Sodium Nitroprusside Induced Hypotension and Isovolemic Hemodilution in Dogs
Sodium nitroprusside (SNP), an extremely potent hypotensive agent, is becoming increasingly popular for use during anaesthesia to provide a bloodless field for a variety of surgical procedures. In recent years there is also growing interest in preoperative normovolemic hemodilution, a newly developed method to reduce the need for homologous blood transfusions and their concomitant hazards. So far, one can merely speculate about the consequences of combining these two procedures. In this study the hemodynamic effects of SNP induced by hypotension in hemodiluted and in non-hemodiluted dogs were therefore investigated.
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