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Catabolism of VLDL and Removal of Cholesterol From Intact Cells

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Atherosclerosis — is it reversible?
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Abstract

Even though the formal title of this paper is limited to the catabolism of VLDL, it was very difficult to separate this from the catabolism of chylomicrons, since they may be considered to belong to the same class of lipoproteins which forms a continuous spectrum of sizes between 400 and 5000 Å. While chylomicrons are synthesized only in the jejunal cell, VLDL are produced both in the liver and in the small intestine, and the similarities of the intracellular transport and secretion of chylomicrons and VLDL were pointed out previously (12). It seems pertinent to point out that the VLDL and nascent chylomicrons secreted by the intestine do not have their full complement of apoproteins (23) and acquire them in the circulation.

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© 1978 Springer-Verlag Berlin · Heidelberg

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Stein, Y., Stein, O. (1978). Catabolism of VLDL and Removal of Cholesterol From Intact Cells. In: Schettler, G., Stange, E.F., Wissler, R.W. (eds) Atherosclerosis — is it reversible?. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-66850-0_13

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  • DOI: https://doi.org/10.1007/978-3-642-66850-0_13

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-08582-9

  • Online ISBN: 978-3-642-66850-0

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