Skip to main content

A Left Ventricular Aortic Blood Pump for Circulatory Support in Postoperative Patients With Acute Left Ventricular Failure

  • Chapter

Abstract

During the past decade investigations performed in this laboratory have resulted in the development of a series of axiosymmetric, double-valved blood pumps interposed between the left ventricular apex and thoracic aorta of calves [2, 10]. The devices were designed for potential use in two general groups of patients: first, those individuals undergoing a cardiac surgical operation who are unable to be weaned from cardiopulmonary bypass; and second, patients with extensive myocardial fibrosis and congestive heart failure who require chronic left ventricular support over a period of months or years. Recent progress in these studies (1975) resulted in approval by the National Heart, Lung, and Blood Institute, National Institutes of Health, of a Model X pump containing xenograft valves for use as a temporary clinical assist device [9]. A protocol for patient selection was also developed to ensure that only those few individuals who failed to respond to standard measures of cardiac resuscitation could become candidates for implantation of an assist device (LVAD).

This is a preview of subscription content, log in via an institution.

Buying options

Chapter
USD   29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD   84.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD   109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Learn about institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Angell, W. W., Buck, W., Shumway, N. E.: The viable homograft. In: Biologic, tissue in heart valve replacement. Ross, D.N., Wooler, G.H. (eds.). London: Butterworth & Co. Ltd. 1971.

    Google Scholar 

  2. Bernhard, W. F., LaFarge, C. G., Robinson, T., Yun, I., Shirahige, K.: An improved blood-pump interface for left ventricular bypass. Ann. Surg. 168, 750–764 (1968)

    Article  PubMed  CAS  Google Scholar 

  3. Bernhard, W. F., Husain, M., George, J., Curtis, G.: Fetal fibroblasts as a substratum for pseudoendothelial development on prosthetic surfaces. Surgery 66, 284–290 (1969 a)

    PubMed  CAS  Google Scholar 

  4. Bernhard, W. F., Husain, M., Robinson, T. C., Button, L., Frieze, S., Curtis, G. W.: An appraisal of blood trauma and the blood-material interface following prolonged assisted circulation. J. Thorac. Cardiovasc. Surg. 58, 801–810 (1969b)

    PubMed  CAS  Google Scholar 

  5. Bernhard, W. F., LaFarge, C. G., Jockin, H., Kitrilakis, S., Robinson, T.: Chronic left ventricular bypass with an implantable ventricularaortic assist pump. Circulation Suppl. I 39, 98, 1969 c

    Google Scholar 

  6. Bernhard, W. F., LaFarge, C. G., Jockin, H., Kitrilakis, S., Robinson, T.: Chronic left ventricular bypass with an implantable ventricularaortic assist pump. Circulation Suppl. I 40, 98, 1969 c

    Google Scholar 

  7. Bernhard, W. F., LaFarge, C. G., Husain, M., Yamamura, N., Robinson, T. C.: Physiological observations during partial and total left heart bypass. J. Thorac. Cardiovasc. Surg. 60, 807–817 (1970)

    PubMed  CAS  Google Scholar 

  8. Bernhard, W. F., Bankole, M. A., LaFarge, C. G., Bornhorst, W., Frieze, S., Curtis, G. W.: Development of an experimental model for functional cardiac replacement. Surgery 70, 205–213 (1971a)

    PubMed  CAS  Google Scholar 

  9. Bernhard, W. F., LaFarge, C. G., Bankole, M. A., Bornhorst, W.: Biventricular bypass: physiological studies during induced ventricular failure and fibrillation. J. Thorac. Cardiovasc. Surg. 62, 859–868 (1971b)

    PubMed  CAS  Google Scholar 

  10. Bernhard, W. F., Poirier, V., LaFarge, C. G., Carr, J.: A new method for temporary left ventricular bypass: preclinical appraisal. J. Thorac. Cardiovasc. Surg. 70, 880–895 (1975)

    PubMed  CAS  Google Scholar 

  11. Filler, R. M., Bernhard, W. F., Robinson, T., Bankole, M. A., LaFarge, C. G.: An implantable left ventricular-aortic assist device. J. Thorac. Cardiovasc. Surg. 54, 795–802 (1967)

    PubMed  CAS  Google Scholar 

  12. LaFarge, C. G., Bernhard, W. F., Robinson, T. C., Kitrilakis, S., Yun, I., Shirahige, K.: Physiological consequences of acutely and chronically implanted direct left ventricular-aortic assist devices. Trans. Am. Soc. Artif. Intern. Organs 14, 316–322 (1968)

    PubMed  CAS  Google Scholar 

  13. LaFarge, C. G., Husain, M., Ono, K., Robinson, T. C., Bernhard, W. F.: Biplane angiographic evaluation of chronically implanted left ventricular-aortic assist devices. Trans. Am. Soc. Artif. Intern. Organs 15, 454–459 (1969)

    CAS  Google Scholar 

  14. LaFarge, C. G., Carr, J. G., Coleman, S. J., Bernhard, W. F.: Hemodynamic studies during prolonged mechanical circulatory support. Trans. Am. Soc. Artif. Intern. Organs 18, 186–193 (1972 a)

    PubMed  CAS  Google Scholar 

  15. LaFarge, C. G., Carr, J. G., Coleman, S., Bernhard, W. F.: The maintenance of circulatory competence during chronic microsphere-induced myocardial failure. J. Thorac. Cardiovasc. Surg. 64, 652–658 (1972b)

    PubMed  CAS  Google Scholar 

  16. LaFarge, C. G., Poirier, V., Bornhorst, W., Bernhard, W. F.: An implantable power system for chronic left ventricular bypass. Trans. Am. Soc. Artif. Intern. Organs 23, 39 (1974)

    Google Scholar 

Download references

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1979 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

Bernhard, W.F., LaFarge, C.G., Carr, J.G., Keiser, J.T. (1979). A Left Ventricular Aortic Blood Pump for Circulatory Support in Postoperative Patients With Acute Left Ventricular Failure. In: Unger, F. (eds) Assisted Circulation. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-67268-2_16

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-67268-2_16

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-67270-5

  • Online ISBN: 978-3-642-67268-2

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics