Advertisement

Pharmakologische Effekte und Wechselwirkungen von Prämedikationsund Narkosemitteln auf die Atmung

  • A. Doenicke
  • B. Grote
Part of the Klinische Anästhesiologie und Intensivtherapie book series (KAI, volume 12)

Zusammenfassung

Beschränken wir das Thema auf die klinisch zu erfassenden und meßbaren Parameter “Ventilation und Blutgase”, so könnten die pharmakologischen Effekte der in Frage kommenden Arzneimittel in Form tabellarischer Übersichten wiedergegeben werden.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Literatur

  1. 1.
    BELLVILLE, J. W., HOWLAND, W. S., SEED, J. C., HOODE, R. W.: The effect of sleep on the respiratory response to carbon dioxide. Anesthesiology 20, 628 (1959).PubMedCrossRefGoogle Scholar
  2. 2.
    BERKOWITZ, B. A., ASLING, J. H., SHNIDER, S. M., WAY, E. L.: Relationship of pentazocine plasma levels to pharmacological activity in man. Clin. Pharmacol. Ther. 10, 320 (1969).PubMedGoogle Scholar
  3. 3.
    BÜLOW, K.: Respiration and wakefulness in man. Acta phys. scand. 59, Suppl., 209 (1963).Google Scholar
  4. 4.
    BURT, R. A. P., BECKETT, A. H.: The absorption and excretion of pentazocine after administration by different routes. Brit. J. Anaesth. 43, 427 (1971).PubMedCrossRefGoogle Scholar
  5. 5.
    CATCHLORE, R. F. H., KÄFER, E. R.: The effect of diazepam on the ventilatory response to carbon dioxide and on steady-state gas exchange. Anesthesiology 34, 9 (1971).CrossRefGoogle Scholar
  6. 6.
    CATCHLORE, R. F. H., KÄFER, E. R.: The effects of diazepam on respiration in patients with obstructive pulmonary disease. Anesthesiology 34, 14 (1971).CrossRefGoogle Scholar
  7. 7.
    CONWAY, C. M., ELLIS, D. B.:Propanidid. Brit. J. Anaesth. 42, 249 (1970).PubMedCrossRefGoogle Scholar
  8. 8.
    CORSSEN, G., DEKORNFELD, Th. J.: Comparison of the respiratory depressant effects of fentanyl, fentanyl and dehydrobenzperidol, and morphine. Anesthesiology 27, 213 (1966).CrossRefGoogle Scholar
  9. 9.
    DALEN, E. J., EVANS, G. L., BANAS, J. S., BROOKS, H. L., PARASKOS, J. A., DEXTER, L.: The hemodynamic and respiratory effects of diazepam (Valium). Anesthesiology 30, 259 (1969).PubMedCrossRefGoogle Scholar
  10. 10.
    DAVIES, D. R., DOUGHTY, A. G.: Premedication in children. A trial of intramuscular droperidol, droperidol-phenoperidine, papaveretumhyoscine and normal saline. Brit. J. Anaesth. 43, 65 (1971).PubMedCrossRefGoogle Scholar
  11. 11.
    DAVIE, I., SCOTT, D. B., STEPHEN, G. W.: Respiratory effects of pentazocine and pethidine in patients anaesthetized with halothane and oxygen. Brit. J. Anaesth. 42, 113 (1970).PubMedCrossRefGoogle Scholar
  12. 12.
    DAVIE, I. T., STEPHEN, G. W., SCOTT, D. B.: The effects of premedication with pentazocine and pethidine on respiration during general anaesthesia. Brit. J. Anaesth. 43, 500 (1971).PubMedCrossRefGoogle Scholar
  13. 13.
    DOENICKE, A., MANNES, A.: Die Wechselwirkung von intravenösen Narkotika. Anaesthesiologie und Wiederbelebung 90, 236 (1975).Google Scholar
  14. 14.
    DOENICKE, A., SCHMIDINGER, St., KRUMEY, J.: Suxamethonium and serumcholinesterase. Comparative studies in vitro and in vivo on the catabolism of suxamethonium. Brit. J. Anaesth. 40, 834 (1968).PubMedCrossRefGoogle Scholar
  15. 15.
    DOENICKE, A., WAGNER, E., BEETZ, K. H.: Blutgasanalysen (arteriell) nach drei kurzwirkenden i.v. Hypnotika. Anaesthesist 22, 353 (1973).PubMedGoogle Scholar
  16. 16.
    DUNBAR, B. S., OVASSAPIAN, A., SMITH, Th. C.: The effects of methoxyflurane on Ventilation in man. Anesthesiology 28, 1020 (1967).PubMedCrossRefGoogle Scholar
  17. 17.
    DUNDEE, J. W., HASLETT, H. K., KEILTY, S. R., PANDIT, S. K.: Studies of drugs given before anaesthesia. XX. Diazepam-containing mixtures. Brit. J. Anaesth. 42, 143 (1970).PubMedCrossRefGoogle Scholar
  18. 18.
    DUNDEE, J. W., LOAN, W. B., MORRISON, J. D.: Studies of drugs given before anaesthesia. XIX. The opiates. Brit. J. Anaesth. 42, 54 (1970).Google Scholar
  19. 19.
    DUNDEE, J. W., MOORE, J., LOVE, W. J., NICHOLL, R. M., CLARKE, R. S. J.: Studies of drugs given before anaesthesia. VI. The phenothiazine derivates. Brit. J. Anaesth. 27, 332 (1965).Google Scholar
  20. 20.
    EVANS, J. M., HOGG, M. I. J., LUNN, J. N., ROSEN, M.: A comparative study of the narcotic agonist activity of naloxone and levallorphen. Anaesthesia 29, 721 (1974).PubMedCrossRefGoogle Scholar
  21. 21.
    FISHMAN, J., HAHN, E. F., NORTON, B. I.: Comparative in vivo distribution of opiate agonists and antagonists by means of double isotope techniques. Life Sciences 17, 1119 (1975).PubMedCrossRefGoogle Scholar
  22. 22.
    FORREST, W. H., BELLVILLE, J. W.: The effect of sleep plus morphine on the respiratory response to carbon dioxide. Anesthesiology 25, 137 (1964).PubMedCrossRefGoogle Scholar
  23. 23.
    FOURDADE, H. E., STEVENS, W. C., LARSON, C. Ph., CROMWELL, Th. H., BAHLMAN, S. H., HICKEY, R. F., ITALSEY, M. J., EGER, E. I.: The ventilatory effects of forane, a new inhaled anesthetic. Anesthesiology 35, 26 (1971).CrossRefGoogle Scholar
  24. 24.
    FRY, D. E., WHITWAM, J. G., CHAKRABART, M. K.: Induction apnoea and the peripheral chemoreceptors. Brit. J. Anaesth. 45, 1054 (1973).PubMedCrossRefGoogle Scholar
  25. 25.
    GASSER, J. C., BELLVILLE, J. W.: Interaction of the effects of hydroxyzine and pentazocine on human respiration. Anesthesiology 43, 599 (1975).PubMedCrossRefGoogle Scholar
  26. 26.
    GASSER, J. C., BELLVILLE, J. W.: Die isolierte und kombinierte Wirkung von Doxapram und Pentazocine auf die Atmung. Anaesthesist 24, 526 (1975).PubMedGoogle Scholar
  27. 27.
    GEISLER, L. S., ROST, H. D., VOGEL, F.: Doppelblindstudie über das Verhalten der Atmung nach intravenöser Verabreichung von Tilidin und Pentazocin. Prakt. Anästh. 10, 81 (1975).Google Scholar
  28. 28.
    GÖTZ, E., SCHOLZ, R.: Stoffwechselwirkungen von Ethrane und Halothan in der isolierten perfundierten Rattenleber. In: Ethrane -First European Symposium on Modern Anesthetic Agents (eds. P. LAWIN, R. BEER). Anaesthesiologie und Wiederbelebung, Bd. 84, p. 28. Berlin-Heidelberg-New York: Springer 1974.Google Scholar
  29. 29.
    GOLD, M. I., REICHENBERG, S., FREEMAN, E.: Respiratory depression in the sedated bronchitic patient. Anesthesiology 30, 492 (1969).PubMedCrossRefGoogle Scholar
  30. 30.
    GOODWIN, N. M., BROCK-UTNE, J. G., DOWING, J. W., COLEMAN, A. J.: Benzoctamine. A preliminary report on a new sedative drug. Anaesthesia 29, 715 (1974).PubMedCrossRefGoogle Scholar
  31. 31.
    GUPKA, P. K., DUNDEE, J. W. : Alterations in response to somatic pain associated with anaesthesia. XXII. Nikethamide, doxapram and naloxone. Brit. J. Anaesth. 45, 497 (1973).CrossRefGoogle Scholar
  32. 32.
    GUPKA, P. K., DUNDEE, J. W. : Morphine combined with doxapram or naloxone. Anaesthesia 29, 33 (1974).CrossRefGoogle Scholar
  33. 33.
    HALL, G. M., WHITWAM, J. G., MORGAN, M.: Some respiratory effects of Althesin. Brit. J. Anaesth. 45, 629 (1973).PubMedCrossRefGoogle Scholar
  34. 34.
    HARRIS, R. A., MUNROE, J., FARMER, B., KIM, K. C., JENKINS, P.: Action of halothane upon mitochondrial respiration. Arch. Biochem. Biophysics 142, 435 (1971).CrossRefGoogle Scholar
  35. 35.
    HEINONEN, J., MUITTARI, A.: The effect of diazepam on airway resistance in asthmatics. Anaesthesia 27, 37 (1972).PubMedCrossRefGoogle Scholar
  36. 36.
    HEITMANN, H. B., DRECHSEL, U., HERPFER, G., ZINDLER, M.: Die Wirkung von Piritramid (DipidolorR) auf die Regulation der Atmung und die orthostatische Stabilität des Kreislaufs. Anaesthesist 19, 152 (1970).PubMedGoogle Scholar
  37. 37.
    HELLEWELL, J.: Induction of anaesthesia with diazepam. In: Diazepam in Anaesthesia, p. 47. Bristol: John Wright 1968.Google Scholar
  38. 38.
    HEMPELMANN, G., HEMPELMANN, W., KAHLSTORF, J., PIEPENBROCK, S.: Erfahrungen mit dem neuen Steroid-Anaestheticum CT-1341. Anaesthesist 22, 142 (1973).PubMedGoogle Scholar
  39. 39.
    HIRSHMAN, C. A., McCULLOUGH, R. E., COHEN, P. J., WEIL, J. V.: Hypoxie ventilatory drive in dogs during thiopental, ketamine, or pentobarbital anesthesia. Anesthesiology 43, 628 (1975).PubMedCrossRefGoogle Scholar
  40. 40.
    HIRSHMAN, C. A., MCCULLOUGH, R. E., COHEN, P. J., WEIL, J. V.: Effect of pentobarbitone on hypoxic ventilatory drive in man. Brit. J. Anaesth. 47, 963 (1975).PubMedCrossRefGoogle Scholar
  41. 41.
    HOFFMAN, J. C., SMITH, Th. C.: The respiratory effects of meperidine and propiomazine in man. Anesthesiology. 32, 325 (1970).PubMedCrossRefGoogle Scholar
  42. 42.
    HUNTER, A. R.: Diazepam (ValiumR) as a muscle relaxant during general anaesthesia: a pilot study. Brit. J. Anaesth. 39, 633 (1967).CrossRefGoogle Scholar
  43. 43.
    HUSE, K., HARTUNG, E., NADJMABADI, M. H.: Wirkungen von Naloxone (NarcanR) auf Kreislauf und Atmung nach Neurolept-Anaesthesie für neurochirurgische Operationen. Anaesthesist 23, 493 (1974).PubMedGoogle Scholar
  44. 44.
    JENNETT, S., BARKER, J. G., FORREST, J. B.: A double-blind controlled study of the effects on respiration of pentazocine, phenoperidine and morphine in normal man. Brit. J. Anaesth. 40, 864 (1968).PubMedCrossRefGoogle Scholar
  45. 45.
    KALLOS, T., SMITH, T. C.: The respiratory effects of Innovar given for premedication. Brit. J. Ariaesth. 41, 303 (1969).CrossRefGoogle Scholar
  46. 46.
    KNOLL, J., KOMLOS, E., TARDOS, L.: Über die Rolle der Eiweißbindung im Synergismus der Analgetica und Parasympathicomimetica. Acta physiol. hung. 4, 131 (1955).Google Scholar
  47. 47.
    KNOX, J. W. D., BOVILL, J. G., CLARKE, R. S. J., DUNDEE, J. W.: Clinical studies of induction agents. XXXVI. Ketamine. Brit. J. Anaesth. 42, 875 (1970).CrossRefGoogle Scholar
  48. 48.
    KUBICKI, St.: EEG-Veränderungen durch Neuroleptanalgesie. In: Fortschritte der Neuroleptanalgesie (ed. M. GEMPERLE). Anaesthesiologie und Wiederbelebung, Bd. 18, p. 39. Berlin-Heidelberg-New York: Springer 1966.Google Scholar
  49. 49.
    LARSON, C. Ph., EGER, E. I., MUALLEM, M., BUECHEL, D. R., MUNSON, E. S., EISELE, J. H.: The effects of diethyl ether and methoxyflurane on Ventilation: II. A comparative study in man. Anesthesiology 30, 174 (1969).PubMedCrossRefGoogle Scholar
  50. 50.
    MARKELLO, R., KING, B. D.: Effects of propiomazine on respiration and circulation. Anesthesiology 21, 20 (1966).CrossRefGoogle Scholar
  51. 51.
    MATTHER, L. E., LINDOP, M. J., TUCKER, G. T., PFLUG, A. E.: Pethidine revisited: plasma concentrations and effects after intramuscular injections. Brit. J. Anaesth. 47, 1269 (1975).CrossRefGoogle Scholar
  52. 52.
    MATTHEW, H., PROODFOOT, A. T., AITKEN, R. C. B., RAEBURN, J. A., WRIGHT, N.: Nitrazepam - a safe hypnotic. Brit. med. J. 3, 177 (1969).Google Scholar
  53. 53.
    MORRISON, J. D.: Studies of drugs given before anaesthesia. XXII. Phenoperidine and fentanyl, alone and in combination with droperidol. Brit. J. Anaesth. 42, 1119 (1970).PubMedCrossRefGoogle Scholar
  54. 54.
    MOSTERT, J. W., EVERS, J. L., HOBIKA, G. H., MOORE, R. H., AMBRUS, J. L.: Cardiovascular effects of anaesthesia with morphine or fentanyl in chronic renal failure and cerebral toxicity after morphine. Brit. J. Anaesth. 43, 1053 (1971).PubMedCrossRefGoogle Scholar
  55. 55.
    MUNSON, E. S., LARSON, C. PH., BABAD, A. A., REGAN, M. J., BUECHEL, D. R., EGER, E. I.: The effects of halothane, fluroxene and cyclopropane on Ventilation: a comparative study in man. Anesthesiology 27, 716 (1966).PubMedCrossRefGoogle Scholar
  56. 56.
    PEARCE, C.: A clinical trial of Ro 5-4200 (flunitrazepam) used to Supplement spinal anaesthesia in elderly patients. Brit. J. Anaesth. 46, 877 (1974).PubMedCrossRefGoogle Scholar
  57. 57.
    PEARCE, C.: The respiratory effects of diazepam supplementation of spinal anaesthesia in elderly patients. Brit. J. Anaesth. 46, 439 (1974).PubMedCrossRefGoogle Scholar
  58. 58.
    PERT, C. B., SNYDER, S. H.: Identification of opiate receptor binding in intact animal. Life Sciences 16, 1623 (1974).CrossRefGoogle Scholar
  59. 59.
    PICHLMAYR, J.: Klinische Untersuchungen über Hydroxyzin (MasmoranR) zur Operationsvorbereitung alter Patienten. Anaesthesist 19, 181 (1970).PubMedGoogle Scholar
  60. 60.
    POTTER, D. R., PAYNE, J. P.: Newer analgetics: with special reference to pentazocine. Brit. J. Anaesth. 42, 186 (1970).PubMedCrossRefGoogle Scholar
  61. 61.
    RAVIN, M. B.: Effect of postural variations on anatomic dead Space before and after atropine. Anesthesiology 27, 224 (1966).CrossRefGoogle Scholar
  62. 62.
    RIFAT, K., STAINIER, H., GEMPERLE, M., SZAPPANYOS, G., HEMMER, M., WEISS, V.: Klinische Untersuchungen des Steroid-Anaestheticums CT-1341 (AlthesinR). Anaesthesist 24, 6 (1975).PubMedGoogle Scholar
  63. 63.
    Rigas, S. C.: Severe respiratory depression after pentazocine administration: two case reports (Correspondence). Brit. J. Anaesth. 42, 547 (1970).PubMedCrossRefGoogle Scholar
  64. 64.
    RITZOW, H.: Über den atemdepressorischen Effekt von Morphin und Fentanyl und seine Beeinflußbarkeit durch Morphinantagonisten. Anaesthesist 22, 425 (1973).PubMedGoogle Scholar
  65. 65.
    SAMUEL, I. O., DUNDEE, J. W.: Clinical studies of induction agents. XLII. Influence of injection rate and dosage on the induction complications with Althesin. Brit. J. Anaesth. 45, 1215 (1973).PubMedCrossRefGoogle Scholar
  66. 66.
    SAVEGE, T. M., BLOGG, C. E., FOLEY, E. I., ROSS, L., LANG, M., SIMPSON, B. R.: The cardiorespiratory effects of Althesin and Ketamine. Anaesthesia 28, 391 (1973).PubMedCrossRefGoogle Scholar
  67. 67.
    SCHOLZ, R., SCHWARZ, F., BÜCHER, Th.: Barbiturate und energieliefernder Stoffwechsel in der hämoglobindurchströmten Leber der Ratte. Z. Klin. Chem. 4, 179 (1966).Google Scholar
  68. 68.
    SMITH, Th. C., STEPHEN, G. W., ZEIGER, L., WOLLMAN, H.: Effects of premedicant drugs on respiration and gas exchange in man. Anesthesiology 23, 883 (1967).CrossRefGoogle Scholar
  69. 69.
    STOVNER, J., ENDRESEN, R.: Intravenous anaesthesia with diazepam. Acta anaesth. scand., Proc. II (Suppl.) 24, 223 (1966).CrossRefGoogle Scholar
  70. 70.
    TAMMISTO, T., TAKKI, S., TIGERSTEDT, I., KAUSTE, A.: A comparison of Althesin and Thiopentone in induction of anaesthesia. Brit. J. Anaesth. 45, 100 (1973).PubMedCrossRefGoogle Scholar
  71. 71.
    TARHAN, S., MOFFIT, E. A., LUNDBORG, R. O., FRYE, R. L.: Hemodynamic and blood-gas effects of Innovar in patients with acquired heart disease. Anesthesiology 34, 250 (1971).PubMedCrossRefGoogle Scholar
  72. 72.
    TILLEMENT, J. P.: Bases pharmacologiques des notions de synergie, d’antagonisme et de potentialisation. Rapport du XXe Congrès national d’Anesthésie - Réanimation, Strasbourg 1970.Google Scholar
  73. 73.
    UTTING, H. J., PLEUVRY, B. J.: Benzoctamine - a study of the respiratory effects of oral doses in human volunteers and interactions with morphine in mice. Brit. J. Anaesth. 47, 987 (1975).PubMedCrossRefGoogle Scholar
  74. 74.
    VOGEL, W., BURCHARDI, H.: Der Einfluß verschiedener Analgetika (Pethidin, Pentazocin und Piritramid) auf Atmung und Kreislauf. Z. prakt. Anästh. 7, 69 (1972).Google Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1976

Authors and Affiliations

  • A. Doenicke
  • B. Grote

There are no affiliations available

Personalised recommendations