In Vitro Demyelination by Lymphocytes and Lymphokines from Patients and Experimental Animals

  • T. Yonezawa
  • N. Arizono
  • M. Hasegawa
  • Y. Yamamura
  • H. Miyaji
Conference paper

Abstract

Demyelinating change is a characteristic feature of demyelinating diseases. The mechanism involved has been thought to be cell-mediated immune processes characterized by activation of macrophages, which invade and phagocytize the myelin sheaths and the autophage of myelin debris in the myelin supporting cells. In addition, degenerative changes in sheaths, such as vesicular dissolution, are often observed.

Keywords

Cellulose Migration Toxicity Phenol Albumin 

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Copyright information

© Springer-Verlag Berlin Heidelberg 1980

Authors and Affiliations

  • T. Yonezawa
  • N. Arizono
  • M. Hasegawa
  • Y. Yamamura
  • H. Miyaji
    • 1
  1. 1.Department of PathologyKyoto Prefectural University of MedicineKyotoJapan

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