Skip to main content
SpringerLink
Log in
Book cover

Gastric Cancer pp 129–136Cite as

Risk of Carcinoma in the Gastric Remnant After Gastric Resection for Benign Conditions

  • Conference paper

Abstract

Up to 1950, carcinoma of the gastric remnant after resection for a benign lesion seemed to be a rare disease. Morgenstern et al. [25] estimated the number of patients with cancer of the gastric stump mentioned in the world literature up to the year 1972 to be about 1100. Kühlmayer and Rokitansky [22] collected among 50000 autopsies at the Institute of Pathology of the University of Vienna, 363 cases with gastric resections type Billroth I, Billroth II, or gastroenterostomies and found 40 cancers in this material. This corresponds to an incidence of 11% compared to 5.3% gastric cancers in nonoperated stomachs among the 49637 other autopsies. Hilbe et al. [17] found in their necropsy material 5.4% cancers among nonoperated stomachs, but a frequency double as high in resected stomachs. Stalsberg and Taksdal [39] report that among 630 cases of gastric cancer, the frequency of previous gastric surgery for benign conditions, 25 years or more before death, was six times the frequency among matched controls. Even if one objects that necropsy material is biased by preselection in some way, one cannot deny the higher incidence of gastric stump cancer. There are few prospective studies based on endoscopically examined patients. From 1968 to 1974, Pesendorfer et al. [29] found 16% gastric stump cancers among their patients with resected stomachs. Schmid et al. [35] evaluated 24000 gastroscopies and found 609 patients with gastrojejunostomy, after an interval of at least 5 years after gastric resection, 39 of them had gastric stump cancer (6.4%).

This is a preview of subscription content, log in via an institution.

Chapter
USD   29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD   84.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD   109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Learn about institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Bürgi, W., Kaufmann, H., Clémençon, G.: Isolierung, Identifizierung und quantitative Bestimmung von Lysolecithin im menschlichen Magensaft. Schweiz. Med. Wochenschr. 105, 1814–1819(1975)

    PubMed  Google Scholar 

  2. Clémençon, G., Baumgartner, R., Leuthold, E., Miller, G., Neiger, A.: Das Karzinom des operierten Magens. Dtsch. Med. Wochenschr. 101, 1015–1020 (1976)

    Article  PubMed  Google Scholar 

  3. Clémençon, G., Bürgi, W.: Hämolysierende Substanzen im Magensekret, Häufigkeit des Lysolecithin-Nachweises. Schweiz. Med. Wochenschr. 107, 952–956 (1977)

    PubMed  Google Scholar 

  4. Clémençon, G., Bürgi, W., Kaufmann, H.: Lysolecithin im nächtlichen Magensekret (Abstrakt). 1st Congress of the society for Gastroenterology in Bavaria 24–25 October 1973

    Google Scholar 

  5. Clémençon, G., Gloor, F.: Ist die chronisch atrophische Gastritis eine Präkanzerose? (in press)

    Google Scholar 

  6. Correa, P., Haenszel, W., Cuello, C., Tannenbaum, St., Archer, M.: A model for gastric cancer epidemiology. Lancet 1975 II, 58 – 59

    Article  Google Scholar 

  7. Dahm, K., Werner, B.: Das Karzinom im operierten Magen. Dtsch. Med. Wochenschr. 100, 1073–1078(1975)

    Article  PubMed  CAS  Google Scholar 

  8. Davenport, H. W.: Destruction of the gastric mucosal barrier by detergents and urea. Gastroenterology 54, 175–181 (1968)

    PubMed  CAS  Google Scholar 

  9. Davenport, H. W.: Effect of lysolecithin, digitonin and phospholipase A upon the dog’s gastric mucosal barrier. Gastroenterology 59, 505–509 (1970)

    PubMed  CAS  Google Scholar 

  10. Domellöf, L., Eriksson, S., Janungen, K. G.: Carcinoma and possible precancerous changes of the gastric stump after Billroth II resection. Gastroenterology 73, 462–468 (1977)

    PubMed  Google Scholar 

  11. Du Plessis, D. J.: Gastric mucosal changes after operations on the stomach. S. Afr. Med. J. 36, 471–478(1962)

    Google Scholar 

  12. Gerstenberg, E., Albrecht, A., Krentz, K., Voth, H.: Das Magenstumpfkarzinom: Eine Spätkomplikation des operierten Magens? Dtsch. Med. Wochenschr. 90, 2185–2190 (1965)

    Article  PubMed  CAS  Google Scholar 

  13. Gjeruldsen, S. T., Myren, J., Fretheim, B.: Alterations of gastric mucosa following a graded partial gastrectomy for duodenal ulcer. Scand. J. Gastroenterol. 3, 465–470 (1968)

    Article  PubMed  CAS  Google Scholar 

  14. Grant, R., Grossmann, M. J., Wang, K. J., Jvy, A. C.: The cytolytic action of some gastrointestinal secretions and enzymes on epithelial cells of the gastric and duodenal mucosa. J. Cell. Comp. Physiol. 37, 137–161 (1951)

    Article  CAS  Google Scholar 

  15. Griesser, G., Schmidt, H.: Statistische Erhebungen über die Häufigkeit des Karzinoms nach Magenoperation wegen eines Geschwürleidens. Med. Welt 15, 1836–1840 (1964)

    Google Scholar 

  16. Hammar, E.: The localization of precancerous changes and carcinoma after previous gastric surgery for benign condition. Acta Pathol. Microbiol. Scand. (A) 84, 495–504 (1976)

    CAS  Google Scholar 

  17. Hübe, G., Salzer, G. M., Hussl, H., Kutschera, H.: Die Carcinomgefährdung des Resektionsmagens. Langenbecks Arch. Klin. Chir. 323, 142 (1968)

    Article  Google Scholar 

  18. Johnson, A. G., McDermott, J. S.: Lysolecithin: A factor in the pathogenesis of gastric ulceration? Gut 15, 710 (1974)

    Article  PubMed  CAS  Google Scholar 

  19. Jvey, K. J., Den Besten, L., Clifton, J. A.: Effect of bile salts on ionic movement across the human gastric mucosa. Gastroenterology 59, 683–690 (1970)

    Google Scholar 

  20. Kobayashi, S., Prolla, J. C., Kirsner, J. B.: Late gastric carcinoma developing after surgery for benign conditions. Am. J. Dig. Dis. 15, 905–912 (1970)

    Article  PubMed  CAS  Google Scholar 

  21. Krause, U.: Late prognosis after partial gastrectomy for ulcer. Acta. Chir. Scand. 114, 341 – 354 (1957)

    Google Scholar 

  22. Kühlmayer, R., Rokitansky, O.: Das Magenstumpfcarcinom als Spätproblem der Ulcuschirurgie. Langenbecks Arch. klin. Chir. 278, 361–375 (1954)

    Article  Google Scholar 

  23. Lawson, H. H.: Effect of duodenal contents on the gastric mucosa under experimental conditions. Lancet 1964 I, 469–472

    Article  Google Scholar 

  24. Miller, G.: personal communication 1978

    Google Scholar 

  25. Morgenstern, L., Yamakawa, T., Seltzer, D.: Carcinoma of the gastric stump. Amer. J. Surg. 125, 29–38(1973)

    Article  PubMed  CAS  Google Scholar 

  26. Oehlert, W., Keller, P., Henke, M., Strauch, M.: Die Dysplasien der Magenschleimhaut. Dtsch. Med. Wochenschr. 100, 1950–1956 (1975)

    Article  PubMed  CAS  Google Scholar 

  27. Osnes, M., Løtveil, T., Myren, J., Serek-Hansen, A.: Early gastric carcinoma in patients with a Billroth II partial gastrectomy. Endoscopy 9, 45–49 (1977)

    Article  PubMed  CAS  Google Scholar 

  28. Palmer, E. D.: Gastritis. A revaluation. Medicine (Baltimore) 33, 199–290 (1954)

    Article  PubMed  CAS  Google Scholar 

  29. Pesendorfer, F. X., Afschar, S., Henschel, E., Weiss, W.: Das Magenstumpfcarcinom aus endoskopischer Sicht. Fortschr. Gastroenterol. Endoskopie 117–121 (1974)

    Google Scholar 

  30. Pötzi, R., Pesendorfer, F. X., Denk, H., Wewalka, F.: Makroskopische und histologische Befunde am operierten Magen. Z. Gastroenterol. 15, 627–629 (1977)

    PubMed  Google Scholar 

  31. Rehner, M., Soehendra, N., Eichfuss, H. P., Dahm, K., Eckert, P., Mitschke, H.: Frühkarzinome im (Billroth-II-)Resektionsmagen. Dtsch. Med. Wochenschr. 99, 533–534 (1974)

    PubMed  CAS  Google Scholar 

  32. Reynolds, K. W., Johnson, A. G., Fox, B.: Is intestinal metaplasia of the gastric mucosa a pre-malignant lesion? Clin. Oncol. 1, 101 – 109 (1975)

    PubMed  CAS  Google Scholar 

  33. Schell, R. F., Dockerty, M. B., Comfort, M. W.: Carcinoma of the stomach associated with pernicious anemia. Surg. Gynecol. Obstet. 98, 710–720 (1954)

    PubMed  CAS  Google Scholar 

  34. Schindler, R.: Gastritis. New York: Grune & Stratton 1947

    Google Scholar 

  35. Schmid, E., Vollmer, R., Adlemg, J., Blaich, E., Goebell, H., Heinkel, K., Kimmig, J. M., Probst, M.: Zur endoskopischen Diagnose des Karzinoms im operierten Magen. Z. Gastroenterol. 14, 521–530(1976)

    PubMed  CAS  Google Scholar 

  36. Seifert, E., Dittrich, H., Erd, W.: Gastrobioptische Untersuchung am Resektionsmagen. Med. Welt 17, 38–44(1966)

    Google Scholar 

  37. Shearmann, D. J. C., Finlayson, N. D. C., Wilson, R., Samson, R. R.: Carcinoma of the stomach and early pernicious anaemia. Lancet 1966 II, 403 – 405

    Article  Google Scholar 

  38. Simon, L., Figus, A. J., Bajtai, A.: Chronic gastritis following resection of the stomach. Am. J. Gastroenterol. 60, 477–487 (1973)

    PubMed  CAS  Google Scholar 

  39. Stalsberg, H., Taksdal, S.: Stomach cancer following gastric surgery for benign conditions. Lancet 1971 II, 1175–1177

    Article  Google Scholar 

  40. Thompson, H.: Gastritis in partial gastrectomy specimens. Gastroenterology 36, 861 – 876 (1959)

    PubMed  CAS  Google Scholar 

Download references

Authors
  1. G. Clémençon
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. Department für Chirurgie der Universität, Steinhövelstraße 9, 7900, Ulm, Federal Republic of Germany

    Christian H. Herfarth  & Peter M. Schlag  & 

Rights and permissions

Reprints and permissions

Copyright information

© 1979 Springer-Verlag Berlin Heidelberg

About this paper

Cite this paper

Clémençon, G. (1979). Risk of Carcinoma in the Gastric Remnant After Gastric Resection for Benign Conditions. In: Herfarth, C.H., Schlag, P.M. (eds) Gastric Cancer. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-67368-9_18

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-67368-9_18

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-67370-2

  • Online ISBN: 978-3-642-67368-9

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation