Skip to main content
SpringerLink
Log in

Measurement of Aortic and Mitral Regurgitation by Gated Cardiac Blood Pool Scans

  • Conference paper
Frontiers in Nuclear Medicine

  • 57 Accesses

Summary

A simple noninvasive radionuclide technique has been developed to measure the severity of valvular regurgitation. Right and left ventricular stroke volume indices (changes in counts between diastole and systole over the left and right ventricles) are obtained from 45° LAO gated cardiac blood pools scans. In 14 normal individuals, the left to right ventricular stroke index ratio was near unity (1.15 ±0.15 SD). In 26 patients with mitral and/or aortic regurgitation, it averaged 2.44 (range 1.36–5.30). Comparison between the stroke index ratio and qualitative angiographic estimates of regurgitation revealed good agreement (F=45.5,P<0.001). Our preliminary results indicate that gated cardiac blood pool scans permit noninvasive assessment of the severity of valvular regurgitation.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 84.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Reichek N, Shelburne JL, Perloff JK (1973) Clinical aspects of rheumatic valvular disease. Prog Cardiovasc Dis 15: 491–537

    Article  PubMed  CAS  Google Scholar 

  2. Wilierson JT, Kastor TA, Dinsmore RE, Mundth E, Buckley MJ, Austen WG, Sanders CA (1972) Non invasive assessment of mitral paravalvular and intravalvular regurgitation. Br Heart J 34: 561–568

    Article  Google Scholar 

  3. Sandler H, Dodge HT, Hay RE, Rackley CE (1963) Quantitation of valvular insufficiency in man by angiocardiography. Am Heart J 65: 501–513

    Article  PubMed  CAS  Google Scholar 

  4. Carlsonn E, Keene RJ, Lee P, Goerke RJ (1971) Angiocardiographic stroke volume correlation of the two cardiac ventricles in man. Invest Radiol 6: 44–51

    Article  Google Scholar 

  5. Austen WG, Edwards JE, Frye RL, Gensini GG, Gott VL, Griffith LSG, McGoon DC, Murphy ML, Roe BB (1975) A reporting system on patients evaluated for coronary artery disease. Circulation 51: 5A–40A

    Google Scholar 

  6. Sellers RD, Levy MJ, Amplatz K, Lillehei CW (1964) Left retrograde cardioangiography in acquired cardiac disease. Am J Cardiol 14: 437–447

    Article  PubMed  CAS  Google Scholar 

  7. Seeker-Walker RH, Resnick L, Kunz H, Parker JA, Hill RL, Potchen EJ (1973) Measurement of left ventricular ejection fraction. J Nucl Med 14: 798–802

    Google Scholar 

  8. Franklin DL, Van Citters RL, Rushmer RF (1962) Balance between right and left ventricular output. Circ Res 10: 17–26

    PubMed  CAS  Google Scholar 

  9. Rigo P, Murray M, Strauss HW, Pitt B (1974) Scintiphotographic evaluation of patients with suspected left ventricular aneurysm. Circulation 50: 985–991

    PubMed  CAS  Google Scholar 

  10. Burow RD, Strauss HW, Singleton T, Pond M, Rehn T, Bailey IK, Griffith LC, Nickoloff E, Pitt B (1977) Analysis of left ventricular function from multiple gated acquisition cardiac blood pool imaging. Circulation 56: 1024–1028

    PubMed  CAS  Google Scholar 

  11. Qureshi S, Wagner HN, Jr, Alderson PO, Housholder DF, Douglas KH, Lotter MG, Nickoloff EL, Tanabe M, Knowles LG (1978) Evaluation of left ventricular function in normal persons and in patients with heart diseases. J Nucl Med 19: 135–141

    PubMed  CAS  Google Scholar 

  12. Rackley LE, Hood WP, Jr (1973) Quantitative angiographic evaluation and pathophysiologic mechanisms in valvular heart disease. Prog Cardiovasc Dis 15: 427–447

    Article  PubMed  CAS  Google Scholar 

  13. Parker JA, Uren RF, Jones AG, Maddoy DE, Zimmerman RE, Neill JM, Holman BL (1977) Radionuclide ventriculography with the slant-hole collimator. J Nucl Med 18: 848–851

    PubMed  CAS  Google Scholar 

  14. Hegge FN, Hamilton QW, Larson SM, Ritchie JL, Richards P (1978) Cardiac chamber imaging: A comparison of red blood cells labeled with Tc-99m in vitro and in vivo. J Nucl Med 19: 129–134

    PubMed  CAS  Google Scholar 

  15. Carlsson E, Gross R, Holt RG (1977) The radiological diagnosis of cardiac valvular insufficiencies. Circulation 55: 921–933

    PubMed  CAS  Google Scholar 

  16. Lorch G, Rubenstein S, Baker D, et al (1977) Doppler echocardiography: Use of a graphical display system. Circulation 56: 576–585

    PubMed  CAS  Google Scholar 

  17. Morch JE, Klein SW, Richardson P (1972) Mitral regurgitation measured by continuous infusion of 133-xenon. Am J Cardiol 29: 812–816

    Article  PubMed  CAS  Google Scholar 

  18. Kirch DL, Metz CE, Steele PP (1974) Quantitation of valvular insufficiency by computerized radionuclide angiocardiography. Am J Cardiol 34: 711–721

    Article  PubMed  CAS  Google Scholar 

  19. Weber PM, Dos Remidios LV, Jasko IA (1972) Quantitative radioisotopic angiocardiography. J Nucl Med 13: 815 - 822

    PubMed  CAS  Google Scholar 

  20. Pierson RN, Jr, Alam S, Kemp HG, Friedman MI (1977) Radiocardiography in clinical cardiology. Semin Nucl Med 7: 85–100

    Article  PubMed  Google Scholar 

  21. Rigo P, Chevigne M (1980) Measurement of left to right shunts by gated cardiac blood pool scans: a new technigue. In: Hofer R, Bergmann H (eds) Radioaktive Isotope in Klinik und Forschung. Gasteiner Internationales Symposium, Vol 14

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Institute of Medicine, University of Liege, Belgium

    P. Rigo

  2. Division of Nuclear Medicine, The Johns Hopkins Medical Institutions, 601 N. Broadway Street, Baltimore, Maryland, 21205, USA

    P. O. Alderson, R. M. Robertson & L. C. Becker

  3. Division of Cardiology, The Johns Hopkins Medical Institutions, 601 N. Broadway Street, Baltimore, Maryland, 21205, USA

    P. O. Alderson, R. M. Robertson & L. C. Becker

Authors
  1. P. Rigo
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. P. O. Alderson
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. R. M. Robertson
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. L. C. Becker
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. Universitätsklinik und Poliklinik für Radioonkologie und Nuklearmedizin, Rämistraße 100, 8006, Zürich, Switzerland

    Wolfgang Horst

  2. Division of Nuclear Medicine, John Hopkins Medical Center, 615 North Wolfe Street, 212005, Baltimore, Maryland, USA

    Henry N. Wagner Jr.

  3. Division of Nuclear Medicine, John Hopkins Medical Institutions, 615 North Wolfe Street, 212005, Baltimore, Maryland, USA

    Julia W. Buchanan

  4. Division of Radiation Health, John Hopkins Medical Institutions, 615 North Wolfe Street, 212005, Baltimore, Maryland, USA

    Julia W. Buchanan

Rights and permissions

Reprints and permissions

Copyright information

© 1980 Springer-Verlag Berlin Heidelberg

About this paper

Cite this paper

Rigo, P., Alderson, P.O., Robertson, R.M., Becker, L.C. (1980). Measurement of Aortic and Mitral Regurgitation by Gated Cardiac Blood Pool Scans. In: Horst, W., Wagner, H.N., Buchanan, J.W. (eds) Frontiers in Nuclear Medicine. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-67575-1_21

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-67575-1_21

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-09895-9

  • Online ISBN: 978-3-642-67575-1

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation