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Cardiovascular Effects of Drugs Acting on the Ventral Surface of the Brain Stem

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Central Interaction Between Respiratory and Cardiovascular Control Systems

Abstract

In 1958, that is nearly 20 years ago, Loeschcke and Koepchen (1) introduced the ventral surface of the brain stem as a site from which respiratory and circulatory effects were obtained by topical application of drugs or of solutions with different pH. Their experiments were mainly concerned with respiration, although blood pressure effects were described as well. Three distinct respiratory chemosensitive or thermosensitive zones were later localized at the ventral surface, the M, S and L zones, the letters standing for the names Mitchell, Schläfke and Loeschcke.

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References

  1. Loeschcke HH, Koepchen HP (1958) Versuch zur Lokalisation des Angriffsortes der Atmungs- und Kreislaufwirkung von Novocain im Liquor cerebrospinalis. Pfluegers Arch 266:628–641

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© 1980 Springer-Verlag Berlin Heidelberg

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Feldberg, W. (1980). Cardiovascular Effects of Drugs Acting on the Ventral Surface of the Brain Stem. In: Koepchen, H.P., Hilton, S.M., Trzebski, A. (eds) Central Interaction Between Respiratory and Cardiovascular Control Systems. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-67603-1_6

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  • DOI: https://doi.org/10.1007/978-3-642-67603-1_6

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-09948-2

  • Online ISBN: 978-3-642-67603-1

  • eBook Packages: Springer Book Archive

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