Plateau Waves: Production in the Rat and Simulation by Means of a Mechanical Model
The pressure increase of plateau waves (PW) is due to augmented cerebral blood volume (CBV) (4,7,8). Precapillary regulatory phenomena have been proposed as causative; we believe that this is incompatible with the size and the steepness of the pressure increase. We wish to demonstrate in a mechanical model and in experiments in the rat that an inhibition of venous drainage occurs due to a valve mechanism and that this model readiIy expIains PW.
KeywordsIntracranial Pressure Venous Drainage Cerebral Blood Volume Systemic Arterial Pressure Transverse Sinus
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