Abstract
It is known that mechanical ventilation with continuous positive pressure ventilation (CPPV) increases PaO2 through VA/Q ratio improvement, by opening previously not ventilated but perfused areas and possibly favouring interstitial edema reabsorption (5, 9), though experimental studies tend to deny that effect (4). The improvement on gas exchange is clearly noted in different situations where alveolar instability and VA/Q imbalance play an outstanding role. This effect may be obscured when VA/Q inequalities or diffusion impairment are corrected breathing high oxygen mixtures. This is also less noticeable when hypoxemia is chiefly caused by intrapulmonary shunt due to cellular debris and fluid filled alveoli (12). Besides, several authors (9,11,17) have postulated that CPPV could, through a decrement in cardiac output, impair oxygen transport with the consequent tissue P02 decrement. This fact prompted us to study gas exchange and hemodynamics in a group of patients with bilateral bacterial bronchopneumonia mechanically ventilated with CPPV.
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Raimondi, G.A., Raimondi, A.C., Marchissio, M.L. (1979). Gas Exchange and Hemodynamic Effects of Continuous Positive Pressure Ventilation (CPPV) in Patients with Bacterial Bronchopneumonia. In: Tavares, B.M., Frey, R. (eds) Acute Care. Anaesthesiology and Intensive Care Medicine/Anaesthesiologie und Intensivmedizin, vol 116. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-67211-8_31
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DOI: https://doi.org/10.1007/978-3-642-67211-8_31
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