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Histofluorescent and Ultrastructural Studies on the Effects of Reserpine and Calcium on Dense-Cored Vesicles in Glomus Cells of the Rat Carotid Body

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Abstract

The dense-cored vesicles of the glomus cells of the carotid body are presumably the storage site of neurotransmitter substances because of the similarity in appearance of these granules to those found in catecholamine-storing sites of other cells. In addition, the glomus cells fluoresce strongly after exposure to hot paraformaldehyde vapor, and this formaldehyde-induced fluorescence (2) is a specific histochemical test indicating the presence of monoamines. The greenish yellow color of the fluorescent glomus cells, in contrast to the more brilliant yellow of the serotonin-containing surrounding mast cells, indicates that the glomus cells contain catecholamines.

The author’s investigations are supported by research grant NS-07662 from the National Institutes of Health, U.S. Public Health Service. Dr. E.S. Hearney collaborated on the morphometric studies, to be published in detail elsewhere.

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Authors

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H. Acker S. Fidone D. Pallot C. Eyzaguirre D. W. Lübbers R. W. Torrance

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© 1977 Springer-Verlag Berlin · Heidelberg

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Hess, A. (1977). Histofluorescent and Ultrastructural Studies on the Effects of Reserpine and Calcium on Dense-Cored Vesicles in Glomus Cells of the Rat Carotid Body. In: Acker, H., Fidone, S., Pallot, D., Eyzaguirre, C., Lübbers, D.W., Torrance, R.W. (eds) Chemoreception in the Carotid Body. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-66755-8_28

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  • DOI: https://doi.org/10.1007/978-3-642-66755-8_28

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-08455-6

  • Online ISBN: 978-3-642-66755-8

  • eBook Packages: Springer Book Archive

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