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The Maternal Endocrine Pancreas

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Carbohydrate Metabolism in Pregnancy and the Newborn 1978

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Abstract

Islet hypertrophy, B–cell hyperplasia and increased B–cell granulation have been demonstrated in normal pregnancy in the rat (van Assche, 1974; Aerts and van Assche, 1975). These morphological findings correlate with the biological feature of hyperinsulinism in animal and human pregnancy (Hellman, 1960; Spellacy and Goetz, 1963; Rishi et al, 1969; Malaisse et al. , 1969; Spellacy, 1971; Green and Taylor, 1972; van Assche, 1974; Aerts and van Assche, 1975). This hyperinsulinism during pregnancy corresponds with an increased sensitivity (insulin synthesis and secretion), to glucose and other secretogogues (Green and Taylor, 1972; Fisher and Sutherland, 1975; Bone and Taylor, 1976).

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Authors
  1. F. A. Van Assche
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  2. L. Aerts
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Editor information

Editors and Affiliations

  1. Department of Obstetrics and Gynaecology, University of Aberdeen, Maternity Hospital, Foresterhill, Aberdeen, AB9 2ZD, Great Britain

    H. W. Sutherland

  2. Diabetic Out-Patient Department, Aberdeen Royal Infirmary, Woolmanhill, Aberdeen, AB9 1GS, Great Britain

    J. M. Stowers

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© 1979 Springer-Verlag Berlin Heidelberg

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Assche, F.A.V., Aerts, L. (1979). The Maternal Endocrine Pancreas. In: Sutherland, H.W., Stowers, J.M. (eds) Carbohydrate Metabolism in Pregnancy and the Newborn 1978. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-66972-9_8

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  • DOI: https://doi.org/10.1007/978-3-642-66972-9_8

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-08798-4

  • Online ISBN: 978-3-642-66972-9

  • eBook Packages: Springer Book Archive

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