Skip to main content

Design of the Pennsylvania State University Artificial Heart and Electronic Automatic Control System

  • Chapter
Assisted Circulation

Abstract

Almost 20 years have passed since publication of the first report of implantation of an artificial heart in an experimental animal [1]. A review of the literature to date indicates that a quantum jump in progress has been made over the past 5 years. Reported survival times have increased from only a few days to several months, and the overall condition of experimental animals undergoing total heart replacement has greatly improved. The major factor responsible for this progress has not been the development of any major new technology, but rather the assimilation of knowledge gained in previous years. This knowledge was a prerequisite for increasing survival times. The progress toward developing a practical therapeutic device continues to be significant. Although various technical and financial problems create transient lags in progress, a review of the history of total artificial heart (TAH) development leaves one very optimistic.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 84.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Akutsu, T., Kolff, W. J.: Permanent substitutes for valves and hearts. Trans. Am. Soc. Artif. Intern. Organs 4, 230–232 (1958)

    Google Scholar 

  2. Arrowood, J. A., Shah, R., Brighton, J. A. et al.: An in vitro evaluation of erythrocyte bulk lysis produced by a pulsatile blood pump. 29th Ann. Conf. Eng. Med. Biol. (1976)

    Google Scholar 

  3. Heimlich, L., Christiansen, V., Sato, T.: Energy transmission through intact skin, Ch. 79. Hegyeli, R. J. (ed.), pp. 937–945. Artificial Heart Program Conference Proceedings. Washington, D. C.: United States Printing Office 1969

    Google Scholar 

  4. Kasai, S., Koshino, I., Washizu, N. et al.: Is progressive anemia inherent to total artificial heart recipients. Trans. Am. Soc. Artif. Intern. Organs 22, 489–496 (1976)

    PubMed  CAS  Google Scholar 

  5. Kolff, W. J.: Artificial organs, pp. 13–16. New York: John Wiley & Sons 1976

    Google Scholar 

  6. Landis, D. L., Pierce, W. S., Rosenberg, G. et al.: Long term in vivo automatic electronic control of the artificial heart. Trans. Am. Soc. Artif. Intern. Organs 23, 214 (1977)

    Google Scholar 

  7. O’Bannon, W., Donachy, J. H., Brighton, J. A. et al.: Design and evaluation of a prosthetic ventricle: A tethered sac pump fabricated of segmented polyurethane. Ann. Conf. Eng. Med. Biol. 17, 440 (1975)

    Google Scholar 

  8. Olsen, D., Van Kampen, K., Voider, J. et al.: Pulmonary hepatic and renal pathology associated with an artificial heart. Trans. Am. Soc. Artif. Intern. Organs 19, 518–582 (1973)

    Google Scholar 

  9. Pae, W., Jr., O’Bannon, W., Prophet, G. A. et al.: Design and evaluation of a percutaneous transthoracic cannula. Trans. Am. Soc. Artif. Intern. Organs 22, 135–141 (1976)

    PubMed  Google Scholar 

  10. Patterson, S. W., Pipet, H., Starling, E. H.: The regulation of the heart beat. J. Physiol. 48, 465–513 (1914)

    PubMed  CAS  Google Scholar 

  11. Phillips, W. M., Lenker, J. A., Brighton, J. A. et al.: Row visualization methods for in vitro cardiovascular flow studies. Proc. Annu. Conf. Eng. Med. Biol. 18, 337 (1976)

    Google Scholar 

  12. Picha, G., Helmus, M., Barenberg, S. et al: The characterization of intima development in left ventricular assist device and total artificial heart. Trans. Am. Soc. Artif. Intern. Organs 22, 554–568 (1976)

    PubMed  CAS  Google Scholar 

  13. Pierce, W. S., Landis, D., O’Bannon, W. et al.: Automatic control of the artificial heart. Trans. Am. Soc. Artif. Intern. Organs 22, 347–356 (1976)

    PubMed  CAS  Google Scholar 

  14. Rosenberg, G., Pierce, W. S., Brighton, J. A. et al.: A pressure measuring system for long term in vivo pressure measurements. Surgery 79, 456–459 (1976)

    PubMed  CAS  Google Scholar 

  15. Rushmer, R. F.: Cardiovascular dynamics, pp. 86. Philadelphia, London, Toronto: W. B. Saunders Co. 1970

    Google Scholar 

  16. Stanley, T. H., Kolff, W. J.: Effects of smooth vs. dacron-lined silastic artificial hearts on RBC restrictions, blood proteins and peripheral embolization. Surg. Forum 24, 171–173 (1973)

    PubMed  CAS  Google Scholar 

  17. Thumin, A., Reed, G., Lupo, F. et al.: A power transformer for mechanical hearts, Ch. 77. Hegyeli, R. J. (ed.), pp. 915–924. Artificial Heart Program Conference Proceedings. Washington, D. C.: United States Government Printing Office 1969

    Google Scholar 

Download references

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1979 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

Rosenberg, G., Landis, D.L., Donachy, J.H., Brighton, J.A., Stallsmith, J., Pierce, W.S. (1979). Design of the Pennsylvania State University Artificial Heart and Electronic Automatic Control System. In: Unger, F. (eds) Assisted Circulation. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-67268-2_36

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-67268-2_36

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-67270-5

  • Online ISBN: 978-3-642-67268-2

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics