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Immunological and Para-Immunological Aspects of Inflammation

  • Chapter
Book cover Inflammation

Part of the book series: Handbook of Experimental Pharmacology ((HEP,volume 50 / 1))

Abstract

Investigations into the causes of inflammatory processes in the body stem from the recognition by John Hunter that inflammation is not a disease process in its own right, and that every inflammatory process has a cause (Hunter, 1812). There is no doubt that at the present time we know more about the immunological causes of inflammation than about the mechanisms underlying the processes that, for want of a better term, are described as “non-specific” inflammatory processes. It is therefore logical to divide inflammatory mechanisms into two broad groups (1) immunological (2) non-immunological. This chapter is concerned with a review of the immunological causes of inflammation and, in addition, with those phenomena which may lack the specificity normally associated with the “specific adaptive immune response” but which use some of the pathways normally associated with immunological reactions, such as the alternative pathway of complement activation.

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Turk, J.L., Willoughby, D.A. (1978). Immunological and Para-Immunological Aspects of Inflammation. In: Vane, J.R., Ferreira, S.H. (eds) Inflammation. Handbook of Experimental Pharmacology, vol 50 / 1. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-66888-3_8

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