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Radioimmuno-Screening Methods for Secondary Plant Products

  • E. W. Weiler
Part of the Proceedings in Life Sciences book series (LIFE SCIENCES)

Abstract

Since the pioneering work of Haberlandt in 1892, development in the field of plant cell culture has advanced to the point where bio-technological applications are now widely discussed. Among many others, the production of secondary plant products in cell cultures is one of the main points of interest (17). Originally it was found that a variety of typical secondary plant constituents are, under suitable conditions, formed in cell callus and suspension cultures (14). However, more recently it has been shown that in some special cases, the productivity of the cultured-cell system may even exceed that of the differentiated plants (21).

Keywords

Plant Cell Culture Indole Alkaloid Antigen Fraction Secondary Plant Product Ammonium Sulphate Solution 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. 1.
    Bancher, E., Prey, T., Wurst, F.: Eine neue Methode zur quantitativen Bestimmung einiger wichtiger Glykoside in Drogenextrakten von Digitalis lanata. Planta Medica 29, 393–399 (1976)PubMedCrossRefGoogle Scholar
  2. 2.
    Berson, S.A., Yalow, R.S.: Recent studies on insulin-binding antibodies. Ann. N.Y. Acad. Sci. 82, 338–344 (1959)PubMedCrossRefGoogle Scholar
  3. 3.
    Bertler, A., Redfors, A.: An improved method of estimating digoxin, in human plasma. Clin. Pharmacol. Ther. 11, 665–673 (1970)PubMedGoogle Scholar
  4. 4.
    Burnett, G.H., Conklin, R.L.: The enzymatic assay of plasma digoxin. J. Lab. Clin. Med. 78, 779–784 (1971)PubMedGoogle Scholar
  5. 5.
    Castle, M.C.: Isolation and quantitation of picomole quantities of digoxin, digitoxin and their metabolites by high pressure liquid chromatography. J. Chroma-togr. 115, 437–445 (1975)CrossRefGoogle Scholar
  6. 6.
    Hammerstein, F., Kaiser, F.: Quantitative Direktauswertung von Arzneipflanzenextrakten auf Dünnschichtchromatogrammen. Planta Medica 21, 5–15 (1972)PubMedCrossRefGoogle Scholar
  7. 7.
    Kaiser, F.: Chromatographische Analyse der herzwirksamen Glykoside von Digitalis-Arten. Arch. Pharmazie 299, 263–274 (1966)CrossRefGoogle Scholar
  8. 8.
    Landon, J., Moffat, A.C.: The radioimmunoassay of drugs. Analyst 101, 225–243 (1976)PubMedCrossRefGoogle Scholar
  9. 9.
    Marschner, I., Dobry, E., Erhard, F., Landersdorfer, T., Popp, B., Ringel, C., Scriba, P.C.: Berechnung radioimmunologischer Funktionen mittels spline-Funk-tionen. Ärztl. Lab. 20, 184–191 (1974)Google Scholar
  10. 10.
    Melchers, G., Labib, G.: Die Bedeutung haploider höherer Pflanzen für Pflanzenphysiologie und Pflanzenzüchtung. Ber. Deut. Botan. Ges. 82, 129–150 (1970)Google Scholar
  11. 11.
    Nassau, E., Parsons, E.R.: Detection of antibodies to Mycobacterium tuberculosis by solid phase radioimmunoassay. J. Immun. Meth. 6, 261–271 (1975)CrossRefGoogle Scholar
  12. 12.
    Nieschlag, E., Wickings, E.J.: A review of radioimmunoassay for steroids. Z. Klin. Chem. Klin. Biochem. 13, 261–271 (1975)PubMedGoogle Scholar
  13. 13.
    Pötter, H., Bärisch, H.: Versuche zur dünnschichtchromatographischen Bestimmung der Digitalis-Glykoside. Pharmazie 26, 315–318 (1971)Google Scholar
  14. 14.
    Puhan, Z., Martin, S.M.: The industrial potential of plant cell culture. Progress Indust. Microbiol. 9, 14–39 (1971)Google Scholar
  15. 15.
    Reinhard, E., Boy, M., Kaiser, F.: Umwandlung von Digitalis-Glykosiden durch Zellsuspensionskulturen. Planta Medica Suppl. 163–169 (1975)Google Scholar
  16. 16.
    Smith, T.W., Butler, V.P., Jr., Haber, E.: Characterization of antibodies of high affinity and specificity for the Digitalis glycoside digoxin. Biochemistry 9, 331–337 (1970)PubMedCrossRefGoogle Scholar
  17. 17.
    Teuscher, E.: Probleme der Produktion sekundärer Pflanzenstoffe mit Hilfe von Zellkulturen. Pharmazie 28, 6–18 (1973)PubMedGoogle Scholar
  18. 18.
    Watson, E., Calman, S.M.: Assay of digoxin in plasma by gas chromatography. J. Chromatogr. 56, 209–218 (1971)PubMedCrossRefGoogle Scholar
  19. 19.
    Weiler, E.W., Zenk, M.H.: Radioimmunoassay for the determination of digoxin and related compounds in Digitalis lamata. (1977, in press)Google Scholar
  20. 20.
    Zenk, M.H.: Haploids in physiological and biochemical research. In: Proc. Intern. Symp. Haploids in Higher Plants. Univ. Guelph, 1974, pp. 339–352Google Scholar
  21. 21.
    Zenk, M.H., El-Shagi, H., Schulte, U.: Anthraquinone production by cell suspensions cultures of Morinda eitrifolia. Planta Medica, Suppl. 79–101 (1975)Google Scholar
  22. 22.
    Zenk, M.H., El-Shagi, H., Arens, H., Stöckigt, J., Weiler, E.W., Deus, B.: Formation of the indole alkaloids serpentine and ajmalicine in cell suspension cultures of Catharanthus roseus. This volumeGoogle Scholar

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© Springer-Verlag Berlin Heidelberg 1977

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  • E. W. Weiler

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