Ultrasonic Disruption of Bacteria and Density-Gradient Centrifugation of the Products

  • Alois Nowotny


In addition to those mechanical procedures which disrupt cells by grinding them with solid particles, such as sand or small glass beads, the most widely applied is the destruction of cells by ultrasonication.


Sucrose Convection Foam Titration Sedimentation 


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. Britten, R. J., Roberts, R.B.: Science 131, 32 (1960)PubMedCrossRefGoogle Scholar
  2. Hughes, D.E., Nyborg, W.L.: Science 138, 108 (1962)PubMedCrossRefGoogle Scholar
  3. Lindstroem, O.: J. acoust. Soc. Amer, 27, 654 (1955)CrossRefGoogle Scholar
  4. Meselson, M., Stahl, F.W., Vinograd, J.: Proc. Nat. Acad. Sci (USA) 43, 581 (1957)CrossRefGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1979

Authors and Affiliations

  • Alois Nowotny
    • 1
  1. 1.University of PennsylvaniaPhiladelphiaUSA

Personalised recommendations