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The Influence of Colloidal Plasma Substitutes on Spontaneous and Induced Platelet Aggregation

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Abstract

Colloidal plasma substitutes, particularly dextrans, are increasingly used for thrombosis prophylaxis (1, 4, 5, 6, 8). Intra- and postoperatively they serve for volume substitution and for thrombosis prophylaxis as well. In internal medicine dextrans are used for prophylaxis of myocardial infarction, cerebral vascular accidents and thrombosis of arteriovenous shunts in patients on hemodialysis (7). The effect in thrombosis prophylaxis of dextran seems to be com-parable with that of oral anticoagulants.

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References

  1. Bergquist, E., Bergquist, D., Bronge, A., Dahlgren, S., Lindquist, B.: Effect of Dextrans on Platelet Adhesiveness and Aggregation.. Acta. Chir. Scand. 138, 689 (1971)

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  2. Breddin, K., Grun, H., Krzwanek, H.J., Schremmer, W.P.: On the Measurement of Spontaneous Platelet Aggregation. The Platelet Aggregation Test III. Thromb. Haemostas. 25, 669 (1976)

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  3. Bydgeman, S., Eliasso, A.: Effect of Dextran Infusion on the Adenosine Diphosphate Induced Adhesiveness and the Spreading Capacity of Human Blood Platelets. Thromb. Diath. Haemorrh. 15, 436 (1966)

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  4. Carter, A.E., Eban, R.: Suppressive Effect of Dextran on Platelet Adhesiveness. Br. J. Surg. 60, 681 (1973)

    Article  PubMed  CAS  Google Scholar 

  5. Evarts, C.M., Feil, E.J.: Effect of Dextrans in vitro on the Adenosine Diphosphate Induced Adhesiveness of Human Blood Platelets. J. Bone Joint Surg. (Br) 53, 1271 (1971)

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  6. Harris, W.H., Salzmann, E.W., de Sanctis, R.W., Coutts, R.D.: The effect of clinical dextran on platelet aggregation, adhesion, and ADP release in man: In vivo and in vitro studies. J. Am. Med. Ass. 220, 1319 (1972)

    CAS  Google Scholar 

  7. Köhler, H.: Prophylaxe und Therapie der Shuntthrombose bei terminaler Niereninsuffizienz. Klin. Wochenschr. 55, 49 (1977)

    Article  PubMed  Google Scholar 

  8. Lüders, K., Konold, P., Otten, G., Koslowski, L.: Postoperative Thrombolieprophylaxe. Randomisierte, prospektive Untersuchung zum Vergleich einer Thromboembolieprophylaxe mit Antikoagulantien (Heparin-Marcumar®) und Dextran 60 (Macrodex®). Chirurg. 12, 563 (1973)

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© 1979 Springer-Verlag Berlin Heidelberg

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Kirch, W., Kühler, H., von Gizycki, C. (1979). The Influence of Colloidal Plasma Substitutes on Spontaneous and Induced Platelet Aggregation. In: Tavares, B.M., Frey, R. (eds) Acute Care. Anaesthesiology and Intensive Care Medicine/Anaesthesiologie und Intensivmedizin, vol 116. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-67211-8_25

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  • DOI: https://doi.org/10.1007/978-3-642-67211-8_25

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-09210-0

  • Online ISBN: 978-3-642-67211-8

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