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Proteine, die mit Nukleinsäuren in Wechselwirkung treten

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Molekular- und Zellbiologie
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Zusammenfassung

Regulatorproteine binden an DNS und beeinflussen die spezifische Genexpression (→ Transkriptionsrate). Dir Einfluß ist entweder negativ oder positiv. Proteine mit negativem Einfluß bezeichnet man als Repressoren. Der Lac-Repressor von Escherichia coli ist das bestuntersuchte Beispiel hierfür. Zu den aktivierenden Proteinen gehört das CAP (Cyclisches AMP-bindendes Protein), welches ebenfalls auf den Lac-Operator (s. Kap. 9) einwirkt. Bei Prokaryonten ist eine Reihe weiterer Operons bekannt und eingehend studiert worden, allerdings sind unsere Kenntnisse über die DNS dabei um etliches besser als das Wissen über die ebenfalls essentiellen Proteine.

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von Sengbusch, P. (1979). Proteine, die mit Nukleinsäuren in Wechselwirkung treten. In: Molekular- und Zellbiologie. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-67358-0_19

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  • DOI: https://doi.org/10.1007/978-3-642-67358-0_19

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-67359-7

  • Online ISBN: 978-3-642-67358-0

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