A Functional Estimate of the Local PO2 at Aortic Chemoreceptors

  • A. S. Paintal
Conference paper


The tissue PO2 at any point in a tissue mass is determined by the distance of the point from the capillaries, its metabolic activity, and oxygen availability (i.e., oxygen content of the blood and blood flow). Variation in local blood flow and the level of metabolic activity will determine the level of tissue PO2 at different points in the tissue mass. This should also apply to the aortic and carotid bodies. Indeed, direct measurements of tissue PO2 have releaved that it is different in different parts of the carotid body (1,2,18,19). In addition, as was concluded earlier (12), Whalen and Nair have shown that the external environment has an obvious influence on tissue PO2 of the exposed carotid body. This is particularly obvious if the blood flow to the carotid body is greatly reduced (18,19).


Carotid Body Local Blood Flow Glomus Cell Functional Estimate Normal Body Temperature 
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© Springer-Verlag Berlin · Heidelberg 1977

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  • A. S. Paintal

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