A Critical Comparison of the Evaluation of Anti-Inflammatory Therapy in Animal Models and Man

  • P. J. L. Holt
Part of the Handbook of Experimental Pharmacology book series (HEP, volume 50 / 2)


This chapter is purposely written from the point of view of the practising clinician in the hope that it may illustrate some of the difficulties in moving from in vitro or animal models of inflammation to the human organism and of assessing the clinical action of anti-inflammatory agents. It is primarily concerned only with the inflammation of arthritis and associated conditions which invariably form the major indication for this form of therapy.


Rheumatoid Arthritis Systemic Lupus Erythematosus Ankylose Spondylitis Rheumatic Disease Grip Strength 
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© Springer-Verlag Berlin Heidelberg 1979

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  • P. J. L. Holt

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