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As mentioned in section 2.1. (pp. 13-14) the early studies in the 1920’s, 30’s, and 40’s which involved grafting of somites dissected from chick embryos onto the CAM involved the transfer or adjacent ectoderm and possibly of subjacent endoderm within the grafts. This problem has been taken up by later workers in an endeavour to determine whether the ectoderm which normally overlies the developing somite plays any role in the induction of the cartilage which forms in the sclerotome. The results are contradictory and the final story is not yet told. However, it is evident that no action is exerted by these epithelia in vivo for chondrogenesis fails to occur after extirpation of the spinal cord and/or notochord. The epithelia cannot overcome this loss.
KeywordsSpinal Cord Chick Embryo Inductive Ability Otic Vesicle Mullenan Duct
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