Abstract
There is a hierarchy of four levels on which one may talk about patterns in the immune system. The highest level concerns the morphology of the entire organ. Important as its detailed design may be in reality, I shall completely ignore it in the following. It is therefore sufficient, for the purpose of introduction, to give the very schematic picture shown in Fig. 1. The immune system consists of circulating lymphocytes, antibody molecules, and various accessory components such as macrophages and complement.
This is a preview of subscription content, log in via an institution.
Buying options
Tax calculation will be finalised at checkout
Purchases are for personal use only
Learn about institutional subscriptionsPreview
Unable to display preview. Download preview PDF.
References
“Origin of Lymphocyte Diversity,” Cold Spring Harbor Symposium on Quantitative Biology 41 (1976). Cold Spring Harbor Lab. 1977
R.J. Poljak, L.M. Amzel, H.P. Avey, B.L. Chen, R.P. Phizackerley, F. Saul, Three-dimensional structure of the Fab’ fragment of a human immunoglobulin at 2.8 Å resolution. Proc. Nat. Acad. Sci. (USA) 70, 3305 – 3310 (1973).
F.M. Burnet. A modification of Jerne’s theory of antibody production using the concept of clonal selection. Austr. J. Sci. 20, 67 – 68 (1957).
N.K. Jerne. Towards a network theory of the immune system. Ann. Immunol. Inst. Pasteur 125C, 373 – 389 (1974).
N.K. Jerne. The Immune System. A web of V-domains. In: The Harvey Lectures 70, Academic Press, New York 1976.
P.H. Richter. A network theory of the immune response. Eur. J. Immunol. 5, 350 – 354 (1975).
P.H. Richter. The network idea and the immune response. In: “Theoretical Immunology,” Eds. G.I. Bell, A.S. Perelson, G.H. Pimbley. Dekker, New York, 1978.
D.W. Dresser, N.A. Mitchison. The Mechanism of immunological paralysis. Adv. Immunol. 8, 129 – 181 (1968).
P. Bretscher, M. Cohn. A theory of self-nonself discrimination. Science 169, 1042 – 1049 (1970).
P.H. Richter. Pattern formation in the immune system. Lect. on Math, in the Life Sciences 11, 89 – 107 (1979).
G.W. Siskind, B. Benacerraf. Cell selection by antigen in the immune response. Adv. Immunol. 10, 1 – 50 (1969).
J. Tiedge. Netzwerktheorie für Selektionsvorgänge in der Immunantwort. Diplomarbeit Marburg (Institut f. Theor. Physik) (1976).
S. Fazekas, de St. Groth, R.G. Webster. Disquisitions on original antigenic sin. J. Exp. Med. 124, 331 – 361 (1966).
H.R. Wilson. Cooperative phenomena in a homogeneous cortical tissue model. In “Synergetics. Cooperative phenomena in multi-component systems.” (H. Haken, Ed.) Teubner, Stuttgart 1973.
R.K. Gershon. T cell regulation: the “second law of thymodynamics.” In “The Immune System — Genes, Receptors, Signals.” (E.F. Sercarz, A.R. Williamson, CF. Fox Eds.) Academic Press, New York 1974.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1979 Springer-Verlag Berlin Heidelberg
About this paper
Cite this paper
Richter, P.H. (1979). Patterns in the Immune System. In: Haken, H. (eds) Pattern Formation by Dynamic Systems and Pattern Recognition. Springer Series in Synergetics, vol 5. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-67480-8_15
Download citation
DOI: https://doi.org/10.1007/978-3-642-67480-8_15
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-67482-2
Online ISBN: 978-3-642-67480-8
eBook Packages: Springer Book Archive