Summary
Our studies have indicated that (1) micropinocytosis plays a major role in the increased permeability of the blood-brain barrier (BBB) during seizures, (2) seizure-induced hypertension causes most of the barrier breakdown and enhanced micropinocytosis, and (3) under these conditions there is no evidence of cerebral edema in the areas of obvious BBB breakdown.
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Petito, C.K., Schaefer, J.A., Plum, F. (1976). The Blood-Brain Barrier in Experimental Seizures. In: Pappius, H.M., Feindel, W. (eds) Dynamics of Brain Edema. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-66524-0_8
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DOI: https://doi.org/10.1007/978-3-642-66524-0_8
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