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Inhibition of Cell Migration in vivo and Granuloma Formation

  • Chapter
Anti-Inflammatory Drugs

Part of the book series: Handbook of Experimental Pharmacology ((HEP,volume 50 / 2))

Abstract

Cell migration is a cardinal feature of the inflammatory response. This phenomenon is characterised by emigration of leucocytes from small blood vessels and their accumulation in inflamed or injured tissues. The early morphological event is the movement of leucocytes from the center to the periphery of the bloodstream, followed by the adhesion of the cells to the luminal surface of the vascular endothelium, especially of the postcapillary venules.

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  1. The Wellcome Research Laboratories, Langley Court, BR3 3BS, Beckenham, Kent, UK

    John R. Vane

  2. Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo, CEP 14.100, São Paulo, Brazil

    Sergio H. Ferreira

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Di Rosa, M. (1979). Inhibition of Cell Migration in vivo and Granuloma Formation. In: Vane, J.R., Ferreira, S.H. (eds) Anti-Inflammatory Drugs. Handbook of Experimental Pharmacology, vol 50 / 2. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-66891-3_9

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