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Neuropharmacology and Neurochemistry of Subjective Effects, Analgesia, Tolerance, and Dependence Produced by Narcotic Analgesics

  • Chapter
Drug Addiction I

Abstract

The purposes of this chapter are: (1) to discuss the subjective effects and behavioral correlates, analgesia, and the tolerance and dependence-producing properties of the narcotic analgesics and to relate these changes to their abuse, (2) to review the neurophysiologic and neurochemical literature which bear upon the site and mode of action of narcotic analgesics, and (3) to speculate on the nature of the heroin abuse problem as it relates to the actions of the narcotic analgesics, as well as on areas of research which may lead to the identification of salient psychopathologic processes in the addict.

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Martin, W.R., Sloan, J.W. (1977). Neuropharmacology and Neurochemistry of Subjective Effects, Analgesia, Tolerance, and Dependence Produced by Narcotic Analgesics. In: Martin, W.R. (eds) Drug Addiction I. Handbuch der experimentellen Pharmakologie / Handbook of Experimental Pharmacology, vol 45 / 1. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-66612-4_2

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