Clinical Observation, Diagnostics, and Therapy for Symptomatic and Hereditary Porphyria Cutanea Tarda

  • G. C. Topi
  • L. D’Alessandro Gandolfo

Abstract

In our experience, porphyria cutanea tarda (PCT) is the most frequently encountered porphyrinopathy in Italy. In the last 9 years, at our institute’s center for porphyrinopathy study, we have observed 203 cases of apparently symptomatic PCT and 18 cases of hereditary PCT, whereas all the other porphyrias (acute intermittent porphyria, porphyria variegata, erythropoietic protoporphyria, Giinther’s disease, hereditary erythropoietic coproporphyria) did not add up to 40 cases.

Keywords

Hepatitis Estrogen Porphyrin Bismuth Transferrin 

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References

  1. 1.
    Topi, G.C., D’Alessandro Gandolfo, L.: Aspetti matabolici ed alterazioni biochimiche della porfiria cutanea tardiva. Boll. 1st. Dermatol. S. Gallicano 7 93–112 (1971)Google Scholar
  2. 2.
    Topi, G.C., D’Alessandro Gandolfo, L. : Liver in Porphyria cutanea tarda. In: Porphyrins in Human Diseases. Doss, M. (ed.). Basel: Karger 1976, pp. 312–324Google Scholar
  3. 3.
    Topi, G.C., D’Alessandro Gandolfo, L.: Confronto fra i risultati dell’epatobiopsia ed alcune attivita enzimatiche del siero nella porfiria cutanea tarda. L.A.B. II, 229–232 (1975)Google Scholar
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    Picchiotti, R., D’Alessandro Gandolfo, L., Bandiera, G., Topi, G.C.: Evidence of a porphyrin gradient in the hepatic vein of patients with Porphyria Cutanea Tarda. Rendic. Gastroenterology 7 192–193 (1975)Google Scholar
  5. 5.
    Topi, G.C., D’Alessandro Gandolfo, L.: Inheritance of Porphyria cutanea tarda: Analysis of 14 cases in 5 families. Br. J. Dermatol. 97, 617–627 (1977)PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1978

Authors and Affiliations

  • G. C. Topi
    • 1
  • L. D’Alessandro Gandolfo
    • 1
  1. 1.Department of Experimental DermatologyIstituto S. GallicanoRomeItaly

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