Fungal Viruses pp 120-128 | Cite as

Fungal Viruses and Killer Factors — Ustilago maydis Killer Proteins

  • Y. Koltin
  • R. Levine
Conference paper
Part of the Proceedings in Life Sciences book series (LIFE SCIENCES)

Abstract

In studies on the genetics and biochemistry of the host—virus interactions, as in many other biological phenomena, the preferred systems are those with a short generation time in which biochemistry and genetics can be studied simultaneously. The fungi, as a relatively simple group of eukaryotic organisms, have played a prominent role in basic research on the genetic expression at the cellular level (Beadle and Tatum, 1941; Beadle, 1946) as a model system that is amenable to both genetic and biochemical analysis. However, in all the research on virus—host interactions the fungi stand out as a unique group in which little reference to viruses was ever made. Numerous extrachro-mosomally inherited phenomena in fungi have been reported, such as unstable somatic segregation (Arlett et al., 1962; Grindle, 1964; Jinks, 1966), senescence (Marcou and Schecroun, 1969), vegetative death (Jinks, 1959), and even plaque formation (Koltin et al., 1973). However, the presence of viruses in the fungi was shown clearly only in the early 1960’s.

Keywords

Cellulose Sucrose Corn fIltration Acetone 

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References

  1. Arlett CF, Grindle M, Jinks JL (1962) The “red” cytoplasmic variant of Aspergillus nidulans Heredity 17:197–209PubMedCrossRefGoogle Scholar
  2. Beadle GW (1946) Genes and the chemistry of the organism. Am Sci 34:31–53PubMedGoogle Scholar
  3. Beadle GW, Tatum EL (1941) Genetic control of biochemical reactions in Neurospora Proc Natl Acad Sci USA 27:499–506PubMedCrossRefGoogle Scholar
  4. Burnett JH (1975) Mycogenetics. John Wiley and Sons, LondonGoogle Scholar
  5. Davis BJ (1964) Disc electrophoresis. II. Method and application to human serum proteins. Ann NY Acad Sci 121:404–427PubMedCrossRefGoogle Scholar
  6. Day PR, Anagnostakis SL (1973) The killer system in Ustilago maydis: Heterokaryon transfer and loss of determinants. Phytopathology 63:1017–1018CrossRefGoogle Scholar
  7. Day PR, Dodds JA (1979) Viruses of plant pathogenic fungi. In: Lemke PA (ed) Viruses and Plasmids in fungi. Dekker, New YorkGoogle Scholar
  8. Grindle M (1964) Nucleo-cytoplasmic interactions in the “red” cytoplasmic variant of Aspergillus nidulans Heredity 19:75–95PubMedCrossRefGoogle Scholar
  9. Hankin L, Puhalla JE (1971) Nature of a factor causing interstrain lethality in Ustilago may dis Phytopathology 61:50–53CrossRefGoogle Scholar
  10. Hardy KG (1975) Colicinogeny and related phenomena. Bacteriol Rev 39:464–515PubMedGoogle Scholar
  11. Holland IB (1975) Physiology of colicin action. Adv Microbiol Physiol 12:55–139CrossRefGoogle Scholar
  12. Jinks JL (1959) Lethal suppressive cytoplasm in aged clones of Aspergillus glaucus J Gen Microbiol 21:397–409Google Scholar
  13. Jinks JL (1964) Extrachromosomal inheritance. Prentice-Hall, Inc, Englewood Cliffs, New Jersey Jinks JL (1966) In: Ainsworth GL, Sussman AS (eds) The fungi, vol II, pp 619–660. Academic Press, New YorkGoogle Scholar
  14. Kandel J, Koltin Y (1978) Killer phenomenon in Ustilago maydis: comparison of the killer proteins. Exp Mycol 2:270–278CrossRefGoogle Scholar
  15. Koltin Y (1977) Virus-like particles in Ustilago maydis: mutants with partial genomes. Genetics 86: 527–534PubMedGoogle Scholar
  16. Koltin Y, Day PR (1975) Specificity of Ustilago maydis killer proteins. Appl Microbiol 30:694–696PubMedGoogle Scholar
  17. Koltin Y, Day PR (1976a) Inheritance of killer phenotypes and double stranded RNA in Ustilago maydis Proc Natl Acad Sci USA 73:594–598PubMedCrossRefGoogle Scholar
  18. Koltin Y, Day PR (1976b) Suppression of the killer phenotype in Ustilago maydis Genetics 82: 629–637PubMedGoogle Scholar
  19. Koltin Y, Kandel JS (1978) Killer phenomenon in Ustilago maydis: the organization of the viral genome. Genetics 88:267–276PubMedGoogle Scholar
  20. Koltin Y, Berick R, Stamberg J, Ben-Shaul Y (1973) Virus-like particles and cytoplasmic inheritance of plaques in a higher fungus. Nature New Biol 241:108–109PubMedGoogle Scholar
  21. Koltin Y, Mayer I, Steinlauf R (in press) Killer phenomenon in Ustilago maydis Mapping viral functions. Mol Gen GeneticsGoogle Scholar
  22. Lemke PA (1976) Viruses of eukaryotic microorganisms. Annu Rev Microbiol 30:105–145PubMedCrossRefGoogle Scholar
  23. Lemke PA, Nash CH (1974) Fungal viruses. Bacteriol Rev 38:29–56PubMedGoogle Scholar
  24. Marcou D, Schecroun J (1959) La sénescence chez Podospora anserina pourrait être due à des particules cytoplasmiques infectantes. C R Acad Sci (Paris) Ser-D 248:280–283Google Scholar
  25. Meselson M, Yuan R, Heywood J (1972) Restriction and modification of DNA. Annu Rev Biochem 41:442–466CrossRefGoogle Scholar
  26. Ornstein L (1964) Disc electrophoresis. I. Background and theory. Ann NY Acad Sci 121:321–349PubMedCrossRefGoogle Scholar
  27. Puhalla JE (1968) Compatibility reactions on solid medium and interstrain inhibition in Ustilago maydis Genetics 60:461–475PubMedGoogle Scholar
  28. Somers JM, Bevan EA (1969) The inheritance of the killer character in yeast. Genet Res (Camb) 13:71–83CrossRefGoogle Scholar
  29. Wickner RB (1976) Killer of Saccharomyces cerevisiae: a double stranded ribonucleic acid plasmid. Bacteriol Rev 40:757–773PubMedGoogle Scholar
  30. Wood HA, Bozarth RF (1973) Heterokaryon transfer of virus-like particles associated with a cyto-plasmically inherited determinant in Ustilago maydis Phytopathology 63:1019–1021CrossRefGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1979

Authors and Affiliations

  • Y. Koltin
    • 1
  • R. Levine
    • 1
  1. 1.Department of Microbiology, Faculty of Life SciencesUniversity of Tel-AvivRamat AvivIsrael

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