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C-Type Virus Expression in the Placenta

  • Conference paper
Book cover Perinatal Pathology

Part of the book series: Current Topics in Pathology ((CT PATHOLOGY,volume 66))

Abstract

During the last decade, interest in C-type RNA viruses has expanded with observations that virus may participate in normal host functions (i.e., embryogenesis, development, speciation) in addition to their role in the pathogenesis of some malignant and immune complex diseases. By the late 1960s, the correlation of C-type virus with leukemias and sarcomas in diverse animal species was well documented. Genetic breeding experiments provided evidence that, in some species (e.g., murine, avian), viral associated disease was apparently transmitted vertically whereas the epidemiology of leukemia in other species (e.g., feline, bovine) suggested horizontal spread (Tooze, 1973). The discovery in 1970 that all C-type viruses contain an RNA-directed DNA polymerase (i.e., reverse transcriptase) provided a molecular mechanism to explain the different patterns of C-type virus associated disease (Mitzutani and Temin, 1970;Baltimore, 1970).

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  1. Sandra Panem
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Editors and Affiliations

  1. Pathologisches Institut der Universität, Westring 17, D-4400, Münster/Westf., Germany

    E. Grundmann (Professor Dr.) (Professor Dr.)

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© 1979 Springer-Verlag Berlin Heidelberg

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Panem, S. (1979). C-Type Virus Expression in the Placenta. In: Grundmann, E. (eds) Perinatal Pathology. Current Topics in Pathology, vol 66. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-67205-7_6

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  • DOI: https://doi.org/10.1007/978-3-642-67205-7_6

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-67207-1

  • Online ISBN: 978-3-642-67205-7

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