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Pharmakologische Effekte und Wechselwirkungen von Prämedikationsund Narkosemitteln auf die Atmung

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Der Risikopatient in der Anästhesie

Part of the book series: Klinische Anästhesiologie und Intensivtherapie ((KAI,volume 12))

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Zusammenfassung

Beschränken wir das Thema auf die klinisch zu erfassenden und meßbaren Parameter “Ventilation und Blutgase”, so könnten die pharmakologischen Effekte der in Frage kommenden Arzneimittel in Form tabellarischer Übersichten wiedergegeben werden.

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Literatur

  1. BELLVILLE, J. W., HOWLAND, W. S., SEED, J. C., HOODE, R. W.: The effect of sleep on the respiratory response to carbon dioxide. Anesthesiology 20, 628 (1959).

    Article  PubMed  CAS  Google Scholar 

  2. BERKOWITZ, B. A., ASLING, J. H., SHNIDER, S. M., WAY, E. L.: Relationship of pentazocine plasma levels to pharmacological activity in man. Clin. Pharmacol. Ther. 10, 320 (1969).

    PubMed  CAS  Google Scholar 

  3. BÜLOW, K.: Respiration and wakefulness in man. Acta phys. scand. 59, Suppl., 209 (1963).

    Google Scholar 

  4. BURT, R. A. P., BECKETT, A. H.: The absorption and excretion of pentazocine after administration by different routes. Brit. J. Anaesth. 43, 427 (1971).

    Article  PubMed  CAS  Google Scholar 

  5. CATCHLORE, R. F. H., KÄFER, E. R.: The effect of diazepam on the ventilatory response to carbon dioxide and on steady-state gas exchange. Anesthesiology 34, 9 (1971).

    Article  Google Scholar 

  6. CATCHLORE, R. F. H., KÄFER, E. R.: The effects of diazepam on respiration in patients with obstructive pulmonary disease. Anesthesiology 34, 14 (1971).

    Article  Google Scholar 

  7. CONWAY, C. M., ELLIS, D. B.:Propanidid. Brit. J. Anaesth. 42, 249 (1970).

    Article  PubMed  CAS  Google Scholar 

  8. CORSSEN, G., DEKORNFELD, Th. J.: Comparison of the respiratory depressant effects of fentanyl, fentanyl and dehydrobenzperidol, and morphine. Anesthesiology 27, 213 (1966).

    Article  Google Scholar 

  9. DALEN, E. J., EVANS, G. L., BANAS, J. S., BROOKS, H. L., PARASKOS, J. A., DEXTER, L.: The hemodynamic and respiratory effects of diazepam (Valium). Anesthesiology 30, 259 (1969).

    Article  PubMed  CAS  Google Scholar 

  10. DAVIES, D. R., DOUGHTY, A. G.: Premedication in children. A trial of intramuscular droperidol, droperidol-phenoperidine, papaveretumhyoscine and normal saline. Brit. J. Anaesth. 43, 65 (1971).

    Article  PubMed  CAS  Google Scholar 

  11. DAVIE, I., SCOTT, D. B., STEPHEN, G. W.: Respiratory effects of pentazocine and pethidine in patients anaesthetized with halothane and oxygen. Brit. J. Anaesth. 42, 113 (1970).

    Article  PubMed  CAS  Google Scholar 

  12. DAVIE, I. T., STEPHEN, G. W., SCOTT, D. B.: The effects of premedication with pentazocine and pethidine on respiration during general anaesthesia. Brit. J. Anaesth. 43, 500 (1971).

    Article  PubMed  CAS  Google Scholar 

  13. DOENICKE, A., MANNES, A.: Die Wechselwirkung von intravenösen Narkotika. Anaesthesiologie und Wiederbelebung 90, 236 (1975).

    CAS  Google Scholar 

  14. DOENICKE, A., SCHMIDINGER, St., KRUMEY, J.: Suxamethonium and serumcholinesterase. Comparative studies in vitro and in vivo on the catabolism of suxamethonium. Brit. J. Anaesth. 40, 834 (1968).

    Article  PubMed  CAS  Google Scholar 

  15. DOENICKE, A., WAGNER, E., BEETZ, K. H.: Blutgasanalysen (arteriell) nach drei kurzwirkenden i.v. Hypnotika. Anaesthesist 22, 353 (1973).

    PubMed  CAS  Google Scholar 

  16. DUNBAR, B. S., OVASSAPIAN, A., SMITH, Th. C.: The effects of methoxyflurane on Ventilation in man. Anesthesiology 28, 1020 (1967).

    Article  PubMed  CAS  Google Scholar 

  17. DUNDEE, J. W., HASLETT, H. K., KEILTY, S. R., PANDIT, S. K.: Studies of drugs given before anaesthesia. XX. Diazepam-containing mixtures. Brit. J. Anaesth. 42, 143 (1970).

    Article  PubMed  CAS  Google Scholar 

  18. DUNDEE, J. W., LOAN, W. B., MORRISON, J. D.: Studies of drugs given before anaesthesia. XIX. The opiates. Brit. J. Anaesth. 42, 54 (1970).

    CAS  Google Scholar 

  19. DUNDEE, J. W., MOORE, J., LOVE, W. J., NICHOLL, R. M., CLARKE, R. S. J.: Studies of drugs given before anaesthesia. VI. The phenothiazine derivates. Brit. J. Anaesth. 27, 332 (1965).

    Google Scholar 

  20. EVANS, J. M., HOGG, M. I. J., LUNN, J. N., ROSEN, M.: A comparative study of the narcotic agonist activity of naloxone and levallorphen. Anaesthesia 29, 721 (1974).

    Article  PubMed  CAS  Google Scholar 

  21. FISHMAN, J., HAHN, E. F., NORTON, B. I.: Comparative in vivo distribution of opiate agonists and antagonists by means of double isotope techniques. Life Sciences 17, 1119 (1975).

    Article  PubMed  CAS  Google Scholar 

  22. FORREST, W. H., BELLVILLE, J. W.: The effect of sleep plus morphine on the respiratory response to carbon dioxide. Anesthesiology 25, 137 (1964).

    Article  PubMed  Google Scholar 

  23. FOURDADE, H. E., STEVENS, W. C., LARSON, C. Ph., CROMWELL, Th. H., BAHLMAN, S. H., HICKEY, R. F., ITALSEY, M. J., EGER, E. I.: The ventilatory effects of forane, a new inhaled anesthetic. Anesthesiology 35, 26 (1971).

    Article  Google Scholar 

  24. FRY, D. E., WHITWAM, J. G., CHAKRABART, M. K.: Induction apnoea and the peripheral chemoreceptors. Brit. J. Anaesth. 45, 1054 (1973).

    Article  PubMed  CAS  Google Scholar 

  25. GASSER, J. C., BELLVILLE, J. W.: Interaction of the effects of hydroxyzine and pentazocine on human respiration. Anesthesiology 43, 599 (1975).

    Article  PubMed  CAS  Google Scholar 

  26. GASSER, J. C., BELLVILLE, J. W.: Die isolierte und kombinierte Wirkung von Doxapram und Pentazocine auf die Atmung. Anaesthesist 24, 526 (1975).

    PubMed  CAS  Google Scholar 

  27. GEISLER, L. S., ROST, H. D., VOGEL, F.: Doppelblindstudie über das Verhalten der Atmung nach intravenöser Verabreichung von Tilidin und Pentazocin. Prakt. Anästh. 10, 81 (1975).

    CAS  Google Scholar 

  28. GÖTZ, E., SCHOLZ, R.: Stoffwechselwirkungen von Ethrane und Halothan in der isolierten perfundierten Rattenleber. In: Ethrane -First European Symposium on Modern Anesthetic Agents (eds. P. LAWIN, R. BEER). Anaesthesiologie und Wiederbelebung, Bd. 84, p. 28. Berlin-Heidelberg-New York: Springer 1974.

    Google Scholar 

  29. GOLD, M. I., REICHENBERG, S., FREEMAN, E.: Respiratory depression in the sedated bronchitic patient. Anesthesiology 30, 492 (1969).

    Article  PubMed  CAS  Google Scholar 

  30. GOODWIN, N. M., BROCK-UTNE, J. G., DOWING, J. W., COLEMAN, A. J.: Benzoctamine. A preliminary report on a new sedative drug. Anaesthesia 29, 715 (1974).

    Article  PubMed  CAS  Google Scholar 

  31. GUPKA, P. K., DUNDEE, J. W. : Alterations in response to somatic pain associated with anaesthesia. XXII. Nikethamide, doxapram and naloxone. Brit. J. Anaesth. 45, 497 (1973).

    Article  Google Scholar 

  32. GUPKA, P. K., DUNDEE, J. W. : Morphine combined with doxapram or naloxone. Anaesthesia 29, 33 (1974).

    Article  Google Scholar 

  33. HALL, G. M., WHITWAM, J. G., MORGAN, M.: Some respiratory effects of Althesin. Brit. J. Anaesth. 45, 629 (1973).

    Article  PubMed  CAS  Google Scholar 

  34. HARRIS, R. A., MUNROE, J., FARMER, B., KIM, K. C., JENKINS, P.: Action of halothane upon mitochondrial respiration. Arch. Biochem. Biophysics 142, 435 (1971).

    Article  CAS  Google Scholar 

  35. HEINONEN, J., MUITTARI, A.: The effect of diazepam on airway resistance in asthmatics. Anaesthesia 27, 37 (1972).

    Article  PubMed  CAS  Google Scholar 

  36. HEITMANN, H. B., DRECHSEL, U., HERPFER, G., ZINDLER, M.: Die Wirkung von Piritramid (DipidolorR) auf die Regulation der Atmung und die orthostatische Stabilität des Kreislaufs. Anaesthesist 19, 152 (1970).

    PubMed  CAS  Google Scholar 

  37. HELLEWELL, J.: Induction of anaesthesia with diazepam. In: Diazepam in Anaesthesia, p. 47. Bristol: John Wright 1968.

    Google Scholar 

  38. HEMPELMANN, G., HEMPELMANN, W., KAHLSTORF, J., PIEPENBROCK, S.: Erfahrungen mit dem neuen Steroid-Anaestheticum CT-1341. Anaesthesist 22, 142 (1973).

    PubMed  CAS  Google Scholar 

  39. HIRSHMAN, C. A., McCULLOUGH, R. E., COHEN, P. J., WEIL, J. V.: Hypoxie ventilatory drive in dogs during thiopental, ketamine, or pentobarbital anesthesia. Anesthesiology 43, 628 (1975).

    Article  PubMed  CAS  Google Scholar 

  40. HIRSHMAN, C. A., MCCULLOUGH, R. E., COHEN, P. J., WEIL, J. V.: Effect of pentobarbitone on hypoxic ventilatory drive in man. Brit. J. Anaesth. 47, 963 (1975).

    Article  PubMed  CAS  Google Scholar 

  41. HOFFMAN, J. C., SMITH, Th. C.: The respiratory effects of meperidine and propiomazine in man. Anesthesiology. 32, 325 (1970).

    Article  PubMed  CAS  Google Scholar 

  42. HUNTER, A. R.: Diazepam (ValiumR) as a muscle relaxant during general anaesthesia: a pilot study. Brit. J. Anaesth. 39, 633 (1967).

    Article  Google Scholar 

  43. HUSE, K., HARTUNG, E., NADJMABADI, M. H.: Wirkungen von Naloxone (NarcanR) auf Kreislauf und Atmung nach Neurolept-Anaesthesie für neurochirurgische Operationen. Anaesthesist 23, 493 (1974).

    PubMed  CAS  Google Scholar 

  44. JENNETT, S., BARKER, J. G., FORREST, J. B.: A double-blind controlled study of the effects on respiration of pentazocine, phenoperidine and morphine in normal man. Brit. J. Anaesth. 40, 864 (1968).

    Article  PubMed  CAS  Google Scholar 

  45. KALLOS, T., SMITH, T. C.: The respiratory effects of Innovar given for premedication. Brit. J. Ariaesth. 41, 303 (1969).

    Article  CAS  Google Scholar 

  46. KNOLL, J., KOMLOS, E., TARDOS, L.: Über die Rolle der Eiweißbindung im Synergismus der Analgetica und Parasympathicomimetica. Acta physiol. hung. 4, 131 (1955).

    Google Scholar 

  47. KNOX, J. W. D., BOVILL, J. G., CLARKE, R. S. J., DUNDEE, J. W.: Clinical studies of induction agents. XXXVI. Ketamine. Brit. J. Anaesth. 42, 875 (1970).

    Article  CAS  Google Scholar 

  48. KUBICKI, St.: EEG-Veränderungen durch Neuroleptanalgesie. In: Fortschritte der Neuroleptanalgesie (ed. M. GEMPERLE). Anaesthesiologie und Wiederbelebung, Bd. 18, p. 39. Berlin-Heidelberg-New York: Springer 1966.

    Google Scholar 

  49. LARSON, C. Ph., EGER, E. I., MUALLEM, M., BUECHEL, D. R., MUNSON, E. S., EISELE, J. H.: The effects of diethyl ether and methoxyflurane on Ventilation: II. A comparative study in man. Anesthesiology 30, 174 (1969).

    Article  PubMed  CAS  Google Scholar 

  50. MARKELLO, R., KING, B. D.: Effects of propiomazine on respiration and circulation. Anesthesiology 21, 20 (1966).

    Article  Google Scholar 

  51. MATTHER, L. E., LINDOP, M. J., TUCKER, G. T., PFLUG, A. E.: Pethidine revisited: plasma concentrations and effects after intramuscular injections. Brit. J. Anaesth. 47, 1269 (1975).

    Article  Google Scholar 

  52. MATTHEW, H., PROODFOOT, A. T., AITKEN, R. C. B., RAEBURN, J. A., WRIGHT, N.: Nitrazepam - a safe hypnotic. Brit. med. J. 3, 177 (1969).

    Google Scholar 

  53. MORRISON, J. D.: Studies of drugs given before anaesthesia. XXII. Phenoperidine and fentanyl, alone and in combination with droperidol. Brit. J. Anaesth. 42, 1119 (1970).

    Article  PubMed  CAS  Google Scholar 

  54. MOSTERT, J. W., EVERS, J. L., HOBIKA, G. H., MOORE, R. H., AMBRUS, J. L.: Cardiovascular effects of anaesthesia with morphine or fentanyl in chronic renal failure and cerebral toxicity after morphine. Brit. J. Anaesth. 43, 1053 (1971).

    Article  PubMed  CAS  Google Scholar 

  55. MUNSON, E. S., LARSON, C. PH., BABAD, A. A., REGAN, M. J., BUECHEL, D. R., EGER, E. I.: The effects of halothane, fluroxene and cyclopropane on Ventilation: a comparative study in man. Anesthesiology 27, 716 (1966).

    Article  PubMed  CAS  Google Scholar 

  56. PEARCE, C.: A clinical trial of Ro 5-4200 (flunitrazepam) used to Supplement spinal anaesthesia in elderly patients. Brit. J. Anaesth. 46, 877 (1974).

    Article  PubMed  CAS  Google Scholar 

  57. PEARCE, C.: The respiratory effects of diazepam supplementation of spinal anaesthesia in elderly patients. Brit. J. Anaesth. 46, 439 (1974).

    Article  PubMed  CAS  Google Scholar 

  58. PERT, C. B., SNYDER, S. H.: Identification of opiate receptor binding in intact animal. Life Sciences 16, 1623 (1974).

    Article  Google Scholar 

  59. PICHLMAYR, J.: Klinische Untersuchungen über Hydroxyzin (MasmoranR) zur Operationsvorbereitung alter Patienten. Anaesthesist 19, 181 (1970).

    PubMed  CAS  Google Scholar 

  60. POTTER, D. R., PAYNE, J. P.: Newer analgetics: with special reference to pentazocine. Brit. J. Anaesth. 42, 186 (1970).

    Article  PubMed  CAS  Google Scholar 

  61. RAVIN, M. B.: Effect of postural variations on anatomic dead Space before and after atropine. Anesthesiology 27, 224 (1966).

    Article  Google Scholar 

  62. RIFAT, K., STAINIER, H., GEMPERLE, M., SZAPPANYOS, G., HEMMER, M., WEISS, V.: Klinische Untersuchungen des Steroid-Anaestheticums CT-1341 (AlthesinR). Anaesthesist 24, 6 (1975).

    PubMed  CAS  Google Scholar 

  63. Rigas, S. C.: Severe respiratory depression after pentazocine administration: two case reports (Correspondence). Brit. J. Anaesth. 42, 547 (1970).

    Article  PubMed  CAS  Google Scholar 

  64. RITZOW, H.: Über den atemdepressorischen Effekt von Morphin und Fentanyl und seine Beeinflußbarkeit durch Morphinantagonisten. Anaesthesist 22, 425 (1973).

    PubMed  CAS  Google Scholar 

  65. SAMUEL, I. O., DUNDEE, J. W.: Clinical studies of induction agents. XLII. Influence of injection rate and dosage on the induction complications with Althesin. Brit. J. Anaesth. 45, 1215 (1973).

    Article  PubMed  CAS  Google Scholar 

  66. SAVEGE, T. M., BLOGG, C. E., FOLEY, E. I., ROSS, L., LANG, M., SIMPSON, B. R.: The cardiorespiratory effects of Althesin and Ketamine. Anaesthesia 28, 391 (1973).

    Article  PubMed  CAS  Google Scholar 

  67. SCHOLZ, R., SCHWARZ, F., BÜCHER, Th.: Barbiturate und energieliefernder Stoffwechsel in der hämoglobindurchströmten Leber der Ratte. Z. Klin. Chem. 4, 179 (1966).

    CAS  Google Scholar 

  68. SMITH, Th. C., STEPHEN, G. W., ZEIGER, L., WOLLMAN, H.: Effects of premedicant drugs on respiration and gas exchange in man. Anesthesiology 23, 883 (1967).

    Article  Google Scholar 

  69. STOVNER, J., ENDRESEN, R.: Intravenous anaesthesia with diazepam. Acta anaesth. scand., Proc. II (Suppl.) 24, 223 (1966).

    Article  CAS  Google Scholar 

  70. TAMMISTO, T., TAKKI, S., TIGERSTEDT, I., KAUSTE, A.: A comparison of Althesin and Thiopentone in induction of anaesthesia. Brit. J. Anaesth. 45, 100 (1973).

    Article  PubMed  CAS  Google Scholar 

  71. TARHAN, S., MOFFIT, E. A., LUNDBORG, R. O., FRYE, R. L.: Hemodynamic and blood-gas effects of Innovar in patients with acquired heart disease. Anesthesiology 34, 250 (1971).

    Article  PubMed  CAS  Google Scholar 

  72. TILLEMENT, J. P.: Bases pharmacologiques des notions de synergie, d’antagonisme et de potentialisation. Rapport du XXe Congrès national d’Anesthésie - Réanimation, Strasbourg 1970.

    Google Scholar 

  73. UTTING, H. J., PLEUVRY, B. J.: Benzoctamine - a study of the respiratory effects of oral doses in human volunteers and interactions with morphine in mice. Brit. J. Anaesth. 47, 987 (1975).

    Article  PubMed  CAS  Google Scholar 

  74. VOGEL, W., BURCHARDI, H.: Der Einfluß verschiedener Analgetika (Pethidin, Pentazocin und Piritramid) auf Atmung und Kreislauf. Z. prakt. Anästh. 7, 69 (1972).

    CAS  Google Scholar 

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Doenicke, A., Grote, B. (1976). Pharmakologische Effekte und Wechselwirkungen von Prämedikationsund Narkosemitteln auf die Atmung. In: Ahnefeld, F.W., Bergmann, H., Burri, C., Dick, W., Halmàgyi, M., Rügheimer, E. (eds) Der Risikopatient in der Anästhesie. Klinische Anästhesiologie und Intensivtherapie, vol 12. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-66553-0_8

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  • DOI: https://doi.org/10.1007/978-3-642-66553-0_8

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