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The Modification of Natural Substances in the Modern Drug Synthesis

  • Conference paper
New Natural Products and Plant Drugs with Pharmacological, Biological or Therapeutical Activity

Part of the book series: Proceedings in Life Sciences ((LIFE SCIENCES))

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Abstract

Drugs are remedies which are thought to intervene in disturbed biochemical processes and to repair them.

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References

  1. Chain, E. Sir: Immunologie und Gesellschaft. Schwick, H.G. (ed.). Stuttgart: Wissenschaftliche Verlagsgesell., 1975

    Google Scholar 

  2. Index Nominum 1975/76: Zürich: Wissenschaftliche Zentralstelle des Schweizer Apotheker-Vereins, 1975

    Google Scholar 

  3. Wichtl, M.: Wirkstoffsynthese im lebenden Organismus und im Laboratorium, ein Vergleich. Pharmazie in unserer Zeit 2, 33 (1976). IMS-Liste 1. Hj. 1976

    Article  Google Scholar 

  4. Goto, T., Ito, S., Nakanishi, K., Natori, S., Nozoe, S.: Natural Products Chemistry. Tokyo: Kodansha Ltd.; 1974, Vol. I, pp. 450

    Google Scholar 

  5. Goto, T., Ito, S., Nakanishi, K., Natori, S., Nozoe, S.: Natural Products Chemistry. London-New York: Academic Press, 1974, Vol. I, pp. 450

    Google Scholar 

  6. Horton, E.W.: Prostaglandins. Berlin-Heidelberg-New York: Springer, 1972

    Google Scholar 

  7. Goto, T., Ito, S., Nakanishi, K., Natori, S., Nozoe, S.: Natural Products Chemistry. Tokyo: Kodansha Ltd.; 1974, Vol. II, pp. 33

    Google Scholar 

  8. Goto, T., Ito, S., Nakanishi, K., Natori, S., Nozoe, S.: Natural Products Chemistry. London-New York: Academic Press, 1974, Vol. II, pp. 33

    Google Scholar 

  9. Hambrecht, B.: Neuronenmodelle. Angew. Chem. 7, 211 (1976)

    Article  Google Scholar 

  10. Tamm, Ch.: Recent Advances in the field of antibiotics. Cf. this edition

    Google Scholar 

  11. Firmenschrift Merck and Co. Inc., Scrip. 29. Nov. 1975, 10

    Google Scholar 

  12. Bretschneider, H., Vetter, W.: Eine Synthese des D,L-4-Amino-3-isoxazolidons (D,L-Cydoserins). Monatsir. Chem. 4–5, 625 (1958)

    Article  Google Scholar 

  13. USP 3956–302 (1974), DT-OS 2522–090 (1976)

    Google Scholar 

  14. Jolies, P.: Hydrosoluble immunstimulants of bacterial and synthetic origins. Experientia 32, 677 (1976)

    Article  Google Scholar 

  15. Auterhoff, H.: Lehrbuch der pharmazeutischen Chemie. Stuttgart: Wissenschaftliche Verlagsgesell., 1976

    Google Scholar 

  16. Mutschier, E.: Arzneimittelwirkungen. Stuttgart: Wissenschaftliche Verlagsgesell., 1975

    Google Scholar 

  17. Manske, R.H.F.: The Alkaloids. New York-London: Academic Press, 1965

    Google Scholar 

  18. Drug by Sandoz Ltd.

    Google Scholar 

  19. BE 787026 (DT-OS 2138517)

    Google Scholar 

  20. Drug by Hoechst Ltd.

    Google Scholar 

  21. Makleit, S.: Acta Universitatis Debreceniensis de Ludovico Kossuth nominatae Series physica et chimica 265 (1972–1973)

    Google Scholar 

  22. Bognár, R., Géza, H., György, G., Peter, K., Zsigmond, D.: Acta Pharm. Hung. 43, 169 (1973)

    PubMed  Google Scholar 

  23. Bognár, R., Makleit, S.: Acta Chim. Acad. Sci. Hung. 58 (2), 203 (1968)

    Google Scholar 

  24. Fürst, Z., Knoll, J.: Acta Physiol. Acad. Sci. Hung. 41, 366 (1972)

    Google Scholar 

  25. Fürst, S., Knoll, J., Makleit, S.: The Pharmacologie of 14-hydroxy-azidomorphin. J. Pharm. Pharmac. 27, 99 (1975)

    Article  Google Scholar 

  26. Knoll, J.: Azidormorphin and Rymazolium. An approach to the ideal analgesic. Pharmacol. Res. Commun. 5, 175 (1973)

    Article  CAS  Google Scholar 

  27. Graf, L.: FEBS Lett. 64, (I) 181 (1976)

    Article  PubMed  CAS  Google Scholar 

  28. USP 3.944.673

    Google Scholar 

  29. Granchelli, F.E., Keller, J.K., Pars, H.G., Razdan, R.K.: Drugs derived from cannabinoids. 1. Nitrogen analogs, benzopyranopyridines and benzopyranopyrroles. J. Med. Chem. 19, 445 (1976)

    Article  PubMed  Google Scholar 

  30. Dalzell, H.C., Handrick, G.R., Howes, J.F., Pars, H.G., Razdan, R.K., Terris, B.Z.: Drugs derived from cannabinoids. 3.iasulfur analogs, ibthiopyranobenzopyrans and thienobenzopyrans. J. Med. Chem. 19, 548 (1976)

    Google Scholar 

  31. Cannabinoid research may yield new drugs. Chem. and Eng. News 15 (Washington), Sept. 30 (1974)

    Google Scholar 

  32. DT-OS 2415698

    Google Scholar 

  33. DT-OS 2322960

    Google Scholar 

  34. Loew, P., Arigoni, D.: The Biological Conversion of Loganin into Indole Alkaloids. Chem. Commun. 137 (1968)

    Google Scholar 

  35. Battersby, A.R., Burnet, A.R., Parsons, P.G.: Alkaloid Biosynthesis. J. Chem. Soc. C 1187 (1969)

    Google Scholar 

  36. Scott, A.I., Wright, I.G.: Chem. Commun. 537 (1965)

    Google Scholar 

  37. Battersby, A.R., Byrne, J.C., Kapil, R.S., Martin, J.A., Payne, T.G., Arigoni, D., Loew, P.: The Mechanism of Indole Alkaloid Biosynthesis. Chem. Commun. 951 (1968)

    Google Scholar 

  38. Luckner, M.: Der Sekundär-Stoffwechsel in Pflanze und Tier. Stuttgart: Fischer, 1969)

    Google Scholar 

  39. Thies, P.W.: Pharmacognosy and Phytochemistry. Berlin-Heidelberg-New York: Springer, 1971

    Google Scholar 

  40. Thies, P.W., Asai, A.: DT-OS 2129507 (1971, 1972)

    Google Scholar 

  41. Thies, P.W., Asai, A.: Notiz über eine vereinfachte Synthese von 2,9-Dioxatricyclo [4,3,1,O3’7] decanen aus Didrovaltratum. Chem. Ber. 105, 3491 (1972)

    Article  CAS  Google Scholar 

  42. Thies, P.W.: DT — OS 2306118 (1973, 1974)

    Google Scholar 

  43. Thies, P.W., Finner, E., Rosskopf, R.: Über die Wirkstoffe des Baldrians — X. Tetrahedron 29, 3213 (1973)

    Article  CAS  Google Scholar 

  44. Inouye, H., Ueda, S., Uesato, S., Shingu, T., Thies, P.W.: Die absolute Konfiguration von Valerosidatum und von Didrovaltratum. Tetrahedron 30, 2317 (1974)

    Article  CAS  Google Scholar 

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Authors
  1. P. W. Thies
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Editors and Affiliations

  1. Institut für Pharmazeutische Arzneimittellehre, Universität München, Karlstraße 29, 8000, München 2, Germany

    H. Wagner  & P. Wolff  & 

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© 1977 Springer-Verlag Berlin Heidelberg

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Thies, P.W. (1977). The Modification of Natural Substances in the Modern Drug Synthesis. In: Wagner, H., Wolff, P. (eds) New Natural Products and Plant Drugs with Pharmacological, Biological or Therapeutical Activity. Proceedings in Life Sciences. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-66682-7_12

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  • DOI: https://doi.org/10.1007/978-3-642-66682-7_12

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-66684-1

  • Online ISBN: 978-3-642-66682-7

  • eBook Packages: Springer Book Archive

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