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Sodium Nitroprusside Induced Hypotension and Isovolemic Hemodilution in Dogs

  • J. C. Boon
  • F. Jesch
  • W. J. Stelter
  • K. Messmer
Conference paper
Part of the Langenbecks Archiv für Chirurgie, Supplement 1977 book series (DTGESCHIR, volume 77)

Abstract

Sodium nitroprusside (SNP), an extremely potent hypotensive agent, is becoming increasingly popular for use during anaesthesia to provide a bloodless field for a variety of surgical procedures. In recent years there is also growing interest in preoperative normovolemic hemodilution, a newly developed method to reduce the need for homologous blood transfusions and their concomitant hazards. So far, one can merely speculate about the consequences of combining these two procedures. In this study the hemodynamic effects of SNP induced by hypotension in hemodiluted and in non-hemodiluted dogs were therefore investigated.

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Literatur

  1. 1.
    Messmer, K.: Hemodilution. Surg. Clin. N. Amer. 55, 659–678 (1975)PubMedGoogle Scholar
  2. 2.
    Vesey, C.J., Cole, P.V., Simpson, P.J.: Cyanide and Thiocyanate Concentrations following Sodium Nitroprusside Infusion in Man. Brit. J. Anaesth. 48, 651–660 (1976)PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag Berlin · Heidelberg 1977

Authors and Affiliations

  • J. C. Boon
    • 2
  • F. Jesch
    • 1
  • W. J. Stelter
    • 1
  • K. Messmer
    • 1
  1. 1.Institute for Surgical Research, Dept. of SurgeryUniversity of MunichGermany
  2. 2.Institute for Surgical Research, Dept. of SurgeryUniversity of MunichMunichGermany

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