Zusammenfassung
Organspezifischer Substratfluß nach einer Mahlzeit
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Die Kohlenhydrate der Nahrung werden vor allem als Glucose, die Proteine als Aminosäuren und die Fette als Chylomikronen resorbiert. Ihren Energiebedarf decken praktisch alle Organe vorwiegend durch Abbau von Glucose; die Leber zusätzlich noch durch den Abbau von Aminosäuren. Die nicht zur direkten Energieproduktion benötigten resorbierten Substrate werden gespeichert. Energiespeicher bilden vor allem die Leber (Glykogen), die Muskeln (Glykogen und „Protein“) und das Fettgewebe (Triglycerid).
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Literatur
Organspezifischer Substratfluβ
Kuhnau, J.: Die heutige Ernährungssituation in der Wohlstandsgesellschaft. In: Ernährungswissenschaften (L. Heilmeyer, H. J. Holtmeier, Hrsg.), p. 100–111. Stuttgart: Thieme 1968.
Cahill, G. F., Owen, O. E.: Some Observations on Carbohydrate Metabolism in Man. In: Carbohydrate Metabolism and its Disorders (F. Dickens, P.J. Randle, W. J. Whelan, Eds.), Vol. 1, p. 497–522. New York: Academic Press 1968.
Krebs, H. A.: Some aspects of the regulation of fuel supply in omnivorous animals. Advanc. Enzyme Regulat. 10, 397–420 (1972).
Felig, P., Sherwin, R.: Carbohydrate Homeostasis, Liver and Diabetes. In: Progress in Liver Diseases (H. Popper, F. Schaffner, Eds.) vol. 5, p. 149–171. New York: Grune and Stratton 1976.
Hultman, E., Nilsson, L. H.: Liver glycogen in Man. Effect of Different Diets and Muscular Exercise. Adv. Exp. Med. Biol. 11, 143–151 (1971).
Stoff wechselsteuerung durch Insulin
Unger, R. H.: Alpha- and Beta-cell Interrelationships in Health and Disease. Metabolism 23, 581–593 (1974).
Cerasi, W.: Insulin secretion: mechanism of the stimulation by glucose. Quart. Rev. Biophys. 8, 1–41 (1975).
Renold, A. E., Stauffacher, W., Cahill, G. F.: Diabetes Mellitus. In: The Metabolic Basis of Inherited Disease (J. B. Stanbury, J. B. Wyngaarden, D. S. Fredrickson, Eds.), p. 83–118. New York: McGraw-Hill 1972.
Widdas, W. F.: Membrane Transport of Sugars. In: Carbohydrate Metabolism and its Disorders (F. Dickens, P. J. Randle, W. J. Whelan, Eds.), Vol. 1, p. 1–23. New York: Academic Press 1968.
Hepp, K. D.: Inhibition of Glucagon-stimulated Adenyl Cyclase by Insulin. FEBS Letters 12, 263 (1971).
Proceedings of the 50th Anniversary Insulin Symposium Diabetes 21 (Suppl. 2), 385–714 (1972).
Taunton, O. D., Stiefel, F. B., Greene, H. L., Herman, R. H.: Rapid Reciprocal Changes in Rat Hepatic Glycolytic Enzyme and Fructosediphosphatase Activities following Insulin and Glucagon Injection. J. biol. Chem. 249, 7228–7239 (1974).
Czech, M. P.: Molecular Basis of Insulin Action. Annu. Rev. Biochem. 46, 359–384 (1977).
Goldberg, N., Haddox, M. K.: cGMP metabolism and involvement in biological regulation. Annu. Rev. Biochem. 46, 823–896 (1977).
Manchester, K. L., Young, F. G.: The effect of insulin in vitro on the accumulation of amino acids by isolated rat diaphragm. Biochem. J. 75, 487–495 (1960).
Energiespeicherung
Hers, H. G., de Wulf, H., Stalmans, W., Van den Berghe, G.: The Control of Glycogen Synthesis in the Liver. Advanc. Enzyme Regulat. 8, 171–190 (1970).
Larner, J., Villar-Palasi, C.: Glycogen synthase and its control. Curr. Top. Cell. Regulat. 3, 196–236 (1971).
Larner, J.: Four Questions Times Two: A Dialogue on the Mechanism of Insulin Action Dedicated to Earl W. Sutherland. Metabolism 24, 249 (1975).
Lane, D. M., Moss, J., Polaris, S. E.: Acetyl Coenzyme A Carboxylase. Curr. Top. Cell. Regulat. 8, 139–195 (1974).
Vagelos, P. R.: Regulation of Fatty Acid Biosynthesis. Curr. Top. Cell. Regulat. 4, 119–166 (1971).
Numa, S., Yamashito, S.: Regulation of Lipogenesis in Animal Tissues. Curr. Top. Cell. Regulat. 8, 197–246 (1974).
Felts, J. M., Itakura, H., Crane, R. T.: The Mechanism of Assimilation of Chylomicrons, Very Low Density Lipoproteins and Remnants — A New Theory. Biochem. biophys. Res. Commun. 66, 1467–1475 (1975).
Whelan, W. J.: On the origin of primer for glycogen synthesis. Trends Biochem. Sci. 1, 13–15 (1976).
Baur, H., Heldt, H. W.: Transport of Hexoses across the Liver Cell Membrane. Europ. J. Biochem. 74, 397–403 (1977).
Lee, K. H., Kim, K. H.: Regulation of Rat Liver Acetyl-Coenzyme A Carboxylase. J. biol. Chem. 252, 1748–1751 (1977).
Jason, C. J., Polokoff, M. A., Bell, R. M.: Triacylglycerol Synthesis in Isolated Fat Cells. J. Biol. Chem. 251, 1488–1492 (1976).
Shimazu, T., Amakawa, A.: Regulation of glycogen metabolism in liver by the autonomic nervous system; possible mechanism of Phosphorylase activation by the splanchnic nerve. Biochim. biophys. Acta 385, 242–256 (1975).
Ekman, P., Dahlquist, U., Humble, E., Engström, L.: Comparative kinetic studies on the L-type pyruvate kinase from rat liver and the enzyme phosphorylated by cAMP-stimulated protein-kinase. Biochim. biophys. Acta 429, 374–382 (1976).
Energiegewinnung
Pontremoli, S., Grazi, E.: Hexose-Monophosphate Oxidation. In: Comprehensive Biochemistry (M. Florkin, E. H. Stotz, Eds.), Vol. 17, p. 163–189. New York: Elsevier 1969.
Mansour, T. E.: Phosphofructokinase. Curr. Top. Cell. Regulat. 5, 2–46 (1972).
Mansour, T. H.: Kinetic and Physical Properties of Phosphofructokinase. Advanc. Enzyme Regulat. 8, 37–52 (1970).
Ramaiah, A.: Pasteur Effect and Phosphofructokinase. Curr. Top. Cell. Regulat. 8, 298–345 (1974).
Seubert, W., Schoner, W.: The Regulation of Pyruvate Kinase. Curr. Top. Cell. Regulat. 3, 237–267 (1971).
Srere, P. A.: The Citrate Enzymes: Their Structures, Mechanisms and Biological Functions. Curr. Top. Cell. Regulat. 5, 229–283 (1972).
Krebs, H. A.: Rate Control of the Tricarboxylic Acid Cycle. Adv. Enzyme Regulat. 8, 335–353 (1970).
Newsholme, E. A., Start, C.: Regulation in metabolism, Chap. 3: Regulation of carbohydrate metabolism in muscle, p. 88–145. London: Wiley 1975.
Wurster, B., Hess, B.: Anomeric specificity of enzymes of D-glucose metabolism, FEBS Letters 40 Suppl., 112–118 (1974).
Brand, I., Müller, K., Unger, C., Söling, H.: In vivo and in vitro interconversions of active and inactive forms of phosphofructokinase in rat liver. FEBS Letters 68, 271–274 (1976).
Enzymopathische hämolytische Anämien
Valentine, W. N.: Deficiencies Associated With Embden-Meyerhof Pathway and Other Metabolic Pathways. Sem. Hematol. 8, 348–366 (1971).
Beutler, E.: Abnormalities of the Hexose Monophosphate Shunt. Sem. Hematol. 8, 311–347 (1971).
Arnold, H.: Zur Pathogenese, Differentialdiagnose und Therapie enzymopenischer hämolytischer Anämien. Therapiewoche, 26, 8783–92 (1976).
Galaktosämie
Segal, St.: Disorders of Galactose Metabolism. In: The Metabolic Basis of Inherited Diseases (J. B. Stanbury, J. B. Wyngaarden, D. S. Frederickson, Eds.), 3. Ed., p. 174–195. New York-London: McGraw-Hill 1972.
Sitzmann, F. C., Kaloud, H.: Angeborene Störung des Galactosestoffwechseis. Med. Klin. 70, 491–498 (1975).
Beutler, E., Srivastava, S.K.: GSH-Metabolism of the lens. In: Glutathione (L. Flohe, H. Ch. Benöhr, H. Sies, H. D. Waller, A. Wendel, Eds.), p. 201–205. Stuttgart: Thieme 1974.
Fructosurie und Fructoseintoleranz
Frosch, E. R.: Essential Fructosuria and Heriditary Fructoseintolerance. In: The Metabolic Bases of Inherited Diseases (J. B. Stanbury, J. B. Wyngaarden, D. S. Frederickson, Eds.), 3. Ed., p. 131–141. New York-London: McGraw-Hill 1972.
Gitzelmann, R., Baerlocher, B., Prader, A.: Heriditäre Störungen in Fructose- und Galactose-stoffwechsel. Mschr. Kinderheilk. 121, 174–180 (1973).
Hyperlipoproteinämien
Fredrickson, D. S., Levy, R. J., Lees, R. S.: Fat Transport in Lipoproteins — An Integrated Approach to Mechanisms and Disorders. New Engl. J. Med. 276, 13–44, 94–103, 148–156, 215–225, 273–281 (1967).
Greten, H.: Die primären Hyperlipoproteinämien. Münch. med. Wschr. 115, 639–643 (1973).
Levy, R. S.: Classification and Etiology of Hyperlipoproteinemias. Fed. Proc. 30, 829–834 (1971).
Schwandt, P.: Die sekundären Hyperlipoproteinämien. Münch. med. Wschr. 115, 644–649 (1973).
Undeutsch, D.: Fettstoffwechselstörungen. Stuttgart-New York: Schattauer 1975.
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Jungermann, K., Möhler, H. (1980). Bildung der Energiespeicher und Energiegewinnung in der Resorptionsphase. In: Biochemie. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-67258-3_5
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