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Pathology of Lymphoid Tissue in Rheumatoid Arthritis and Allied Diseases

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Experimental Models of Chronic Inflammatory Diseases

Part of the book series: Bayer-Symposium ((BAYER-SYMP,volume 6))

Abstract

Rheumatoid arthritis (R.A.) and such allied disease as lupus erythematosis and Sjögren’s syndrome are generally classified as chronic inflammatory autoimmune disorders. Evidence for a chronic stimulus to the immune system in these disorders is supported by the proliferation of cells of the lymphoreticular system which manifests itself clinically by enlargement of the lymph nodes, at times by splenomegaly, and by the formation of excessive amounts of immunoglobulins. In addition, histologic evidence of lymphoid proliferation may be seen outside the lymphoreticular system: in the synovium of joints; in the bone marrow; and, particularly in Sjögren’s syndrome, in such organs as the lungs and kidneys.

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Authors
  1. B. Schnitzer
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Editors and Affiliations

  1. The Mathilda and Terence Kennedy Institute of Rheumatology, Bute Gardens, Hammersmith, London, W6 7DW, Great Britain

    Leonard Eleazar Glynn

  2. Bayer Pharma-Forschungszentrum, Institut für Immunologie und Onkologie, Aprather Weg, 5600, Wuppertal 1, Fed. Rep. of Germany

    Horst Dieter Schlumberger

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© 1977 Springer-Verlag

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Schnitzer, B. (1977). Pathology of Lymphoid Tissue in Rheumatoid Arthritis and Allied Diseases. In: Glynn, L.E., Schlumberger, H.D. (eds) Experimental Models of Chronic Inflammatory Diseases. Bayer-Symposium, vol 6. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-66573-8_25

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  • DOI: https://doi.org/10.1007/978-3-642-66573-8_25

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-66575-2

  • Online ISBN: 978-3-642-66573-8

  • eBook Packages: Springer Book Archive

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