Abstract
The method available at present for the measurement of the pluripotential stem cells (CFUs) is based on the formation of the macroscopically visible colonies on the spleen surface of the lethally irradiated mice recipients of the bone marrow cell suspension [9]. This method demonstrates a fraction of the pluripotential stem cells injected [7].
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Hodgson, G. S., Bradley, T. R., Martin, R. F., Sumner, M., Fry, P.: Recovery of proliferating haemopoietic progenitor cells after killing by hydroxyurea. Cell Tissue Kinet. 8, 51–60 (1975)
Lajtha, L. G., Pozzi, L. V., Schofield, R., Fox, M.: Kinetic properties of haemopoietic stem cells. Cell Tissue Kinet. 2, 39–49 (1969)
Morse, B. S., Rencricca, N. J., Stohlman, F. jr.: The effect of hydroxyurea on differentiated marrow erythroid precursors. Proc. Soc. Exptl. Biol. Med. 130, 986–989 (1969)
Morse, B. S., Rencricca, N. J., Stohlman, F. jr.: Relationship of erythropoietic effectiveness to the generative cycle of erythroid precursor cell. Blood 35, 761–774 (1970)
Nečas, E., Neuwirt, J.: Control of haemopoietic stem cell proliferation by cells in DNA synthesis. Brit. J. Haemat. 33, 233–238 (1976)
Nečas, E., Ponka, P., Neuwirt, J.: Changes in stem cell compartments in mice after hydroxyurea. Cell Tissue Kinet. 11, 119–127 (1978)
Siminovitch, L., McCulloch, E. A., Till, J. E.: The distribution of colony — forming cells among the spleens colonies. J. cell. Physiol. 62, 327–336 (1963)
Terasima, T., Tolmach, L. J.: Growth and nucleic acid synthesis in synchronously dividing populations of Hela cells. Exp. Cell Res. 30, 344–352 (1963)
Till, J. E., McCulloch, E. A.: A direct measurement of the radiation sensitivity of normal mouse bone marrow cells. Radiat. Res. 14, 213–222 (1961)
Vassort, F., Winterholer, M., Frindel, E., Tubiana, M.: Kinetic parameters of bone marrow stem cells using in vivo suicide by tritiated thymidine or by hydroxyurea. Blood 41, 789–796 (1973)
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1979 Springer-Verlag Berlin Heidelberg
About this chapter
Cite this chapter
Nečas, E., Poňka, P., Neuwirt, J. (1979). Estimation of the Pluripotential Stem Cells in Bone Marrow After Hydroxyurea. In: Heimpel, H., Gordon-Smith, E.C., Heit, W., Kubanek, B. (eds) Aplastic Anemia. Haematology and Blood Transfusion / Hämatologie und Bluttransfusion, vol 24. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-67483-9_12
Download citation
DOI: https://doi.org/10.1007/978-3-642-67483-9_12
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-09772-3
Online ISBN: 978-3-642-67483-9
eBook Packages: Springer Book Archive