Skip to main content

Etomidate, a New Hypnotic Agent for Intravenous Application

  • Chapter
Etomidate

Abstract

After successful animal experiments (JANSSEN et al., 1971) we investigated the hypnotic potency and the cardiovascular activity of the new substance etomidate on volunteers.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 39.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Doenicke, A.: Klinisch-Experimentelle Untersuchungen Und Erster Klinischer Erfahrungsbericht Über Ein Neues I.V. Hypnotikum. Proceedings: 6. Internationaler Fortbildungskurs Für Klinische Anaesthesiologie, Wien, 21–25. Mai 1973.

    Google Scholar 

  2. Doenicke, A., Gabany, D., Lemcke, H., Schürk-Bulich, M.: Kreislaufver- Halten Nach 3 Kurzwirkenden I.V. Hypnotika Etomidate, Propanidid, Methohexital. Anaesthesist 23, 108 (1974).

    PubMed  CAS  Google Scholar 

  3. Doenicke, A., Kugler, J.: Etomidate - Erste Klinische Prüfung Eines Neuen Intravenösen Hypnotikums. Unveröffentlicht, 1972.

    Google Scholar 

  4. Doenicke, A., Kugler, J., Penzel, G., Laub, M., Killian, I., Kalmar, L., Bezecny, H.: Hirnfunktion Und Toleranzbreite Nach Etomidate, Einem Neuen Barbituratfreien I.V. Applizierbaren Hypnotikum. Anaesthesist 22, 357 (1973).

    PubMed  CAS  Google Scholar 

  5. Doenicke, A., Lorenz, W., Beigl, R., Bezecny, H., Uhlig, G., Kalmar, L., Praetorius, B., Mann, G.: Histamine Release After Intravenous Application Of Short-Acting Hypnotics. A Comparison Of Etomidate, Althesin (T 1341) And Propanidid. Brit.J.Anaesth. 45, 1097 (1973).

    Article  PubMed  CAS  Google Scholar 

  6. Doenicke, A., Wagner, E., Beetz, K.H.: Blutgasanalysen (Arteriell) Nach Drei Kurzwirkenden I.V. Hypnotika (Propanidid, Etomidate, Methohexital). Anaesthesist 22, 353 (1973).

    PubMed  CAS  Google Scholar 

  7. Janssen, P.A.J., Niemegeers, C.J.E., Schellekens, K.H.L., Lenaerts, F.M.: Etomidate, R- (+) -Ethyl-1- K- -Methylbenzyl) Imidazole-5-Carboxylate (R 16 659), A Potent, Short-Acting And Relatively Atoxic Intravenous Hypnotic Agent In Rats. Arzneimittel-Forsch. 21, 1234 (1971).

    CAS  Google Scholar 

  8. Lorenz, W., Doenicke, A., Meyer, R., Reimann, H.J., Kusche, J., Barth, H., Gesing, H., Hutzel, M., Weissenbacher, B.: Histaminerelease in Man by Propanidid and Thiopentone: Pharmacological Effects and Clinical ConseQuences. Brit.J.Anaesth. 44 355 (1972).

    Article  PubMed  CAS  Google Scholar 

Download references

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1977 Springer Verlag Berlin Heidelberg

About this chapter

Cite this chapter

Doenicke, A. (1977). Etomidate, a New Hypnotic Agent for Intravenous Application. In: Doenicke, A. (eds) Etomidate. Anaesthesiology and Resuscitation / Anaesthesiologie und Wiederbelebung / Anesthésiologie et Réanimation, vol 106. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-66787-9_6

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-66787-9_6

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-08485-3

  • Online ISBN: 978-3-642-66787-9

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics