Recent Advances in the Field of Antibiotics

  • Ch. Tamm
Part of the Proceedings in Life Sciences book series (LIFE SCIENCES)

Abstract

Antibiotics are secondary metabolites of microorganisms. Therefore, they are defined as compounds which are not involved in the growth of the producing microorganisms. They take part neither in the formation of cell walls nor contribute to the energy balance of the organism. One can designate an antibiotic as a secondary microbial metabolite which is capable of inhibiting the growth of another microorganism or even destroying it (cf. Waksman, 1945). The discovery of the penicillins and shortly thereafter the streptomycins, before and during the second world war, initiated the aera of “chemical microbiology” and, as a logical consequence, the development of the new field of “microbial technology.” As a result of worldwide efforts on both basic research and technical development a great variety of new substances have been produced, which proved useful for human and veterinary medicine. For details reference is made to some selected monographs which describe the development of the past decade (Evans, 1965; Vaněk and Hŏstálek, 1965; Korzybski et al., 1967; Gottlieb and Shaw, 1967a,b; Kadis et al., 1971a,b,c; Reiner, 1974; Corcoran and Hahn, 1975).

Keywords

Streptomyces Trichoderma Macrolide Adriamycin Sesquiterpene 

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© Springer-Verlag Berlin Heidelberg 1977

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  • Ch. Tamm

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