Summary
Studies were carried out on 24 Macaca mulatta monkeys which were sacrificed from 6 h to 6 days following irradiation of one hemisphere. The ultrastructural changes of the vascular bed were observed. A number of points are made: (1) Edema involved a rise in pinocytosis of the endothelial cells of all vascular territories whereas the tight junctions between endothelial cells remained intact, (2) Distended perivascular spaces were found surrounding arterioles and venules, but seldom surrounding capillaries. These spaces probably are important for the formation and, above all, the resolution of edema.
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Cervós-Navarro, J., Christmann, U., Sasaki, S. (1976). An Ultrastructural Substrate for the Resolution of Post-Irradiation Brain Edema. In: Pappius, H.M., Feindel, W. (eds) Dynamics of Brain Edema. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-66524-0_9
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