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Introduction

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Iatrogenic Carcinogenesis

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Abstract

In recent years iatrogenic carcinogenesis has become an important field of iatrogenic pathology (Geyer, 1955; Druckrey, 1956; Schmäht, 1959; 1972; Uehlinger, 1961; Olbert, 1962; Lampert, 1964; Spain et al., 1967; Truhaut, 1967; Belpomme et al., 1972; Thomas, 1972; Goertt1er, 1972; Karrer and Wrba, 1972; Clayson, 1972; Waldenström, 1974; Deichmann, 1975; Preussmann, 1975). It is difficult to establish a relation between a specific therapy and the occurrence of a tumor, because these tumors often have latency periods of several years or even decades and because man is exposed continuously to various environmental carcinogenic factors. Therefore a syncarcinogenic action of both a specific drug and various other carcinogens has to be considered in most cases.

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References

  • Araki, M., Oshiro, K.: Papillary adenocarcinoma of the thyroid developing after treatment of hyperthyroidism with 131 I. Gann 61, 267 (1970)

    PubMed  CAS  Google Scholar 

  • Baker, H. W.: Anaplastic thyroid cancer twelve years after radioiodine therapy. Cancer (Philad.) 23, 885 (1969)

    Article  CAS  Google Scholar 

  • Belpomme, D., Blondel, P., Mathé, G.: Les cancers d’origine thérapeutique. Vie. Med. Canada Franc. 1, 140 (1972)

    CAS  Google Scholar 

  • Bross, D. J., Natarajan, N.: Risk of leukemia in suspectible children exposed to preconception, in utero and postnatal radiation. Prey. Med. 3, 361 (1974)

    Article  CAS  Google Scholar 

  • Burke, G., Levinson, M. J., Zitman, I.: Thyroid carcinoma ten years after sodium iodide I 131 treatment. J. Amer. Med. Ass. 199, 247 (1967)

    Article  CAS  Google Scholar 

  • Clayson, D. B.: Carcinogenic hazards due to drugs. In: Drug-Induced Diseases. Meyler, L., Peck, H. M. (eds.) Amsterdam: Excerpta Medica, 1972, Vol. IV, pp. 91–109

    Google Scholar 

  • Deichmann, W. B.: Cummings Memorial Lecture, 1975. J. Amer. Ind. Hyg. Ass. 33, 411 (1975)

    Article  Google Scholar 

  • Druckrey, H.: Krebserzeugende Eigenschaften bei Arzneimitteln. Muench. med. Wschr. 98, 295 (1956)

    CAS  Google Scholar 

  • Geyer, A.: Zur Frage der iatrogenen Krebse. Z. inn. Med. 10, 685 (1955)

    CAS  Google Scholar 

  • Goerttler, K.: Modell und Wirklichkeit der iatrogenen Carcinogenese. Verh. Dtsch. Ges. Path. 56, 138 (1972)

    CAS  Google Scholar 

  • Karrer, K., Wrba, H.: Bedeutung der iatrogenen Cancerogenese. Verh. Dtsch. Ges. Path. 56, 164 (1972)

    CAS  Google Scholar 

  • Lampert, F.: latrogene Schäden. Med. Klin. 59, 1001 (1964)

    PubMed  CAS  Google Scholar 

  • McDougall, I. R., Kennedy, J. S., Thomson, J. A.: Thyroid carcinoma following iodine-131 therapy. Report of a case and review of the literature. J. Clin. Endocr. 33, 287 (1971)

    Article  PubMed  CAS  Google Scholar 

  • Miller, R. W.: Radiation induced cancer. J. Nat. Cancer Inst. 49, 1221 (1972)

    PubMed  CAS  Google Scholar 

  • Modan, B., Lilienfeld, A. M.: Leukaemogenic effect of ionising-irradiation treatment in polycythaemia. Lancet 2, 439 (1964)

    Article  Google Scholar 

  • Mole, R. H.: Late effects of radiation: Carcinogenesis. Brit. Med. Bull. 29, 78 (1973)

    PubMed  CAS  Google Scholar 

  • Olbert, Th.: latrogene Karzinogene. Krebsarzt 17, 154 (1962)

    PubMed  CAS  Google Scholar 

  • Pack, C. T., Davis, J.: Radiation cancer of the skin. Radiology 84, 436 (1965)

    PubMed  CAS  Google Scholar 

  • Phillips, T. L., Sheline, G. E.: Bone sarcoma following radiation therapy. Radiology 81, 992 (1963)

    PubMed  CAS  Google Scholar 

  • Preussmann, R.: Chemische Carcinogene in der menschlichen Umwelt. In: Handbuch der allgemeinen Pathologie. Geschwülste/Tumors II. Altmann, H.-W., Büchner, F., Cottier, H., Grundmann, E., Holle, G., Letterer, E., Masshoff, W., Meesen H., Roulet, F., Seifert, G., Siebert, G. (eds.) Berlin-Heidelberg-New York: Springer, 1975, Vol. 6, Part 6, pp. 421–594

    Google Scholar 

  • Schmähl, D.: Gibt es krebserzeugende Arzneimittel? Mentor Medici 18, 343 (1959)

    Google Scholar 

  • Schmähl, D.: Toxikologische Probleme der iatrogenen Carcinogenese. Verh. Dtsch. Ges. Path. 56, 133 (1972)

    Google Scholar 

  • Seydel, H. G.: The risk of tumor induction in man following medical irradiation for malignant neoplasm. Cancer (Philad.) 35, 1641 (1975)

    Article  CAS  Google Scholar 

  • Sheline, G. E., Lindsay, S., Bell, H. G.: Occurrence of thyroid nodules in children following therapy with radioiodine for hyperthyroidism. J. Clin. Endocr. 19, 127 (1959)

    Article  PubMed  CAS  Google Scholar 

  • Silva Horta, D. A. J., Abatt, J. D., Cayolla da Motta, L., Roriz, M. L.: Malignancy and other late effects following administration of thorotrast. Lancet 2, 201 (1965)

    Article  Google Scholar 

  • Spain, D. M., Kowal, S. J., Lunger, M., Shapiro, A., Slatkin, M. R., Warwhaw, L. J.: Iatrogene Krankheiten. Stuttgart: Georg Thieme 1967

    Google Scholar 

  • Staffurth, J. S.: Thyroid cancer after 131 I therapy for thyrotoxicosis. Brit. J. Radiol. 39, 471 (1966)

    Article  PubMed  CAS  Google Scholar 

  • Thomas, C.: Systematik der iatrogenen Cancerogenese. Verh. Dtsch. Ges. Path. 56, 126 (1972)

    CAS  Google Scholar 

  • Totten, R. S., Antypas, P. G., Supertius, S. M., Gaisford, J. C., White, W. L.: Pre-existing roentgen-ray dermatitis in patients with skin cancer. Cancer (Philad.) 10, 1024 (1957)

    Article  CAS  Google Scholar 

  • Truhaut, R. (ed.): Potential carcinogenic hazards from drugs. UICC Monograph Series, Vol. VII, Berlin-Heidelberg-New York: Springer 1967

    Google Scholar 

  • Uehlinger, E.: Pathologische Anatomie der Therapieschäden. Verh. Dtsch. Ges. inn. Med. 67, 457 (1961)

    Google Scholar 

  • Waldenström, J. G.: Iatrogene maligne Zustände. Med. Welt 25, 669 (1974)

    PubMed  Google Scholar 

  • Wegener, K., Wesch, H., Kampmann, H.: Retikuloendotheliales System und Thorotrastose nach diagnostischer Angiographie. Dtsch. med. Wschr. 96, 1977 (1971)

    Article  PubMed  CAS  Google Scholar 

  • Wenz, W.: Thorotrasttumoren. Quantitative Untersuchungen über das Dosis-Wirkungs-problem bei Thorotrastose. Ergebn. Chir. 46, 81 (1964)

    CAS  Google Scholar 

Download references

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Authors and Affiliations

  1. Institut für Toxikologie und Chemotherapie, Deutsches Krebsforschungszentrum, Im Neuenheimer Feld 280, D-6900, Heidelberg, Deutschland

    Professor Dr. Dietrich Schmähl

  2. Pathologisches Institut, Universität Freiburg, Albertstr. 19, D-7800, Freiburg i. Br., Federal Republic of Germany

    Professor Dr. Carlos Thomas & Dr. Rolf Auer

Authors
  1. Professor Dr. Dietrich Schmähl
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  2. Professor Dr. Carlos Thomas
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  3. Dr. Rolf Auer
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© 1977 Springer-Verlag Berlin · Heidelberg

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Schmähl, D., Thomas, C., Auer, R. (1977). Introduction. In: Iatrogenic Carcinogenesis. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-66630-8_1

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  • DOI: https://doi.org/10.1007/978-3-642-66630-8_1

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-08200-2

  • Online ISBN: 978-3-642-66630-8

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