The Frequency of Spontaneous Abortion After Discontinuance of Oral Contraceptives
We have observed over the past few years a sharp increase in the number of spontaneous abortions in which the embryo was abnormally developed, and we began searching our patients’ medical histories for possible causes. Realizing that either primary damage to the germ cell or the inability of the endometrium to act as a nidation bed can lead to these symptoms, we focused our attention on the various drugs that have a noxious effect on ovary and endometrium. The logical step, of course, was to look at oral contraceptives, the consumption of which has risen very rapidly over the past 10 years.
KeywordsOral Contraceptive Obstet Gynecol Spontaneous Abortion Primary Follicle Acta Obstet Gynecol
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