Abstract
During the past decade investigations performed in this laboratory have resulted in the development of a series of axiosymmetric, double-valved blood pumps interposed between the left ventricular apex and thoracic aorta of calves [2, 10]. The devices were designed for potential use in two general groups of patients: first, those individuals undergoing a cardiac surgical operation who are unable to be weaned from cardiopulmonary bypass; and second, patients with extensive myocardial fibrosis and congestive heart failure who require chronic left ventricular support over a period of months or years. Recent progress in these studies (1975) resulted in approval by the National Heart, Lung, and Blood Institute, National Institutes of Health, of a Model X pump containing xenograft valves for use as a temporary clinical assist device [9]. A protocol for patient selection was also developed to ensure that only those few individuals who failed to respond to standard measures of cardiac resuscitation could become candidates for implantation of an assist device (LVAD).
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References
Angell, W. W., Buck, W., Shumway, N. E.: The viable homograft. In: Biologic, tissue in heart valve replacement. Ross, D.N., Wooler, G.H. (eds.). London: Butterworth & Co. Ltd. 1971.
Bernhard, W. F., LaFarge, C. G., Robinson, T., Yun, I., Shirahige, K.: An improved blood-pump interface for left ventricular bypass. Ann. Surg. 168, 750–764 (1968)
Bernhard, W. F., Husain, M., George, J., Curtis, G.: Fetal fibroblasts as a substratum for pseudoendothelial development on prosthetic surfaces. Surgery 66, 284–290 (1969 a)
Bernhard, W. F., Husain, M., Robinson, T. C., Button, L., Frieze, S., Curtis, G. W.: An appraisal of blood trauma and the blood-material interface following prolonged assisted circulation. J. Thorac. Cardiovasc. Surg. 58, 801–810 (1969b)
Bernhard, W. F., LaFarge, C. G., Jockin, H., Kitrilakis, S., Robinson, T.: Chronic left ventricular bypass with an implantable ventricularaortic assist pump. Circulation Suppl. I 39, 98, 1969 c
Bernhard, W. F., LaFarge, C. G., Jockin, H., Kitrilakis, S., Robinson, T.: Chronic left ventricular bypass with an implantable ventricularaortic assist pump. Circulation Suppl. I 40, 98, 1969 c
Bernhard, W. F., LaFarge, C. G., Husain, M., Yamamura, N., Robinson, T. C.: Physiological observations during partial and total left heart bypass. J. Thorac. Cardiovasc. Surg. 60, 807–817 (1970)
Bernhard, W. F., Bankole, M. A., LaFarge, C. G., Bornhorst, W., Frieze, S., Curtis, G. W.: Development of an experimental model for functional cardiac replacement. Surgery 70, 205–213 (1971a)
Bernhard, W. F., LaFarge, C. G., Bankole, M. A., Bornhorst, W.: Biventricular bypass: physiological studies during induced ventricular failure and fibrillation. J. Thorac. Cardiovasc. Surg. 62, 859–868 (1971b)
Bernhard, W. F., Poirier, V., LaFarge, C. G., Carr, J.: A new method for temporary left ventricular bypass: preclinical appraisal. J. Thorac. Cardiovasc. Surg. 70, 880–895 (1975)
Filler, R. M., Bernhard, W. F., Robinson, T., Bankole, M. A., LaFarge, C. G.: An implantable left ventricular-aortic assist device. J. Thorac. Cardiovasc. Surg. 54, 795–802 (1967)
LaFarge, C. G., Bernhard, W. F., Robinson, T. C., Kitrilakis, S., Yun, I., Shirahige, K.: Physiological consequences of acutely and chronically implanted direct left ventricular-aortic assist devices. Trans. Am. Soc. Artif. Intern. Organs 14, 316–322 (1968)
LaFarge, C. G., Husain, M., Ono, K., Robinson, T. C., Bernhard, W. F.: Biplane angiographic evaluation of chronically implanted left ventricular-aortic assist devices. Trans. Am. Soc. Artif. Intern. Organs 15, 454–459 (1969)
LaFarge, C. G., Carr, J. G., Coleman, S. J., Bernhard, W. F.: Hemodynamic studies during prolonged mechanical circulatory support. Trans. Am. Soc. Artif. Intern. Organs 18, 186–193 (1972 a)
LaFarge, C. G., Carr, J. G., Coleman, S., Bernhard, W. F.: The maintenance of circulatory competence during chronic microsphere-induced myocardial failure. J. Thorac. Cardiovasc. Surg. 64, 652–658 (1972b)
LaFarge, C. G., Poirier, V., Bornhorst, W., Bernhard, W. F.: An implantable power system for chronic left ventricular bypass. Trans. Am. Soc. Artif. Intern. Organs 23, 39 (1974)
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© 1979 Springer-Verlag Berlin Heidelberg
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Bernhard, W.F., LaFarge, C.G., Carr, J.G., Keiser, J.T. (1979). A Left Ventricular Aortic Blood Pump for Circulatory Support in Postoperative Patients With Acute Left Ventricular Failure. In: Unger, F. (eds) Assisted Circulation. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-67268-2_16
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DOI: https://doi.org/10.1007/978-3-642-67268-2_16
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