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Production of Extracellular Matrix by Notochord and by Spinal Cord

  • Brian K. Hall
Chapter
  • 22 Downloads
Part of the Advances in Anatomy, Embryology and Cell Biology/ Ergebnisse der Anatomie und Entwicklungsgeschichte/ Revues d’anatomie et de morphologie expérimentale book series (ADVSANAT, volume 53/4)

Abstract

The evident role which notochord and spinal cord play in evoking somitic condrogenesis in vivo, and the accumulating evidence that normal constituents of the extracellular matrix of cartilage (chondroitin sulphate, collagen, hyaluronate) could influence the rate of synthesis of cartilage extracellular matrix by feedback inhibition and stimulation (Hall, 1973), lead to a search for the existence of extracellular matrices around the notochord and spinal cord. The first studies bearing on this problem utilized histochemical and autoradiographic techniques to show that glycosaminoglycans could be visualised around the notochord at the time when chondrogenesis was commencing within the adjacent sclerotome.

Keywords

Spinal Cord Hyaluronic Acid Chondroitin Sulphate Chick Embryo Embryonic Chick 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag Berlin-Heidelberg 1977

Authors and Affiliations

  • Brian K. Hall
    • 1
  1. 1.Department of Biology, Life Sciences CentreDalhpusie UniversityHalifaxCanada

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