Etomidate pp 152-155 | Cite as

Etomidate as “A New Drug in Intravenous Anaesthesia” (Conclusion)

  • A. Doenicke
Part of the Anaesthesiology and Resuscitation / Anaesthesiologie und Wiederbelebung / Anesthésiologie et Réanimation book series (A+I, volume 106)


Since March 1972, etomidate has been taken on clinical trial. Metabolism occurs quickly. Up to now, there was no evidence of histamine release or immunodepressant effect either in biochemical investigations or in clinical tests. A final conclusion, however, should only be made after many years of clinical experience. As shown in the EEG, the deep stages of narcosis are similar to those of barbiturates. The absence of analgesia and frequency of myocloni during etomidate narcosis make us assume that, unlike with barbiturates, there is no inhibition of the thalamic (diencephalic) region or of any subthalamic structures.


Propylene Glycol Histamine Release Peripheral Vascular Resistance Sulfate Salt Intravenous Anaesthesia 
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Copyright information

© Springer Verlag Berlin Heidelberg 1977

Authors and Affiliations

  • A. Doenicke

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