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Inheritance and Expression of Chicken Genes That Are Related to Avian Leukosis Sarcoma Virus Genes

  • Chapter
Current Topics in Microbiology and Immunology

Part of the book series: Current Topics in Microbiology and Immunology ((CT MICROBIOLOGY,volume 83))

Abstract

Three different groups of avian C-type viruses have been shown to contain RNA-directed DNA polymerases (Table 1). Each of these groups has characteristic but unrelated RNA, structural proteins, and reverse transcriptase (Halpern et al., 1973; Mizutani and Temin, 1973; Kang and Temin, 1973; Moelling et al., 1975; Hanafusa, T. et al., 1976). The genetic information for these viruses is found in viral RNA as well as in cellular DNA. The current review focuses on the inheritance and expression of chicken genes that code for avian leukosis sarcoma virus (ALSVs) or viral products. These cellular genes will be referred to as endogenous viral genes. Viral genes that are carried in virus and introduced into cells by infection will be referred to as exogenous viral genes.

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References

  • Aaronson, S.A., Todaro, G.J., Scolnik, E.M.: Induction of murine c-type viruses from clonal lines of virus-free BALB/3T3 cells. Science 174, 157–159 (1971)

    Article  PubMed  CAS  Google Scholar 

  • Ando, T., Toyoshima, K.: Genetic control of chick helper factor in cells which lack natural group-specific antigen of avian leukosis. Virology 73, 521–527 (1976)

    Article  PubMed  CAS  Google Scholar 

  • Baluda, M.A.: Widespread presence, in chickens of DNA complementary to the RNA genome of avian leukosis viruses. Proc. Natl. Acad. Sci. U.S.A. 69, 576–580 (1972)

    Article  PubMed  CAS  Google Scholar 

  • Beard, J.W., Sharp, D.G., Eckert, E.A., Beard, D., Mommaerts, E.B.: Properties of the virus of the fowl erythromyeloblastic disease. Proc. Second Natl. Cancer Conf. 2, 1396–1411 (1952)

    Google Scholar 

  • Benveniste, R.E., Callahan, R., Sherr, C.J., Chapman, V., Todaro, G.J.: Two Distinct endoge-nous type C viruses isolated from the Asian rodent mus cervicolor: Conservation of virogene sequences in related rodent species. J. Virol. 27, 849–862 (1977)

    Google Scholar 

  • Biggs, P.M., Milne, B.S., Graf, T., Bauer, H.: Oncogenicity of non-transforming mutants of avian sarcoma viruses. J. Gen. Virol. 18, 399–403 (1973)

    Article  PubMed  CAS  Google Scholar 

  • Bister, K., Hayman, M.J., Vogt, P.K.: Defectiveness of avian myelocytomatosis virus Mc29: Isolation of long-term nonproducer cultures and analysis of virus-specific poly-peptide synthesis. Virology 82, 431–148 (1977)

    Article  PubMed  CAS  Google Scholar 

  • Boettiger, D., Love, D.N., Weiss, R.A.: Virus envelope markers in mammalian tropism of avian RNA tumor viruses. J. Virol. 15, 108–114 (1975)

    PubMed  CAS  Google Scholar 

  • Brodkorb, P.: Catalog of fossil birds, part 2 (Anseriformes through Galliformes). Bull. Florida State Mus. Biol. Ser. 8, 195–335 (1964)

    Google Scholar 

  • Brodkorb, P.: Origin and Evolution of Birds in Avian Biology. Farmer, D.S., King, J.R. (eds.) New York: Academic Press 1971, Vol. I, pp. 19–55

    Google Scholar 

  • Chen, J.H., Hanafusa, H.: Detection of a protein of avian leukoviruses in uninfected chick cells by radioimmunoassay. J. Virol. 13, 340–346 (1974)

    PubMed  CAS  Google Scholar 

  • Chen, J.H., Hayward, W.S., Hanafusa, H.: Avian tumor virus proteins and RNA in uninfected chicken embryo cells. J. Virol. 14, 1419–1429 (1974)

    PubMed  CAS  Google Scholar 

  • Chen, Y.C., Vogt, P.K.: Endogenous leukosis viruses in the avian family phasianidae. Virology 76, 740–750 (1977)

    PubMed  CAS  Google Scholar 

  • Coffin, J., Billeter, M.A.: A physical map of the Rous sarcoma virus genome. J. Mol. Biol. 100, 293–318 (1976)

    Article  PubMed  CAS  Google Scholar 

  • Coffin, J.M., Haseltine, W.A.: Terminal redundancy and the origina of replication of Rous sarcoma virus RNA. Proc. Natl. Acad. Sci. U.S.A. 74, 1908–1912 (1977)

    Article  PubMed  CAS  Google Scholar 

  • Coffin, J.M., Champion, M.A., Chabot, F.: Genome Structure of Avian RNA Tumor Viruses: Relationship Between Exogenous and Endogenous Viruses. The Proceedings of the ICREW-EMBO Workshop on Avian RNA Tumor Viruses. Barlati, S., DeGuili, C. (eds.) (in press) 1977

    Google Scholar 

  • Cook, M.K.: Cultivation of a filtrable agent associated with Marek’s disease. J. Nat’l. Cancer Inst. 43, 203–219 (1969)

    CAS  Google Scholar 

  • Cooper, G.M., Temin, H.M.: Lack of infectivity of the endogenous avian leukosis virus-related genes in the DNA of uninfected chicken cells. J. Virol. 17, 422–430 (1976)

    PubMed  CAS  Google Scholar 

  • Cooper, M.D., Payne, L.N., Dent, P.B.: Pathogenesis of avian lymphoid leukosis. I Histogenesis. J. Nat’l Cancer Inst. 41, 373–389 (1968)

    CAS  Google Scholar 

  • Cracraft, J.: Continental drift, Paleo-climatology, and evolution and biogeography of birds. J. Zool. (Lond.) 169, 455–545 (1973)

    Article  Google Scholar 

  • Crittenden, L.B., Motta, J. V.: The role of the tvb locus in genetic resistance to RSV(RAV-O). Virology 67, 327–334 (1975)

    Article  PubMed  CAS  Google Scholar 

  • Crittenden, L.B., Wendel, E.J., Motta, J.V.: Interaction of genes controlling resistance to RSV(RSV-O). Virology 52, 373–384 (1973)

    Article  PubMed  CAS  Google Scholar 

  • Crittenden, L.B., Smith, E.J., Weiss, R.A., Sarma, P.S.: Host gene control of endogenous avian leukosis virus production. Virology 57, 128–138 (1974)

    Article  PubMed  CAS  Google Scholar 

  • Crittenden, L.B., Motta, J. V, Smith, E.J.: Genetic control of RAV-0 production in chickens. Virology 76, 90–97 (1977)

    Article  PubMed  CAS  Google Scholar 

  • Delius, H., Duesberg, P.H., Mangel, W.F.: Electron microscope measurements of Rous sarcoma virus RNA. Cold Spring Harbor Symp. Quant. Biol. 39, 835–843 (1974)

    Google Scholar 

  • Dinowitz, M.: Inhibition of Rous sarcoma virus by α-amanitin: possible role of cell DNA- dependent RNA polymerase form II. Virology 66, 1–9 (1975)

    Article  PubMed  CAS  Google Scholar 

  • Dougherty, R.M., DiStefano, H.S.: Lack of relationship between infection with avian leukosis virus and the presence of COFAL antigen in chick embryos. Virology 29, 586–595 (1966)

    Article  PubMed  CAS  Google Scholar 

  • Duesberg, P.H., Vogt, P.K.: Gel electrophoresis of avian leukosis and sarcoma viral RNA in formamide: Comparison with other viral and cellular RNA species. J. Virol. 12, 594–599 (1973)

    PubMed  CAS  Google Scholar 

  • Duesberg, P.H., Robinson, H.L., Robinson, W.S., Huebner, R.J., Turner, H.C.: Proteins of Rous sarcoma virus. Virology 36, 73–86 (1968)

    Article  PubMed  CAS  Google Scholar 

  • Duesberg, P.H., Vogt, P.K, Bister, K, Troxler, D., Scolnick, E.M.: Oncogenic (one) Genes of Sarcoma, Leukemia and Carcinoma Viruses. The proceedings of the ICREW-EMBO Workshop on Avian RNA Tumor Viruses. Barlati, S., DeGuili, C. (eds.) (in press) 1977a

    Google Scholar 

  • Duesberg, P.H., Bister, K, Vogt, P.K.: The RNA of avian acute leukemia virus Mc29. Proc. Natl. Acad. Sci. U.S.A. 74, 4320–4324 (1977b)

    Article  CAS  Google Scholar 

  • Eisenman, R., Vogt, V.M.: The biosynthesis of oncovirus proteins. BBA Reviews on Cancer (submitted) (1977)

    Google Scholar 

  • Eisenman, R., Vogt, V.M., Diggelman, H.: Synthesis of avian RNA tumor virus structural proteins. Cold Spring Harbor Symp. Quant. Biol. 39, 1067–1075 (1975)

    PubMed  Google Scholar 

  • Eisenman, R., Shaikh, R., Mason, W.S.: Identification of an avian oncovirus polyprotein in uninfected chick cells. Cell 14, 89–104 (1978)

    Article  PubMed  CAS  Google Scholar 

  • Engelbreth-Holm, J., Rothe-Meyer, A.: Bericht über neue Erfahrungen mit einem Stamm Huhner-Erythroleukose. Acta Pathol. Microbiol. Scand. 9, 293–312 (1932)

    Article  Google Scholar 

  • Evans, R.M., Baluda, M.A., Shoyab, M.: Differences between the integration of avian myeloblastosis virus DNA in leukemic cells and of endogenous virus DNA in normal chicken cells. Proc. Natl. Acad. Sci. U.S.A. 71, 3152–3156 (1974)

    Article  PubMed  CAS  Google Scholar 

  • Fisher, J.M.M.: In the Fossil Record. Harland, W.B., Holland, C.H., House, M.R., Hughes, N.F., Reynolds, A.B., Rudwick, M.J.S., Satterthwaite, G.E., Tarlo, L.B.H., Willey, E.C. (eds.). London: Geological Society of London 1967, pp. 133–733

    Google Scholar 

  • Fleissner, E.: Chromatographic separation and antigenic analysis of proteins of the oncornaviruses. I. Avian leukemic sarcoma viruses. J. Virol. 8, 778–785 (1971)

    PubMed  CAS  Google Scholar 

  • Fujita, DJ., Chen, Y.C., Friis, R.R., Vogt, P.K.: RNA tumor viruses of pheasants: characterization of avian leukosis subgroup F and G. Virology 60, 558–571 (1974)

    Article  PubMed  CAS  Google Scholar 

  • Gage, L.P., Manning, R.F.: Determination of the multiplicity of the silk fibroin gene and detection of fibroin gene-related DNA in the genome of Bombyx mori. J. Mol. Biol. 101, 327–348 (1976)

    Article  PubMed  CAS  Google Scholar 

  • Graf, T.: Two types of target cells for transformation with avian myelocytomatosis virus. Virology 54, 398–413 (1973)

    Article  PubMed  CAS  Google Scholar 

  • Graf, T., Royer-Pohora, B., Schubert, G.E., Beug, H.: Evidence for the multiple oncogenic potential of cloned leukemia virus: in vitro and in vivo studies with avian erythroblastosis virus. Virology 71, 422–433 (1976)

    Article  Google Scholar 

  • Halpern, M.S., Friis, R.R.: The immunogenicity of the envelope glycoprotein of avian sarcoma virus. Proc. Natl. Acad. Sci. U.S.A. 75, 1962–1966 (1978)

    Article  PubMed  CAS  Google Scholar 

  • Halpern, M.S., Wade, E., Rucher, E., Baxter-Gabbard, K.L., Levine, A.S., Friis, R.R.: A study of the relationship of reticuloendotheliosis virus to the avian leukosis-sarcoma complex of viruses. Virology 53, 287–299 (1973)

    Article  PubMed  CAS  Google Scholar 

  • Halpern, M.S., Bolognesi, D.P., Friis, R.R., Mason, W.S.: Expression of the major viral glycoprotein of avian tumor virus in cells of chf(+) chicken embryos. J. Virol. 15, 1131–1140 (1975)

    PubMed  CAS  Google Scholar 

  • Hanafusa, H.: Analysis of the defectiveness of Rous sarcoma virus. III. Determining the influence of a new helper virus on the host range and susceptibility to interference of RSV. Virology 25, 248–255 (1965)

    Article  PubMed  CAS  Google Scholar 

  • Hanafusa, H., Hanafusa, T.: Further studies on RSV production from transformed cells. Virology 34, 630–636 (1968)

    Article  PubMed  CAS  Google Scholar 

  • Hanafusa, H., Hanafusa, T.: Noninfectious RSV deficient in DNA polymerase. Virology 43, 313–316 (1971)

    Article  PubMed  CAS  Google Scholar 

  • Hanafusa, H., Hanafusa, T., Rubin, H.: Analysis of the defectiveness of Rous sarcoma virus. II. Specification of Rous sarcoma virus antigenicity by helper virus. Proc. Natl. Acad. Sci. U.S.A. 51, 41–48 (1964)

    Article  PubMed  CAS  Google Scholar 

  • Hanafusa, H., Miyamoto, T., Hanafusa, T.: A cell-associated factor essential for formation of an infectious form of Rous sarcoma virus. Proc. Natl. Acad. Sci. U.S.A. 66, 314–321 (1970)

    Article  PubMed  CAS  Google Scholar 

  • Hanafusa, H., Hanafusa, T., Kawai, S., Lugenbühl, R.E.: Genetic control of expression of endogenous virus genes in chicken cells. Virology 58, 439–448 (1974a)

    Article  CAS  Google Scholar 

  • Hanafusa, H., Hayward, W.S., Chen, J.H., Hanafusa, T.: Control of expression of tumor virus genes in uninfected chicken cells. Cold Spring Harbor Symp. Quant. Biol. 39, 1139–1144 (1974b)

    Google Scholar 

  • Hanafusa, H., Halpern, C.C., Buchhagen, D.H., Kawai, S.: Recovery of avian sarcoma virus from tumors induced by transformation defective mutants. J. Exp. Med. 146, 1735–1747 (1977)

    Article  PubMed  CAS  Google Scholar 

  • Hanafusa, T., Hanafusa, H.: Isolation of leukosis-type virus from pheasant embryo cells: possible presence of viral genes in cells. Virology 51, 247–251 (1973)

    Article  PubMed  CAS  Google Scholar 

  • Hanafusa, T., Hanafusa, H., Miyamoto, T.: Recovery of a new virus from apparently normal chick cells by infection with avian tumor viruses. Proc. Natl. Acad. Sci. U.S.A. 67, 1797–1803 (1970)

    Article  PubMed  CAS  Google Scholar 

  • Hanafusa, T., Hanafusa, H., Miyamoto, T., Fleissner, E.: Existence and expression of tumor virus genes in chick embryo cells. Virology 47, 475–482 (1972)

    Article  PubMed  CAS  Google Scholar 

  • Hanafusa, T., Hanafusa, H., Metroka, C.E., Hayward, W.S., Rettenmier, C.W., Sawyer, R.C., Dougherty, R.M., DiStefano, H.S.: Pheasant viruses: a new class of ribodeoxyvi-ruses. Proc. Natl. Acad. Sci. U.S.A. 73, 1333–1337 (1976)

    Article  PubMed  CAS  Google Scholar 

  • Harrison, P.R., Birnie, G.D., Hell, A., Humphries, S., Young, B.D., Paul, J.: Kinetic studies of gene frequency. I. Use of a DNA copy of reticulocyte 9S RNA to estimate globin gene dosage in mouse tissues. J. Mol. Biol. 84, 539–554 (1974)

    Article  PubMed  CAS  Google Scholar 

  • Haseltine, W.A., Kleid, D.G., Panet, A., Rothenberg, E., Baltimore, D.: Ordered transcription of RNA tumor virus genomes. J. Mol. Biol. 106, 109–132 (1976)

    Article  PubMed  CAS  Google Scholar 

  • Haseltine, W.A., Maxam, A.M., Gilbert, W.: Rous sarcoma virus genome is terminally redundant: the 5′ sequence. Proc. Natl. Acad. Sci. U.S.A. 74, 989–993 (1977)

    Article  PubMed  CAS  Google Scholar 

  • Hayward, W.S.: Size and genetic content of viral RNAs in avian oncovirus infected cells. J. Virol. 24, 47–63 (1977)

    PubMed  CAS  Google Scholar 

  • Hayward, W.S., Hanafusa, H.: Detection of avian tumor virus RNA in uninfected chick embryo cells. J. Virol. 11, 157–167 (1973)

    PubMed  CAS  Google Scholar 

  • Hayward, W.S., Hanafusa, H.: Recombination between endogenous and exogenous RNA tumor virus genes as analyzed by nucleic acid hybridization. J. Virol. 75,1367–1377 (1975)

    Google Scholar 

  • Hayward, W.S., Hanafusa, H.: Independent regulation of endogenous and exogenous RNA tumor virus genes. Proc. Natl. Acad. Sci. U.S.A. 73, 2259–2263 (1976)

    Article  PubMed  CAS  Google Scholar 

  • Hu, S.S.F., Lai, M.M.C., Vogt, P.K.: Characterization of the env gene in avian oncoviruses by heteroduplex mapping. J. Virol, (in press)

    Google Scholar 

  • Huebner, R.J., Armstrong, D., Okuyan, M., Sarma, P.S., Turner, H.C.: Specific complement-fixing viral antigens in hamster and guinia pig tumors induced by the Schmidt-Ruppin strain of avian sarcoma. Proc. Natl. Acad. Sci. U.S.A. 51, 742–751 (1964)

    Article  PubMed  CAS  Google Scholar 

  • Humphries, S., Windass, T., Williamson, R.: Mouse globin gene expression in erythroid and non-erythroid tissues. Cell 7, 267–277 (1976)

    Article  PubMed  CAS  Google Scholar 

  • Ishizaki, R., Langlois, A.J., Chabot, J., Beard, J.W.: Component of strain Mc29 avian leukosis virus with the property of defectiveness. J. Virol. 8, 821–827 (1971)

    PubMed  CAS  Google Scholar 

  • Ivanov, X., Mladenov, Z., Nedyalkov, S., Todorov, T.G., Yakimov, M.: Experimental investigations into avian leucosis. V. Transmission, haematology and morphology of avian myelocytomatosis. Bull. Inst. Pathol. Comp. Anim Acad. Bulg. Sci. 10, 5–38 (1964)

    Google Scholar 

  • Jacquet, M., Groner, Y., Monroy, J., Hurwitz, J.: The in vitro synthesis of avian myeloblastosis RNA sequences. Proc. Natl. Acad. Sci. U.S.A. 71, 3045–3049 (1974)

    Article  PubMed  CAS  Google Scholar 

  • Joho, R.H., Billeter, M.A., Weissman, C.: Mapping of biological functions on RNA of avian tumor viruses: Location of regions required for transformation and determination of host range. Proc. Natl. Acad. Sci. U.S.A. 72, 4772–4776 (1975)

    Article  PubMed  CAS  Google Scholar 

  • Joho, R.H., Stoll, E., Friis, R.R., Billeter, M.A., Weissman, C.: A partial genetic map of Rous sarcoma virus RNA: Location of polymerase, envelope and transformation markers. In: Proc. ICN-UCLA Symp. Mol. Cell Biol. Baltimore, D., Huang, A., Fox, C.F. (eds.) N.Y.: Academic Press 1976, Vol. IV, pp. 127–145

    Google Scholar 

  • Jolles, J., Schoentgen, F., Jolles, P., Prager, E.M., Wilson, A.C.: Amino acid sequence and immunological properties of Chachalaca egg white lysozyme. J. Mol. Evol. 8, 59–78 (1976)

    Article  PubMed  CAS  Google Scholar 

  • Kang, C.Y., Temin, H.M.: Lack of sequence homology among RNAs of avian leukosis-sarcoma viruses, reticuloendotheliosis virus, and chicken endogenous RNA-directed DNA polymerase activity. J. Virol. 12, 1314–1324 (1973)

    PubMed  CAS  Google Scholar 

  • Kang, C.Y., Temin, H.M.: Reticuloendotheliosis virus nucleic acid sequences in cellular DNA. J. Virol. 14, 1179–1188 (1974)

    PubMed  CAS  Google Scholar 

  • Kawai, S., Hanafusa, H.: The effects of reciprocal changes in temperature on the transformed state of cells infected with a Rous sarcoma virus mutant. Virology 46, 470–479 (1971)

    Article  PubMed  CAS  Google Scholar 

  • Kawai, S., Hanafusa, H.: Genetic recombination with avian tumor virus. Virology 49, 37–44 (1972)

    Google Scholar 

  • Kawai, S., Duesberg, P H., Hanafusa, H.: Transformation-defective mutants of Rous sarcoma virus with src gene deletions of varying length. J. Virol. 24, 910–914 (1977)

    PubMed  CAS  Google Scholar 

  • Khoury, A.T., Hanafusa, H.: Synthesis and integration of viral DNA in chicken cells at different times after infection with various multiplicities of avian oncornavirus. J. Virol. 18, 383–400 (1976)

    Google Scholar 

  • Kung, H.J., Bailey, J.M., Davidson, N., Vogt, P.K., Nicolson, M.O., McAllister, R.M.: Electron microscope studies of RNA tumor virus RNA. Cold Spring Harbor Symp. Quant. Biol. 39, 827–834 (1974)

    Google Scholar 

  • Lai, M.M.C., Duesberg, P.H.: Adenylic acid-rich sequences in RNAs of Rous sarcoma virus and Rauscher mouse leukemia virus. Nature (Lond.) 235, 383–386 (1972)

    Article  CAS  Google Scholar 

  • Leamnson, R.N., Halpern, M.S.: Subunit structure of the glycoprotein complex of avian tumor virus. J. Virol. 18, 956–976 (1976)

    PubMed  CAS  Google Scholar 

  • Levin, J.G., Rosenak, M.J.: Synthesis of murine leukemia virus proteins associated with viruses assembled in actinomycin D-treated cells: Evidence for persistence of viral messenger RNA. Proc. Natl. Acad. Sci. U.S.A. 73, 1154–1158 (1976)

    Article  PubMed  CAS  Google Scholar 

  • Linial, M., Neiman, P.E.: Infection of chick cells by subgroup E virus. Virology 73, 508–520 (1976)

    Google Scholar 

  • Lowy, D.R., Rowe, W.P., Teich, N., Hartley, J.W.: Murine leukemia virus, high frequency activation in vitro by 5-Iododeoxyuridine and 5-bromodeoxyuridine. Science 174, 155–156 (1971)

    Google Scholar 

  • Ludford, C.G., Purchase, H.G., Cox, H.W.: Duck infectious anemia virus associated with Plasmodium lophurae. Exp. Parasitol. 31, 29–38 (1972)

    Article  PubMed  CAS  Google Scholar 

  • Martin, G.S.: Rous sarcoma virus: a function required for maintenance of the transformed state. Nature (Lond.) 227, 1021–1023 (1970)

    Article  PubMed  CAS  Google Scholar 

  • Mizutani, S., Temin, H.M.: Lack of serological relationship among DNA polymerases of avian leukosis-sarcoma virus, reticuloendotheliosis viruses and chicken cells. J. Virol. 72, 440–448 (1973)

    Google Scholar 

  • Moelling, K., Gelderblom, H., Pauli, G., Friis, R., Bauer, H.: A comparitive study of the avian reticuloendotheliosis virus: Relationship to murine leukemia virus and viruses of the avian sarcoma-leukosis complex. Virology 65, 546–557 (1975)

    Article  PubMed  CAS  Google Scholar 

  • Moscovici, C.: Leukemic transformation with avian myeloblastosis virus: Present status. In: Current Topics of Microbiology and Immunology. Berlin-Heidelberg-New York: Springer 1975, pp. 79–101

    Google Scholar 

  • Moscovici, C., Alexander, R.W., Moscovici, M.G., Vogt, P.K.: Transforming and Oncogenic Effects of MH-2 Virus. The Proc. of the ICREW-EMBO Workshop on Avian RNA Tumor Viruses. Barlati, S., DeGiuli, C. (eds.) (in press) 1977

    Google Scholar 

  • Motta, J.V., Crittenden, L.B., Purchase, H.G., Stone, H.A., Okazaki, W., Witter, R.L.: Low oncogenic potential of avian endogenous RNA tumor virus infection or expression. J. Natl. Cane. Inst. 55, 685–689 (1975)

    CAS  Google Scholar 

  • Murray, J.A., Begg, A.M.: Histology and histogenesis of a filtrable endothelioma of the fowl. Sci. Rep. Cancer Research Fd. (Lond.) 9, 1–13 (1930)

    Google Scholar 

  • Neiman, P.E.: Measurement of endogenous leukosis virus nucleotide sequences in the DNA of normal avian embryos by RNA-DNA hybridization. Virology 53, 196–204 (1973)

    Google Scholar 

  • Neiman, P.E., Wright, S.E., McMillan, C., MacDonnell, D.: Nucleotide sequence relationships of avian RNA tumor virus: Measurement of the deletion in a transformation-defective mutant of Rous sarcoma virus. J. Virol. 13, 837–846 (1974a)

    CAS  Google Scholar 

  • Neiman, P.E., Wright, S.E., Purchase, H.G.: Studies of the interrelationship of chicken leukosis virus and host cell genomes by RNA-DNA hybridization. Cold Spring Harbor Symp. Quant. Biol. 39, 875–883 (1974b)

    Google Scholar 

  • Neiman, P.E., Das, S., MacDonnell, D., McMillin-Helsel, C.: Organization of shared and unshared sequences in the genomes of chicken endogenous and sarcoma viruses. Cell 11, 321–329 (1977)

    Google Scholar 

  • Nolan, R.A., Brush, A.H., Arnheim, N., Wilson, A.C.: An inconsistency between protein resemblance and toxenemic resemblance: Immunological comparison of diverse proteins from Gallinaceous birds. The Condor 77, 154–159 (1975)

    Article  Google Scholar 

  • Opperman, H., Bishop, J.M., Varmus, H.E., Levintow, L.: A joint product of the genes gag and pol of avian sarcoma virus: A possible precursor of reverse transcriptase. Cell 12, 993–1005 (1977)

    Article  Google Scholar 

  • Padgett, T.G., Stubblefield, E., Varmus, H.E.: Chicken macrochromosomes contain an endogenous provirus and microchromosomes contain sequences related to the transforming gene of ASV. Cell 10, 649–657 (1977)

    Google Scholar 

  • Pani, P.K.: Studies in genetic resistance to RSV(RAV-O) a third type of genetic resistance typified by the W line of fowl and further support for the two loci genetic model. J. Gen. Virol. 23, 33–40 (1974)

    Article  PubMed  CAS  Google Scholar 

  • Pani, P.K., Payne, L.N.: Further evidence for two loci which control susceptibility of fowl to RSV (RAV-0). J. Gen. Virol. 79, 235–244 (1973)

    Article  Google Scholar 

  • Parsons, J.T., Coffin, J.M., Haroz, R.K., Bromley, P.A., Weissman, C.: Quantitative determination and location of newly synthesized virus-specific ribonucleic acid in chicken cells infected with Rous sarcoma virus. J. Virol. 77, 761–774 (1973)

    Google Scholar 

  • Paskind, M.P., Weinberg, R.A., Baltimore, D.: Dependence on Moloney murine leukemia virus production on cell growth. Virology 67, 242–248 (1975)

    Article  PubMed  CAS  Google Scholar 

  • Payne, L.N., Chubb, R.: Studies on the nature and genetic control of an antigen in normal chick embryos which react in the CoFAL text. J. Gen. Virol. 3, 379–391 (1968)

    Article  PubMed  CAS  Google Scholar 

  • Payne, L.N., Pani, P.K., Weiss, R.A.: A dominant epistatic gene which inhibits susceptibility to RSV(RAV-O). J. Gen. Virol. 13, 455–62 (1971)

    Article  PubMed  CAS  Google Scholar 

  • Pease, M.: Inbreeding in poultry live stock improvement. Offic. Rept. 8th World’s Poultry Congr. 7, 33–42 (1948)

    Google Scholar 

  • Pease, M., Dudley, F.: Hybrid vigour in poultry. Rept. Proc. 10th World’s poultry Congr. 2, 45–49 (1954)

    Google Scholar 

  • Peterson, R.D., Burmeister, B.R., Fredrickson, T.N.: Effect of bursectomy and thymectomy on the development of visceral lymphomatosis in the chicken. J. N. C. I. 32, 1343–1354 (1964)

    Google Scholar 

  • Prager, E.M., Wilson, A.C.: Congruency of phylogenes derived from different proteins. J. Mol. Evol. 9, 45–57 (1976)

    Article  PubMed  CAS  Google Scholar 

  • Prager, E.M., Arnheim, N., Mross, G.A., Wilson, A.C.: Amino acid sequence studies on Bobwhite Quail egg white lysozyme. J. Biol. Chem. 247, 2905–2916 (1972)

    PubMed  CAS  Google Scholar 

  • Prager, E.M., Brush, A.H., Nolan, R.A., Nakanishi, M., Wilson, A.C.: Slow evolution of transferrin and albumin in birds according to microcomplement fixation analysis. J. Mol. Evol. 3, 243–262 (1974)

    Article  PubMed  CAS  Google Scholar 

  • Purchase, H.G., Burmeister, B.R.: Leukosis/sarcoma group. In: Diseases of Poultry, 7th ed. Hofstad, M.S., Calnek, B.W., Helmboldt, C.F., Reid, W.M., Yoder, H.W., Jr. (eds.) The Iowa State Univ. Press, Ames. 1977, pp. 418–468

    Google Scholar 

  • Purchase, H.G., Gilmour, D.S.: Lymphoid leukosis in chickens chemically bursectomized and subsequently inoculated with Bursa cells. J. Nat. Cane. Inst. 55, 851–855 (1975)

    CAS  Google Scholar 

  • Purchase, H.G., Ludford, C., Nazerian, K., Cox, H.W.: A new group of oncogenic virus: reticuloendotheliosis, chick syncitial, duck infectious anemia, and spleen necrosis viruses. J. Natl. Cane. Inst. 51, 489–499 (1973)

    CAS  Google Scholar 

  • Purchase, H.G., Okazaki, W., Vogt, P.K., Hanafusa, H., Burmeister, B.R., Crittenden, L.B.: Oncogenicity of avian leukosis viruses of different subgroups and of mutants of sarcoma viruses. Infect. Immun. 15, 423–428 (1977a)

    CAS  Google Scholar 

  • Purchase, H.G., Gilmour, D.G., Romero, C.H., Okazaki, W.: Post-infection genetic resistance to avian lymphoid leukosis resides in B target cells. Nature (Lond.) 270, 61–62 (1977b)

    Article  CAS  Google Scholar 

  • Rettenmeir, C.W., Hanafusa, H.: Structural protein markers in the avian oncoviruses. J. Virol. 24, 850–864 (1977)

    Google Scholar 

  • Robinson, H.L.: Isolation of noninfectious particles containing Rous sarcoma virus RNA from the medium of Rous sarcoma virus-transformed nonproducer cells. Proc. Natl. Acad. Sci. U.S.A. 57, 1655–1662 (1967)

    Article  PubMed  CAS  Google Scholar 

  • Robinson, H.L.: Intracellular restriction on the growth of induced subgroup E avian type C virus in chicken cells. J. Virol. 18, 856–866 (1976)

    PubMed  CAS  Google Scholar 

  • Robinson, H.L., Lamoreux, W.F.: Expression of endogenous ALV antigens and susceptibility to subgroup E ALV in three strains of chickens. Virology 69, 50–62 (1976)

    Article  PubMed  CAS  Google Scholar 

  • Robinson, H.L., Swanson, C.A., Hruska, J.F., Crittenden, L.B.: The production of unique C type viruses by chicken cells grown in Bromodeoxyuridine. Virology 69, 63–74 (1976)

    Article  PubMed  CAS  Google Scholar 

  • RohrSchneider, L., Bauer, H., Bolognesi, D.P.: Group-specific antigenic determinants of the large envelope glycoprotein of avian oncornaviruses. Virology 67, 234–241 (1975)

    Article  Google Scholar 

  • Rosenthal, P.N., Robinson, H.L., Robinson, W.S., Hanafusa, T., Hanafusa, H.: DNA in uninfected and virus-infected cells complementary to avian tumor virus RNA. Proc. Natl. Acad. Sci. U.S.A. 68, 2336–2340 (1971)

    Google Scholar 

  • Rous, P.: A sarcoma of the fowl transmissible by an agent separable from the tumor cells. J. Exp. Med. 13, 397–411 (1911)

    Article  PubMed  CAS  Google Scholar 

  • Rubin, H., Vogt, P.K.: An avian leukosis virus associated with stocks of Rous sarcoma virus. Virology 77, 184–194 (1962)

    Article  Google Scholar 

  • Rymo, L., Parsons, J.T., Coffin, J.M., Weissmann, C.: In vitro synthesis of Rous sarcoma virus specific RNA is catalyzed by a DNA-dependent RNA polymerase. Proc. Natl. Acad. Sci. U.S.A. 77, 2782–2786 (1974)

    Article  Google Scholar 

  • Sawyer, R.C., Hanafusa, H.: Formation of reticuloendotheliosis virus pseudotypes of Rous sarcoma virus. J. Virol. 22, 634–639 (1977)

    PubMed  CAS  Google Scholar 

  • Scheele, C.M., Hanafusa, H.: Proteins of helper-dependent RSV. Virology 45, 401–410 (1971)

    Google Scholar 

  • Schincariol, A.L., Joklik, W.K.: Early synthesis of virus-specific RNA and DNA in cells rapidly transformed with Rous sarcoma virus. Virology 56, 532–548 (1973)

    Article  PubMed  CAS  Google Scholar 

  • Schwartz, D.E., Zamecnik, P.C., Weith, H.C.: Rous sarcoma virus genome is terminally redundant: the 3′ sequence. Proc. Natl. Acad. Sci. U.S.A. 74, 994–998 (1977)

    Article  PubMed  CAS  Google Scholar 

  • Sevoian, M., Larose, R.N., Chamberlain, D.M.: Avian lymphomatosis VI. A virus of unusual potency and pathogenicity. Avian Dis. 7, 336–347 (1964)

    Article  Google Scholar 

  • Shine, J., Czernilofsky, A.P., Friedrick, R., Bishop, J.M., Goodman, H.M.: Nucleotide sequence at the 5′ terminus of the avian sarcoma virus genome. Proc. Natl. Acad. Sci. U.S.A. 74, 1473–1477 (1977)

    Article  PubMed  CAS  Google Scholar 

  • Shoyab, M., Baluda, M.A.: Homology between avian oncornavirus RNAs and DNA from several avian species. J. Virol. 16, 1492–1502 (1975)

    PubMed  CAS  Google Scholar 

  • Shoyab, M., Baluda, M.A.: Ribonucleotide sequence homology among avian oncornaviruses. J. Virol. 77, 106–113 (1976)

    Google Scholar 

  • Smith, E.J., Crittenden, L.B., Brinsfield, T.H., Jr.: Status of the endogenous avian leucosis virus in resistant cells from a producing line. Virology 61, 594–596 (1974)

    Article  PubMed  CAS  Google Scholar 

  • Smith, E.J., Stephenson, J.R., Crittenden, L.B., Aarronson, J.A.: Avian Leukosis-sarcoma virus gene expression. Non-coordinate control of group-specific antigens in virus-negative avian cells. Virology 70, 493–501 (1976)

    Article  PubMed  CAS  Google Scholar 

  • Smith, E.J., Crittenden, LB., Whitson, A.K.: Radioimmunoassay for the envelope glycoprotein of subgroup E avian leukosis-sarcoma viruses. Virology 84, 331–340 (1978)

    Article  PubMed  CAS  Google Scholar 

  • Somes, R.G., Jr.: Registry of Poultry Genetic Stocks in North America. A Directory of Specialized Lines and Strains, Mutations, Breeds, and Varieties of Chickens, Japanese Quail and Turkeys. Univ. of Connecticut, Storrs, 06268: Storrs Agricultural Experimental Station 1974

    Google Scholar 

  • Somes, R.G., Jr.: Symposium on Nomenclature and Gene Symbolism. 66th Annual Meeting, Poultry Science Association, Auburn, Alabama, August 8–12, 1977

    Google Scholar 

  • Staats, J.: Nomenclature in Biology of the Laboratory Mouse, 2nd ed. Green, E.L. (ed.) N.Y.-Toronto-Sydney-London: The Blakiston Div., McGraw-Hill Book 1966, pp. 45–50

    Google Scholar 

  • Stacey, D. W., Allfrey, V.G., Hanafusa, H.: Microinjection analysis of envelope-glycoprotein messenger activities of avian leukosis viral RNAs. Proc. Natl. Acad. Sci. U.S.A. 74, 1614–1618 (1977)

    Google Scholar 

  • Stehelin, D., Graf, T.: Avian myelocytomatosis virus and erythroblastosis virus lack the transforming gene src of avian sarcoma virus. Cell (submitted)

    Google Scholar 

  • Stehelin, D., Guntaka, R.V., Varmus, H.C., Bishop, J.M.: Purification of DNA complementary to nucleotide sequences required for neoplastic transformation of fibroblasts by avian sarcoma virus. J. Mol. Biol. 101, 346–365 (1976a)

    Article  Google Scholar 

  • Stehelin, D., Varmus, H.E., Bishop, J.M., Vogt, P.K.: DNA related to the transforming gene(s) of avian sarcoma viruses is present in normal avian DNA. Nature (Lond.) 260, 170–173 (1976b)

    Article  CAS  Google Scholar 

  • Stehelin, D., Roussel, M., Gardes, M.: The Transforming Gene of Avian Sarcoma Viruses. The Proc. of the ICREW-EMBO Workshop on Avian RNA Tumor Virus. Barlati, S., DeGiuli, C. (eds.) (in press) 1977

    Google Scholar 

  • Stephenson, J.R., Wilsnack, R.E., Aaronson, S.A.: Radioimmunoassay for avian C-type virus group specific antigen: Detection in normal and virus transformed cells. J. Virol. 77, 893–899 (1973)

    Google Scholar 

  • Stone, H.A.: Use of highly inbred chickens in research. U.S. Dept. Agricult. Tech. Bull. #1514, 1–22 (1975)

    Google Scholar 

  • Suzuki, Y., Brown, D.D.: Isolation and identification of the messenger RNA for silk fibroin from Bombyx mori. J. Mol. Biol. 63, 409–429 (1972)

    Article  PubMed  CAS  Google Scholar 

  • Tal, J., Kung, H-S., Varmus, H.E., Bishop, J.M.: Characterization of DNA complementary to nucleotide sequences adjacent to poly (A) at the 3′-terminus of the avian sarcoma virus genome. Virology 79, 183–197 (1977)

    Article  PubMed  CAS  Google Scholar 

  • Temin, Ü.M., Kassner, V.K.: Avian leukosis viruses of different subgroups and types isolated after passage of Rous sarcoma virus-Rous associated virus-0 in cells from different Ring Neck Pheasant embryos. J. Virol. 19, 302–312 (1976)

    PubMed  CAS  Google Scholar 

  • Tereba, A., Skoog, L., Vogt, P.K.: RNA tumor virus specific sequences in nuclear DNA of several avian species. Virology 65, 524–534 (1975)

    Article  PubMed  CAS  Google Scholar 

  • Theilen, G.H., Zeigel, R.F., Tweihaus, M.J.: Biological studies with RE virus (strain T) that induces reticuloendotheliosis in turkeys, chickens and Japanese quail. J. Natl. Cane. Inst. 37, 731–743 (1966)

    CAS  Google Scholar 

  • Todaro, G.J.: Five distinct genetically transmitted retrovirus groups in primates. J. Supramolecular Structure. Supplement 2, p. 225 (1978)

    Google Scholar 

  • Toyoshima, K, Vogt, P.K.: Temperature sensitive mutants of an avian sarcoma virus. Virology 39, 930–931 (1969)

    Article  PubMed  CAS  Google Scholar 

  • Trager, W.: A new virus of chicks interfering with development of malaria parasite (Plasmodium lophurae). Proc. Soc. Exp. Biol. Med. 101, 578–582 (1959)

    PubMed  CAS  Google Scholar 

  • Varmus, H.E., Weiss, R.A., Friis, R.R., Levinson, W., Bishop, J.M.: Detection of avian tumor virus-specific nucleotide sequences in avian cell DNAs. Proc. Natl. Acad. Sci. U.S.A. 69, 20–24 (1972)

    Article  PubMed  CAS  Google Scholar 

  • Varmus, U.E., Heasley, S., Bishop, J.M.: Use of DNA-DNA annealing to detect new virus-specific DNA sequences in chicken embryo fibroblasts after infection by avian sarcoma virus. J. Virol. 14, 895–903 (1974)

    PubMed  CAS  Google Scholar 

  • Vogt, P.K.: Phenotypic mixing in the avian tumor virus group. Virology 32, 708–717 (1967a)

    Article  CAS  Google Scholar 

  • Vogt, P.K: A virus released by “non producing” Rous sarcoma cells. Proc. Natl. Acad. Sci. U.S.A. 58, 801–808 (1967b)

    Article  CAS  Google Scholar 

  • Vogt, P.K.: Envelope classification of avian RNA tumor viruses. In: Comparative Leukemia Research. Bibl. Haemat. 36 (1969) Dutcher, R.M. (ed.) Basel-München-Paris-N.Y.: Karger 1970, pp. 153–167

    Google Scholar 

  • Vogt, P.K.: Spontaneous segregation of non-transforming viruses from cloned sarcoma viruses. Virology 46, 939–946 (1971)

    Article  PubMed  CAS  Google Scholar 

  • Vogt, P.K, Friis, R.R.: An avian leukosis virus related to RSV(0): Properties and evidence for helper activity. Virology 34, 223–234 (1971)

    Article  Google Scholar 

  • Vogt, P.K., Hu, S.S.F.: The genetic structure of RNA tumor viruses. Ann. Rev. Genet. 11, 203–208 (1977)

    Google Scholar 

  • Vogt, P.K, Ishizaki, R.: Reciprocal patterns of genetic resistance to avian tumor virus in two lines of chickens. Virology 26, 664–612 (1965)

    Article  PubMed  CAS  Google Scholar 

  • Vogt, P.K, Ishizaki, R.: Patterns of viral interference in the avian leukosis and sarcoma complex. Virology 30, 368–374 (1966)

    Article  PubMed  CAS  Google Scholar 

  • Vogt, P.K, Spencer, J.L., Okazaki, W., Witter, R.L., Crittenden, L.B.: Phenotypic mixing between reticuloendotheliosis virus and avian sarcoma viruses. Virology 80, 127–135 (1977)

    Google Scholar 

  • Vogt, V.M., Eisenman, R.: Identification of a large polypeptide precursor to avian oncornavirus proteins. Proc. Natl. Acad. Sci. U.S.A. 70, 1734–1738 (1973)

    Article  PubMed  CAS  Google Scholar 

  • Vogt, V.M., Eisenman, R., Diggelman, H.: Generation of avian myeloblastosis virus structural proteins by proteolytic cleavage of a precursor polypeptide. J. Mol. Biol. 96, 471–494 (1975)

    Google Scholar 

  • Wang, L.H., Duesberg, P.E., Beeman, K, Vogt, P.K.: Mapping RNAse Trresistant oligo-nucleotides of avian tumor virus RNAs: Sarcoma-specific oligonucleotides are near the poly(A) end and oligonucleotides common to sarcoma and transformation-defective viruses are at the Poly(A) end. J. Virol. 16, 1051–1070 (1975)

    PubMed  CAS  Google Scholar 

  • Wang, L.H., Duesberg, P.H., Kawai, S., Hanafusa, H.: Location of envelope-specific and sarcoma-specific oligonucleotides on RNA of Schmidt-Ruppin Rous sarcoma virus. Proc. Natl. Acad. Sci. U.S.A. 73, 447–451 (1976a)

    Article  CAS  Google Scholar 

  • Wang, L.H., Galehouse, D., Mellon, P., Duesberg, P., Mason, W.S., Vogt, P.K.: Mapping oligonucleotides of Rous sarcoma virus RNA that segregate with polymerase and group specific antigen markers in recombinants. Proc. Natl. Acad. Sci. U.S.A. 73, 3952–3956 (1976b)

    Article  CAS  Google Scholar 

  • Wang, S.V., Hayward, W.S., Hanafusa, H.: Genetic variation in the RNA transcripts of endogenous virus genes in uninfected chicken cells. J. Virol. 24, 64–73 (1977)

    PubMed  CAS  Google Scholar 

  • Weiss, R.A.: Spontaneous virus production from non-virus producing Rous sarcoma cells. Virology 32, 719–722 (1967)

    Article  PubMed  CAS  Google Scholar 

  • Weiss, R.A.: The host range of Bryan strain Rous sarcoma virus synthesized in the absence of helper virus. J. Gen. Virol. 5, 511–528 (1969a)

    Article  Google Scholar 

  • Weiss, R.A.: Interference and neutralization studies with Bryan strain Rous sarcoma virus synthesized in the absence of helper virus. J. Gen. Virol. 5, 529–539 (1969b)

    Article  Google Scholar 

  • Weiss, R.A., Biggs, P.M.: Leukosis and Marek’s disease viruses of feral red jungle fowl and domestic fowl in Malaya. J. Natl. Cane. Inst. 49, 1713–1725 (1972)

    CAS  Google Scholar 

  • Weiss, R.A., Payne, L.N.: The heritable nature of the factor in chicken cells which acts as a helper virus for Rous sarcoma virus. Virology 45, 508–515 (1971)

    Article  PubMed  CAS  Google Scholar 

  • Weiss, R.A., Friis, R.R., Katz, E., Vogt, P.K.: Induction of avian tumor viruses in normal cells by physical and chemical carcinogens. Virology 46, 920–938 (1971)

    Article  PubMed  CAS  Google Scholar 

  • Weiss, R.A., Mason, W.S., Vogt, P.K.: Genetic recombinants and heterozygotes derived from endogenous and exogenous avian RNA tumor viruses. Virology 52, 535–552 (1973)

    Article  PubMed  CAS  Google Scholar 

  • Weiss, R.A.: Helper Viruses and Helper Cells in RNA Viruses and Host Genome in Oncogenesis. Emmelot, P., Bentzvelzen, P. (eds.) Amsterdam: North Holland

    Google Scholar 

  • Weiss, S.R., Varmus, H.E., Bishop, J.M.: The size and genetic composition of virus specific RNAs in the cytoplasm of cells producing avian sarcoma leukosis viruses. Cell 12, 983–992 (1977)

    Article  PubMed  CAS  Google Scholar 

  • Weissbach, A., Bolden, A., Muller, R., Hanafusa, H., Hanafusa, T.: Deoxyribonucleic Acid polymerase activities in normal and leukovirus infected chicken embryo cells. J. Virol. 10, 321–327 (1972)

    PubMed  CAS  Google Scholar 

  • Wetmore, A.: A classification for the birds of the world. Smithsonian Misc. Coll. 139, 1–37 (1960)

    Google Scholar 

  • Witter, R.L., Purchase, H.G., Burgoyne, G.H.: Peripheral nerve lesions similar to those of Marek’s disease in chickens inoculated with reticuloendotheliosis virus. J. Natl. Cane. Inst. 45, 567–577 (1970)

    CAS  Google Scholar 

  • Wright, S.E., Neiman, P.K.: Base-sequence relationships between avian ribonucleic acid endogenous and sarcoma viruses assayed by competitive ribonucleic acid-deoxyribonucleic acid hybridization. Biochemistry 13, 1549–1554 (1974)

    Article  PubMed  CAS  Google Scholar 

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    Harriet L. Robinson

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Robinson, H.L. (1978). Inheritance and Expression of Chicken Genes That Are Related to Avian Leukosis Sarcoma Virus Genes. In: Arber, W., et al. Current Topics in Microbiology and Immunology. Current Topics in Microbiology and Immunology, vol 83. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-67087-9_1

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