

  • Schafer DF, Stephenson DV, Barak AJ, Sorrell MF (1974) Effects of ethanol on the transport of manganese by small intestine of the rat. J Nutr 104: 101

    PubMed  CAS  Google Scholar 

  • Schmidt W, Lint J de (1972) Causes of death of alcoholics. J Stud Alcohol 33: 171

    CAS  Google Scholar 

  • Schmidt W, Popham RE (1975/76) Heavy alcohol consumption and physical health problems: a review of the epidemiological evidence. Drug Alcohol Depend 1: 27

    PubMed  CAS  Google Scholar 

  • Schmidt-Wilcke HA, Martini GA (1975) Akute und chronische Alkoholschäden im Bereich des Gastrointestinaltraktes. Dtsch Med Wochenschr 100: 700

    PubMed  CAS  Google Scholar 

  • Schneider RP, Bernstein RB (1973) A comparison of gastric acid back diffusion in control and alcoholic patients. Am J Dig Dis 18: 567

    PubMed  CAS  Google Scholar 

  • Schuller PL, Ockhuizen Th, Werringloer J, Marquardt P (1967) Aflatoxin B1 und Histamin in Wein. Arzneim Forsch 17: 888

    CAS  Google Scholar 

  • Schulte RM (1978) Magnesiumstoffwechselstörungen bei Patienten mit chronischer nicht-alkoholbedingter Leberkrankheit und mit chronischem Alkoholismus. Dissertation FB Humanmedizin, Marburg

    Google Scholar 

  • Schultz SG (1977) Sodium-coupled solute transport by small intestine: a status report. Am J Physiol 233: 249

    Google Scholar 

  • Schwartz D, Lellouch J, Flamant R, Denoix PF (1962) Alcool et cancer. Résultats d’une enquête rétrospective. Rev Fr Etudes Clin Biol 7: 590

    CAS  Google Scholar 

  • Scobie BA, Summerskill WHJ (1964) Reduced gastric output in cirrhosis: quantitation and relationships. Gut 5: 422

    PubMed  CAS  Google Scholar 

  • Sernka ThJ, Jackson AF (1976) Responses to ethanol in rat stomach. Nutr Rep Intern 14: 415

    CAS  Google Scholar 

  • Sernka ThJ, Gilleland CW, Shanbour LL (1974) Effects of ethanol on active transport in the dog stomach. Am J Physiol 226: 396

    Google Scholar 

  • Shanbour LL, Miller J, Chowdhury TK (1973) Effects of alcohol on active transport in the rat stomach. Am J Dig Dis 18: 311

    PubMed  CAS  Google Scholar 

  • Silen W, Skillman JJ (1974) Stress ulcer, acute erosive gastritis and the gastric mucosal barrier. Adv Intern Med 19: 195

    PubMed  CAS  Google Scholar 

  • Sklan D, Tostler N (1977) Site and extent of thiamine absorption in the rat. J Nutr 107: 353

    PubMed  CAS  Google Scholar 

  • Small M, Longarini A, Zamcheck N (1959) Disturbances of digestive physiology following acute drinking episodes in “Skid-Row” alcoholics. Am J Med 27: 575

    PubMed  CAS  Google Scholar 

  • Smith ME (1973) The uptake of pteroyl-glutamic acid by the rat jejunum. Biochim Biophys Acta 298: 124

    PubMed  CAS  Google Scholar 

  • Smith ME, Newman HW (1959) The rate of ethanol metabolism in fed and fasting animals. J Biol Chem 234: 1544

    PubMed  CAS  Google Scholar 

  • Smith BM, Skillman JJ, Edwards BG, Silen W (1971) Permeability of the human gastric mucosa: Alteration by acetylsalicylic acid and ethanol. N Engl J Med 285: 716

    PubMed  CAS  Google Scholar 

  • Soeder M (1957) Trunksucht nach Magenresektion. Nervenarzt 28: 228

    PubMed  CAS  Google Scholar 

  • Sorg SK (1972) Ethanol produces muscle damage in human volunteers. Science 175: 327

    Google Scholar 

  • Spencer RP, Brody KR, Lutters BM (1964) Some effects of ethanol on the gastrointestinal tract. Am J Dig Dis 9: 599

    PubMed  CAS  Google Scholar 

  • Stefenelli N, Prießnitz E, Klotz H, Hahn S (1977) Die Beeinflußbarkeit der Alkoholresorption durch Änderung der Magenentleerung. Wiener Klin Wochenschr 89: 161

    CAS  Google Scholar 

  • Stein SW, Lieber CS, Leevy CM, Cherrick GR, Abelmann WH (1963) The effect of ethanol upon systemic and hepatic blood flow in the man. Am J Clin Nutr 13: 68

    PubMed  CAS  Google Scholar 

  • Steiner P (1956) The etiology and histogenesis of carcinoma of the esophagus. Cancer 9: 436

    PubMed  CAS  Google Scholar 

  • Straus B, Berenyi MR, Huang J-M, Straus E (1971) Delayed hypersensitivity in alcoholic cirrhosis. Dig Dis 16: 509

    CAS  Google Scholar 

  • Straus E, Urbach HJ, Yalow RS (1975) Alcohol-stimulated secretion of immunoreactive secretin. N Engl J Med 293: 1031

    PubMed  CAS  Google Scholar 

  • Strohmeyer G (1972) Eisen-und Kupferstoffwechsel. In: Bock HE, Hartmann F (eds) Klinik der Gegenwart, vol 10. Urban & Schwarzenberg, München, p 147

    Google Scholar 

  • Subramarian N, Mitznegg P, Domschke W (1978) A rapid and sensitive enzymatic-isotopic method for routine assay of histamine in blood, plasma and biopsy tissue: reevaluation. Acta Hepatogastroenterol (Stuttg) 25: 456

    Google Scholar 

  • Sullivan JF (1962) Effect of alcohol on urinary zinc excretion. J Stud Alcohol 23: 216

    CAS  Google Scholar 

  • Sun DCH, Albacete RA, Chen JK (1967) Malabsorption studies in cirrhosis of the liver. Arch Intern Med 119: 567

    PubMed  CAS  Google Scholar 

  • Sunano S, Myzaki E (1969) Effects of ethanol and acetone on action potential and inhibitory potential of guinea-pig taenia coli. Nature 221: 380

    PubMed  CAS  Google Scholar 

  • Sundby P (1967) Alcoholism and mortality. National Institute for Alcohol Research, Universitetsforlaget, Oslo

    Google Scholar 

  • Tague LL, Shanbour LL (1977) Effects of ethanol on bicarbonate-stimulated ATPase, ATP, and cyclic AMP in canine gastric mucosa. Proc Soc Exp Biol Med 154: 37

    PubMed  CAS  Google Scholar 

  • Tanaka M (1972) Effects of alcoholic drinks on the human stomach. Jpn J Gastroenterol 69: 36

    CAS  Google Scholar 

  • Tappert EJ, Bushi S, Ruppert RD, Greenberger NJ (1968) Effect of acute and chronic ethanol treatment on the absorption of iron in rats. Am J Med Sci 255: 46

    Google Scholar 

  • Thiel H (1978) Zur Problematik des “hepatogenen Ulkus”. Z Gastroenterol 16: 73

    PubMed  CAS  Google Scholar 

  • Thiel DH van, Lester R (1974) Sex, ascites and alcoholism in survival of patients with cirrhosis. N Engl J Med 291: 251

    PubMed  Google Scholar 

  • Thomson AD, Baker H, Leevy CM (1970) Patterns of 3 5S-thiamine hydrochloride absorption in the malnourished alcoholic patients. J Lab Clin Med 76: 34

    PubMed  CAS  Google Scholar 

  • Tiscornia O, Sarles H, Voirol M, Levesque D, Drieniszewski J, Palasciano G, Cavarzan A, Teixeira A, Bretholz A, Langier R, Singer M, Demol P, Oliveira JPM de (1976) Evidences for duodenopancreatic reflex and an anti-CCK factor with lidocaine infused intravenously and sprayed topically on pancreatic papilla in nonalcoholic and alcohol-fed dogs. Am J Gastroenterol 66: 221

    PubMed  CAS  Google Scholar 

  • Tomasulo PA, Kater RMH, Iber FL (1968) Impairment of thiamine absorption in alcoholism. Amer J Clin Nutr 21: 1341

    PubMed  CAS  Google Scholar 

  • Tuyns AJ (1970) Cancer of the esophagus: further evidence of the relation to drinking habits in France. Int J Cancer 5: 152

    PubMed  CAS  Google Scholar 

  • Ullrich W, Weber P, Wollenberg P (1975) Tetrahydrofurane — An inhibitor for ethanolinduced liver microsomal cytochrome p-450. Biochem Biophys Res Commun 64: 808

    PubMed  CAS  Google Scholar 

  • Underwood EJ (1971) Trace elements in animal nutrition. Academic Press, New York

    Google Scholar 

  • Verdy M, Caron D (1973) Ethanol et absorption du calcium chez l’humain. Biol Gastroenterol (Paris) 6: 157

    CAS  Google Scholar 

  • Vesely DL, Levey GS (1977) Ethanol-induced inhibition of guanylate cyclase in liver, pancreas, stomach, and intestine. Res Comm Chem Pathol Pharmacol 17: 215

    CAS  Google Scholar 

  • Vincent RG, Marchetta F (1963) The relationship of the use of tobacco and alcohol to cancer of the oral cavity, pharynx or larynx. Am J Surg 106: 501

    PubMed  CAS  Google Scholar 

  • Vitale JJ, Coffey J (1971) Alcohol and vitamin metabolism. In: Kissin B, Begleiter H (eds) The biology of alcoholism. Plenum Press, New York, p 327

    Google Scholar 

  • Vodoz JF, Luisier M, Donath A, Courvoisier B, Garcia B (1977) Diminution de 1’absorption intestinale de 47-calcium dans l’alcoolisme chronique. Schweiz Med Wochenschr 107: 1525

    PubMed  CAS  Google Scholar 

  • Walker WA, Isselbacher KJ (1974) Uptake and transport of macromolecules by the intestine. Possible role in clinical disorders. Gastroenterology 67: 531

    PubMed  CAS  Google Scholar 

  • Wartburg JP von (1971) The metabolism of alcohol in normals and alcoholics: enzymes. In: Kissin B, Begleiter H (eds) The biology of alcoholism, vol 1. Plenum Press, New York, p 63

    Google Scholar 

  • Weir JM, Dunn jr JE (1970) Smoking and mortality; a prospective study. Cancer 25: 105

    PubMed  CAS  Google Scholar 

  • Weise RE, Schapiro H, Woodward ER (1961) Effect of parenteral alcohol on gastric secretion. Surg Forum 12: 281

    PubMed  CAS  Google Scholar 

  • Widmark MP (ed) (1932) Die theoretischen Grundlagen und die praktische Verwendbarkeit der gerichthch-medizinischen Alkoholbestimmung. Urban & Schwarzenberg, Berlin

    Google Scholar 

  • Wilson FA, Hoyumpa AM (1979) Ethanol and small intestinal transport. Gastroenterology 76: 388

    PubMed  CAS  Google Scholar 

  • Wilson JD, Onstad GR, Williams RC, Carey JB (1968) Selective immunoglobulin A deficiency in two patients with alcoholic cirrhosis. Gastroenterology 54: 253

    PubMed  CAS  Google Scholar 

  • Winawer SJ, Sullivan LW, Herbert V, Zamcheck N (1965) The jejunal mucosa in patients with nutritional folate deficiency and megaloblastic anemia. N Engl J Med 272: 892

    PubMed  CAS  Google Scholar 

  • Winship DH, Caflisch CR, Zboralske FF, Hogan WJ (1968) Deterioration of esophageal peristalsis in patients with alcoholic neuropathy. Gastroenterology 55: 173

    PubMed  CAS  Google Scholar 

  • Winsor AL, Strongin EJ (1933) The effect of alcohol on the rate of parotid secretion. J Exp Psychol (Gen) 16: 589

    Google Scholar 

  • Wojcicki J, Samochowiec L, Kadykow M (1972) Effect of ethanol on iron absorption in the amsll intestine of rats. J Stud Alcohol 33: 958

    CAS  Google Scholar 

  • Wolff G (1970) Does alcohol cause chronic gastritis? Scand J Gastroenterol 5: 289

    PubMed  CAS  Google Scholar 

  • Woodward ER, Robertson C, Ruttenberg HD, Schapiro HD (1957) Alcohol as a gastric secretory stimulant. Gastroenterology 32: 727

    PubMed  CAS  Google Scholar 

  • Worthington BS, Boatman E (1976) Intestinal permeability to large particles in normal and protein deficient adult rats. J Nutr 106: 20

    PubMed  CAS  Google Scholar 

  • Worthington BS, Meserole L, Syrotuck JA (1978) Effect of daily ethanol ingestion on intestinal permeability to macromolecules. Dig Dis 23: 23

    CAS  Google Scholar 

  • Wu YK, Loucks HH (1951) Carcinoma of esophagus or cardia of stomach; analysis of 172 cases with 81 scSections. Ann Surg 134: 946

    PubMed  CAS  Google Scholar 

  • Würsch TG, Hess H, Walser R, Koelz HR, Pelloni S, Vogel E, Schmidt P, Blum AL (1978) Die Epidemiologic des Ulcus duodeni. Untersuchung an 1105 Patienten in Zürich. Dtsch Med Wochenschr 103: 613

    PubMed  Google Scholar 

  • Wynder EL, Bross IJ (1961) A study of etiological factors in cancer of esophagus. Cancer 14: 389

    PubMed  CAS  Google Scholar 

  • Wynder EL, Bross IJ, Feldman RM (1957) Study of etiological factors in cancer of the mouth. Cancer 10: 1300

    PubMed  CAS  Google Scholar 

  • Wynder EL, Reddy BS, McCoy GD, Weisburger JH, Williams GM (1976) Diet and gastrointestinal cancer. In: Sherlock S, Zamcheck N (eds) Cancer of the GI tract. Clin Gastroenterol 5: 463

    Google Scholar 

  • Williams AW (1956) Effect of alcohol on gastric mucosa. Br J Med 1: 256

    CAS  Google Scholar 

  • Yoshimori M, Chey NY, Escoffery R, Lillibridge C (1972) Effects of ethanol on gastric secretion of acid and parietal cells in dogs. Gastroenterology 62: 732

    Google Scholar 

  • Zeus J (1970) Histologische Untersuchungen am distalen Ösophagus zur Pathogenese der Ösophagitis unter besonderer Berücksichtigung der Beziehung zum Sodbrennen. Dissertation, Erlangen

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Med. Klinik der Univ. Marburg, Mannkopffstr. 1, D-3550, Marburg/Lahn, Germany

    J. Ch. Bode

Authors
  1. J. Ch. Bode
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

P. Frick G.-A. von Harnack G. A. Martini A. Prader

Rights and permissions

Reprints and permissions

Copyright information

© 1980 Springer-Verlag Berlin Heidelberg

About this paper

Cite this paper

Bode, J.C. (1980). Alcohol and the Gastrointestinal Tract. In: Frick, P., von Harnack, GA., Martini, G.A., Prader, A. (eds) Ergebnisse der Inneren Medizin und Kinderheilkunde / Advances in Internal Medicine and Pediatrics. Ergebnisse der Inneren Medizin und Kinderheilkunde / Advances in Internal Medicine and Pediatrics, vol 45. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-67632-1_1

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-67632-1_1

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-67633-8

  • Online ISBN: 978-3-642-67632-1

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation