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The Regulation of the Participation of Mononuclear Phagocytes in Inflammatory Responses

  • R. van Furth
  • D. van Waarde
  • J. Thompson
  • A. E. Gassmann
Part of the Bayer-Symposium book series (BAYER-SYMP, volume 6)

Abstract

The main function of macrophages is to eliminate deleterious material by phagocytosis or pinocytosis. These cells can ingest microorganisms, neoplastic cells, effete cells, cell debris, antigen-antibody complexes, etc. (6, 8, 9, 16, 34, 35, 36, 37, 43, 50). In addition, macrophages produce and secrete a large number of biologically important substances such as pyrogens, lysosomal hydrolases, lysozyme, complement factors (C2 and C3), plasminogen activators, and prostaglandin (E2), as well as collagenase and elastase, two enzymes that play a role in the healing of a lesion (10, 13, 31, 38, 39, 49).

Keywords

Peritoneal Cavity Label Index Peritoneal Macrophage Mononuclear Phagocyte Peripheral Blood Monocyte 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag 1977

Authors and Affiliations

  • R. van Furth
  • D. van Waarde
  • J. Thompson
  • A. E. Gassmann

There are no affiliations available

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