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Anaphylactic Shock Syndrome

  • A. Wegmann
  • H. Renker
  • L. Nordström
  • L. Mandaus
  • K. Pavek
Conference paper
Part of the Anaesthesiologie und Intensivmedizin / Anaesthesiology and Intensive Care Medicine book series (A+I, volume 125)

Zusammenfassung

As „anaphylactic reaction“ part of which is the anaphylactic shock syndrome, we understand a series of organ reactions due to anaphylactic antibodies which will rarely be present altogether in a single case. They include:
  1. 1.

    Peripheral blood pooling resulting in decreased blood return to the right heart

     
  2. 2.

    Inconstant changes in peripheral arterial resistance (first decreased, later increased)

     
  3. 3.

    Increased pulmonary arterial resistance resulting in decreased blood return to the left heart

     
  4. 4.

    Depression of myocardial contractility

     
  5. 5.

    Decreased coronary blood flow

     
  6. 6.

    Electrocardiographic changes mainly consisting in ST-T depression and possibly av-blocks and ventricular extrasystolies

     
  7. 7.

    Bronchiolar constriction

     
  8. 8.

    Laryngospasm

     
  9. 9.

    Acidosis

     
  10. 10.

    Increase of vascular permeability

     
  11. 11.

    Hemoconcentration

     
  12. 12.

    Blood platelet aggregation

     
  13. 13.

    Decrease of lung compliance

     
  14. 14.

    Decrease of arterial oxygen saturation

     

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References

  1. 1.
    Capurro, N., Levi, R.: The heart as a target organ in systemic allergic reactions comparison of cardiac anaphylaxis in vivo and in vitro. Circ. Res. 36, 520–528 (1975)PubMedGoogle Scholar
  2. 2.
    Fisher, M.: Blood volume replacement in acute anaphylactic cardiovascular collapse related to anaesthesia. Brit. J. Anaesth. 49, 1023–1026 (1977)PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1980

Authors and Affiliations

  • A. Wegmann
  • H. Renker
  • L. Nordström
  • L. Mandaus
  • K. Pavek

There are no affiliations available

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