Detection of Coronary Artery Disease by First Pass Radionuclide Exercise Testing
Anatomic lesions of a coronary artery do not always equate with the presence of a functional abnormality in the area of myocardium formerly supplied by the stenosed vessel . Even the muscle supplied by a totally occluded coronary artery may have adequate blood supply from collateral vessels. Although the myocardial blood supply in such cases may be adequate to meet the myocardial oxygen demand at rest, the blood supply may not be able to increase adequately to meet the increased myocardial oxygen demands during exercise stress. As a result, left ventricular dysfunction ensues [2,3].
KeywordsEjection Fraction Left Ventricular Function Exercise Stress Regional Wall Motion Significant Coronary Artery Disease
Unable to display preview. Download preview PDF.
- 2.Tennant R, Wiggers CJ (1935) The effect of coronary occlusion on myocardial contractions. Am J Physiol 112: 351Google Scholar
- 8.Jengo JA, Mena I, Blaufuss A, Criley JM (to be published) Evaluation of left ventricular function (ejection fraction and segmental wall motion) by single pass radioisotope angiography. CirculationGoogle Scholar
- 15.Paternac A, Gorlin R, Sonnenblick EH, Haft JI, Kemp HG (1972) Abnormalities of ventricular motion induced by atrial pacing in coronary artery disease. Circulation 45: 1195Google Scholar