Abstract
The ideal test to detect an asymptomatic disease should be specific and acutely sensitive in order to minimise false positive and false negative results. Difficulties arise from the precise definition of the zone which divides the continuous spectrum of the biological response into physiological and pathological, although the poles are usually in marked contrast. Additional stress tests may be used in an attempt to clarify the controversial marginal results adjacent to the arbitrary limits but frequently these have been found to increase the sensitivity at the expense of specificity. These general principles are particularly relevant to the detection of chemical diabetes in pregnancy.
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Sutherland, H.W., Stowers, J.M., Fisher, P.M. (1979). Detection of Chemical Gestational Diabetes. In: Sutherland, H.W., Stowers, J.M. (eds) Carbohydrate Metabolism in Pregnancy and the Newborn 1978. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-66972-9_29
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DOI: https://doi.org/10.1007/978-3-642-66972-9_29
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