Abstract
Intracranial space-occupying lesions causing direct or indirect compression of the hypothalamic structures are apt to produce severe disturbances of endocrine and general hypothalamic regulations. Neurosurgical experience confirms the important role dysregulations play for operative and postoperative survival and care. This is true also for procedures performed on the hypothalamic structures proper. Therefore an experimental study of this clinical and morphologic diencephalic syndrome appeared to be of value. Since previous investigations (4, 6, 8, 10) did not deal with clinical problems, we tried to develop an experimental model which imitates a hypothalamic space occupying lesion in the rabbit, so as to study acute and chronical hypothalamic dysfunction.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
AKERT, K.: Die Physiologie und Pathophysiologic des Hypothalamus. In: Einführung in die stereotaktischen Operationen mit einem Atlas des menschlichen Gehirns. SCHALTENBRAND, G., BAILEY, P. (eds.), Vol. 1, pp. 152–229. Stuttgart: Thieme 1959
ANDERSSON, B., GALE, C.C., HÖKFELT, B., LARSSON, B.: Akut and chronic effects of praeoptic lesions. Acta Physiol. Scand. 65, 45–60 (1965)
CARLSON, L.D.: Central and peripheral mechanisms in temperature regulation. In: The Pharmacology of Thermoregulation, pp. 7–21. Basel: Karger 1973
EULER, C. von: Temperature potentials in the hypothalamus. J. Cell Comp. Physiol. 36, 333–350 (1950)
HAMMEL, H.T.: Regulation of internal body temperature. Ann. Rev. Physiol. 30, 641–710 (1968)
HESS, W.R.: Vegetative Funktionen und Zwischenhirn. Helv. Physiol. Pharmacol. Acta 4 (Suppl.) 65 ff (1947)
HESS, R.W.: Das Zwischenhirn. 2nd ed. Basel: Schwabe 1954
NAKAYAMA, T., HAMMEL, H.T., HARDY, J.D., EISENMANN, J.S.: Thermal stimulation of electrical activity of single unit of the preoptic region. Am. J. Physiol. 204, 1122–1126 (1963)
OLIVECRONA, H.: Paraventricular nucleus and pituitary gland. Acta Physiol. Scand. 40 (Suppl.) 136 (1957)
STOLL, W.A.: Beziehungen des Hypothalamus zur Temperaturregulierung. Helv. Physiol. Acta 1, 329–357 (1943)
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1978 Springer-Verlag Berlin Heidelberg
About this paper
Cite this paper
Clar, H.E., Gerhard, L., Reinhardt, V. (1978). Experimental and Morphologic Investigations on Reversible and Irreversible Hypothalamic Compression in the Rabbit. In: Wüllenweber, R., Wenker, H., Brock, M., Klinger, M. (eds) Treatment of Hydrocephalus Computer Tomography. Advances in Neurosurgery, vol 6. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-67082-4_35
Download citation
DOI: https://doi.org/10.1007/978-3-642-67082-4_35
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-67084-8
Online ISBN: 978-3-642-67082-4
eBook Packages: Springer Book Archive