Skip to main content

Experimental Cancer of the Gastric Stump

  • Conference paper
Gastric Cancer

Abstract

During the last 5 years, carcinoma of the gastric stump has become a well-known clinical entity. It refers to a carcinoma occurring in the gastric remnant after partial resection for benign disease. To rule out the presence of an occult carcinoma at the time of the original resection, a time interval of at least 5 years should have elapsed since operation. The available data indicate that, when 20 – 25 years have passed since resection, the risk of development of a stump carcinoma is increased and steadily increasing [1, 6, 19, 20]. Therefore, the threat of this late complication of a stomach resection has influenced substantially the trends of modern gastric surgery promoting the breakthrough of more conservative procedures, such as vagotomy, in the treatment of peptic ulcer.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 84.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Clémencon, G., Baumgartner, R., Leuthold, E., Miller, G., Neiger, A.: Das Karzinom des operierten Magens. Dtsch. Med. Wochenschr. 101, 1015–1020 (1976)

    Article  PubMed  Google Scholar 

  2. Craddock, V. M.: The reaction of N-methyl-N’-nitro-N-nitrosoguanidine with deoxyribonucleic acid. Biochem. J. 106, 921–922 (1968)

    PubMed  CAS  Google Scholar 

  3. Dahm, K., deHeer, K.: Cancer risk of the stomach resected for ulcer: The role of duodenogastric reflux. Z. Krebsforsch. 87, 343–344 (1976)

    Article  Google Scholar 

  4. Dahm, K., Werner, B.: Experimentelles Anastomosencarcinom. Ein Beitrag zur Pathogenese des Magenstumpfcarcinoms. Langenbecks Arch. Chir. 333, 211–236 (1973)

    Article  PubMed  CAS  Google Scholar 

  5. Dahm, K., Eichen, R., Mitschke, H.: Das Krebsrisiko im Resektionsmagen. Zur Bedeutung des duodenogastrischen Refluxes bei verschiedenen gastroenteralen Anastomosen. Langenbecks Arch. Chir. 344, 71–82(1977)

    Article  PubMed  CAS  Google Scholar 

  6. Domellöf, L., Januger, K.-G.: The risk for gastric carcinoma after partial gastrectomy. Am. J. Surg. 134, 581–584(1977)

    Article  PubMed  Google Scholar 

  7. Domellöf, Eriksson, S., Januger, K.-G.: Carcinoma and possible precancerous changes of the gastric stump after Billroth II resection. Gastroenterology 73, 462–468 (1977)

    PubMed  Google Scholar 

  8. Grundmann, E.: Histologic types and possible initial stages in early gastric carcinoma. Beitr. Pathol. 154, 256–280(1975)

    PubMed  CAS  Google Scholar 

  9. Hammar, E.: The localization of precancerous changes and carcinoma after previous gastric operation for benign condition. Acta Pathol. Microbiol. Scand. (A) 84, 495–507 (1976)

    CAS  Google Scholar 

  10. Hilbe, G., Salzer, G. M., Hussl, H., Kutschera, H.: Die Carcinomgefährdung des Resektionsmagens. Langenbecks Arch. Klin. Chir. 323, 142–153 (1968)

    Article  CAS  Google Scholar 

  11. Kühlmayer, R., Rokitansky, O.: Das Magenstumpfcarcinom als Spätproblem der Ulcuschirurgie. Langenbecks Arch. Klin. Chir. 278, 361–375 (1954)

    Article  Google Scholar 

  12. Laurén, P.: The two histological main types of gastric carcinoma: diffuse and so-called intestinal-type carcinoma. An attempt at a histo-clinical classification. Acta Pathol. Microbiol. Scand. 64, 31–49(1965)

    PubMed  Google Scholar 

  13. McCalla, D. R.: Reaction of N-methyl-N’-nitro-N-nitroguanidine and N-methyl-N′-nitroso-p-toluenesulfonamide with DNA in vitro. Biochim. Biophys. Acta 155, 114–120 (1968)

    PubMed  CAS  Google Scholar 

  14. Mitschke, H.: Pathologisch-anatomische Grundlagen der Krebsrisikoerkrankungen und des Frühcarcinoms des Magens. Chirurg 49, 465–472 (1978)

    PubMed  CAS  Google Scholar 

  15. Oehlert, W., Keller, P., Henke, M., Strauch, M.: Die Dysplasien der Magenschleimhaut. Das Problem ihrer klinischen Bedeutung. Dtsch. Med. Wochenschr. 100, 1950–1956 (1975)

    Article  PubMed  CAS  Google Scholar 

  16. Rumpf, P., Schacht, U., Palomba, P., Kremer, K., Schmitz, H., Borchard, F.: Chemisch induzierte Karzinogenese des Rattenmagens nach Vagotomie und Resektion. Z. Gastroenterol. 16, 85–94(1978)

    PubMed  CAS  Google Scholar 

  17. Saito, T., Inokuchi, K., Takayama, S., Sugimura, T.: Sequential morphological changes in N-methyl-N’-nitro-N-nitrosoguanidine carcinogenesis in the glandular stomach of rats. J. Natl. Cancer Inst. 44, 769–783 (1970)

    PubMed  CAS  Google Scholar 

  18. Schlag, P., Meister, H., Feyerabend, G., Merkle, P.: Der Einfluß des duodenogastrischen Refluxes auf das Epithel an der gastroenteralen Anastomose. Eine experimentelle Untersuchung. Langenbecks Arch. Chir. 344, 207–217 (1977)

    Article  PubMed  CAS  Google Scholar 

  19. Schmid, E., Vollmer, R., Adlung, J., Blaich, E., Goebell, H., Heinkel, K., Kimmig, J.-M., Probst, M.: Zur endoskopischen Diagnostik des Karzinoms im operierten Magen. Z. Gastroenterol. 14, 521–530(1976)

    PubMed  CAS  Google Scholar 

  20. Stalsberg, H., Taksdal, S.: Stomach cancer following gastric surgery for benign conditions. Lancet 1971 II, 1175–1177

    Article  Google Scholar 

  21. Stewart, H. L., Snell, K. C., Morris, H. P., Wagner, B. P., Ray, F. E.: Carcinoma of the glandular stomach of rats ingesting N,N’-2,7-fluorenylenebisacetamide. Nat. Cancer Inst. Monogr. 5, 105–139(1961)

    Google Scholar 

  22. Sugimura, T., Fujimura, S., Baba, T.: Tumor production in the glandular stomach and alimentary tract of the rat by N-methyl-N’-nitro-N’-nitrosoguanidine. Cancer Res. 30, 455–465 (1970)

    PubMed  CAS  Google Scholar 

  23. Werner, B., Leppin, A., Seiler, I., Mitschke, H., Soehendra, N., Farthmann, E., Rehner, M., Dahm, K.: Duodenaler Reflux und Gastritis im Billroth I Magen. Dtsch. Med. Wochenschr. 100, 2385–2388(1975)

    Article  PubMed  CAS  Google Scholar 

Download references

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1979 Springer-Verlag Berlin Heidelberg

About this paper

Cite this paper

Dahm, K., Werner, B., Eichen, R., Mitschke, H. (1979). Experimental Cancer of the Gastric Stump. In: Herfarth, C.H., Schlag, P.M. (eds) Gastric Cancer. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-67368-9_7

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-67368-9_7

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-67370-2

  • Online ISBN: 978-3-642-67368-9

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics