Abstract
The pathogenetic mechanisms responsible for the primary lesions in systemic lupus erythematosus (SLE) have been clarified by recent research; however, the cause of this complex autoimmune disease remains elusive. Much of what is understood about the development of SLE has been learned from studies of the two animal species which spontaneously develop the disease, inbred strains of New Zealand mice and dogs. The purpose of this report is to summarize the information gained from studying the canine form of the disease and to illustrate its relevance to the study of human SLE.
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Lewis, R.M. (1977). Evidence for a Virus in Canine Systemic Lupus Erythematosus. In: Glynn, L.E., Schlumberger, H.D. (eds) Experimental Models of Chronic Inflammatory Diseases. Bayer-Symposium, vol 6. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-66573-8_9
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DOI: https://doi.org/10.1007/978-3-642-66573-8_9
Publisher Name: Springer, Berlin, Heidelberg
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