Skip to main content

Second Tumors Complicating Cancer Chemotherapy

  • Conference paper

Part of the book series: Hämatologie und Bluttransfusion ((HAEMATOLOGY,volume 22))

Abstract

Cancer chemotherapy has achieved many great successes. Cytotoxic drug therapy can alone cure a significant number of patients with childhood leukemia, Hodgkins disease, diffuse histiocytic lymphoma, Burkitts tumor, choriocarcinoma in females and testicular carcinoma. Combined with surgery and/or radiation it has significantly improved the cure rates in pediatric tumors such as Wilms tumors, embryonal rhabdomyosarcoma, Ewing's sarcoma, retinoblastoma and osteogenic sarcoma. Currently one of the major investigative thrusts in clinical research is the use of drugs as adjuvant to surgery and/or radiation in adult solid tumors such as breast cancer, colo-rectal cancer, head and neck cancer and ovarian cancer.

This is a preview of subscription content, log in via an institution.

Buying options

Chapter
USD   29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD   54.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD   69.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Learn about institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Carter, S. K., and Soper, W. T.: The integration of chemotherapy into combined modality treatment of solid tumors. I. The Overall Strategy. Cancer Treatment Reviews 1, 1–13 (1974)

    Article  PubMed  CAS  Google Scholar 

  2. Sutow, W. W., Gehan, E. A., and Heyn, R. M. et al.: Comparison of survival curves 1956 versus 1962 in children with Wilms tumor and neuroblastoma. Pediatrics 45, 800–811 (1970)

    PubMed  CAS  Google Scholar 

  3. Farber, S.: Chemotherapy in the treatment of leukemia and Wilms tumor. JAMA 198, 826–836 (1966)

    Article  PubMed  CAS  Google Scholar 

  4. Carter, S. K., and Wasserman, T. H.: Interaction of experimental and clinical studies in combined modality treatment. Cancer Chemotherapy Report part 25, 235–241 (1975)

    Google Scholar 

  5. Schabel, F. M.: Concepts of systemic treatment of micro metastases. Cancer 35, 15–24 (1975)

    Article  PubMed  CAS  Google Scholar 

  6. Packard, R. A., Prosnitz, L. R. and Bobrow, S. N.: Selection of breast cancer patients for adjuvant chemotherapy. JAMA 238, 1034–1036 (1977)

    Article  Google Scholar 

  7. Carter, S. K.: Large bowel cancer — The current status of treatment. J. Natl. Cancer Institute 56, 3–10 (1976)

    CAS  Google Scholar 

  8. Fisher, B., Carbone, P., and Economou, S. et al.: L-Phenylalanine mustard (L-PAM) in the management of primary breast cancer — a report of early findings. New Engl. J. Med. 292, 117–122 (1975)

    Article  PubMed  CAS  Google Scholar 

  9. Fisher, B. and Redmund, C.: Studies of the national surgical adjuvant breast project. In: Adjuvant therapy of cancer. (Salmon, S. E. & Jones, S. E. eds.) Amsterdam—Oxford, New York: North Holland 1977

    Google Scholar 

  10. Bonadona, G., Rossi, A., Valagussa, P., Banfi, A., and Veronesi, D.: Adjuvant chemotherapy with CMF in breast cancer with positive axillary nodes in: Adjuvant therapy of cancer. (Salmon, S. E., & Jones, S. E. eds.) Amsterdam—Oxford, New York: North Holland 1977

    Google Scholar 

  11. Sieber, S. M., and Adamson, R. H.: Toxicity of antineoplastic agents in man. Chromosomal aberrations, effects, congenital malformations and carcinogenic potential. Adv. Cancer Res. 22, 57–155 (1975)

    Article  PubMed  CAS  Google Scholar 

  12. Rosner, F.: Acute leukemia as a delayed consequence of cancer chemotherapy. Cancer 37, 1033–1036 (1976)

    Article  PubMed  CAS  Google Scholar 

  13. Arseneau, J. C., Sponzo, R. W., Levin, D. L. et al.: Non-lymphomatous malignant tumors complicating Hodgkins disease: Possible association with intensive therapy. New Engl. J. Med. 287, 1119 (1972)

    Article  PubMed  CAS  Google Scholar 

  14. Canellos, G. P., Devita, V. T., Arseneau, J. C. et al.: Second malignancies complicating Hodgkins disease in remission. Lancet 1, 947–949 (1975)

    Article  PubMed  CAS  Google Scholar 

  15. Canellos, G. P.: Second malignancies complicating Hodgkins disease in remission. Lancet 1, 1294 (1975)

    Article  PubMed  CAS  Google Scholar 

  16. Coleman, C. N., Williams. C. J., Flint, A., Glatstein, E. J., Rosenberg, S. A., and Kaplan, H. A.: Hematologic neoplasia in patients treated for Hodgkins disease. N. Engl. J. Med. 297, 1249–1252 (1977)

    Article  PubMed  CAS  Google Scholar 

  17. Lerner, H.: Second malignancies diagnosed in breast cancer patients while receiving adjuvant chemotherapy at the Pennsylvania Hospital. Proc. Am. Assoc. Cancer Res. 18, 340 (1977)

    Google Scholar 

  18. Reimer, R. R., Hoover, R., Fraumeni, J. F., and Young, R. C.: Acute leukemia after alkylating-agent therapy of ovarian cancer. N. Engl. J. Med. 297, 177–181 (1977)

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1978 Springer-Verlag Berlin Heidelberg

About this paper

Cite this paper

Carter, S.K. (1978). Second Tumors Complicating Cancer Chemotherapy. In: Huber, H., Senn, H., Falkensammer, M. (eds) Adjuvante zytostatische Chemotherapie. Hämatologie und Bluttransfusion, vol 22. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-67111-1_4

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-67111-1_4

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-09069-4

  • Online ISBN: 978-3-642-67111-1

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics