Summary
The freezing lesion used to induce cerebral edema leads to epileptic changes in the EEG probably unrelated to cerebral edema. This makes the freezing lesion inappropriate in studies to evaluate the EEG effects of cerebral edema.
Local cortical coagulation lesions produced cerebral edema without clinical or electrographic evidence of epilepsy.
Moderate amounts of cerebral edema of vasogenic variety do not produce delta activity in the EEG. With massive amounts of edema, delta activity was present, but was seen only in animals without a wide craniectomy. It was probably secondary to midbrain and diencephalic disturbances resulting from increased volume of the brain rigidly contained within the cranial cavity.
Cerebral edema has both clinical and electroencephalographic effects and monitoring these effects in experimental studies is feasible, although techniques of inducing very large amounts of edema without decompression of the brain would be necessary to consistently produce EEG and clinical changes.
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References
Clasen, R.A., Cooke, P.M., Martin, F.A., Williams, J.R., Hass, G.M.: Cerebral edema and electroencephalographic changes after local acute closed cerebral injury. Arch. Neurol. Psychiat. (Chicago) 80, 696–707 (1958)
Daly, D.D., Thomas, J.E.: Sequential alterations in the electroencephalograms of patients with brain tumors. Electroenceph. clin. Neurophysiol. 10, 395–404 (1958)
Gloor, P., Kalabay, O., Giard, N.: The electroencephalogram in diffuse encephalopathies: electroencephalographic correlates of grey and white matter lesions. Brain 91, 779–802 (1968)
Klatzo, I., Miguel, J., Otenasek, R.: The application of fluorescein labelled serum proteins (FLSP) to the study of vascular permeability in the brain. Acta neuropath. (Wien) 2, 144–160 (1962)
Knott, J.R., Ingram, W.R., Chiles, W.D.: Effect of subcortical lesions on cortical electroencephalograms in cats. Arch. Neurol. Psychiat. (Chicago) 73, 203–215 (1955)
Lewin, E.: The production of epileptogenic cortical foci in experimental animals by freezing. In: Experimental Models of Epilepsy. Purpura, D.P., (ed.). New York: Raven Press 1972, pp. 37–49
Nakamura, Y., Ohye, C.: Delta wave production in neocortical EEG by acute lesions within thalamus and hypothalamus of the cat. Electroenceph. clin. Neurophysiol. 20, 677–684 (1964)
Pappius, H.M., Wolfe, L.S.: Some further studies on vasogenic edema. This volume, pp. 138–143
Pappius, H.M., McCann, W.P.: Effects of steroids on cerebral edema in cats. Arch. Neurol. 20, 207–216 (1969)
Walter, W.G.: The location of cerebral tumors by electroencephalography. Lancet 231, 305–308 (1936)
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© 1976 Springer-Verlag Berlin · Heidelberg
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Schaul, N., Ball, G., Gloor, P., Pappius, H.M. (1976). The EEG in Cerebral Edema. In: Pappius, H.M., Feindel, W. (eds) Dynamics of Brain Edema. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-66524-0_24
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DOI: https://doi.org/10.1007/978-3-642-66524-0_24
Publisher Name: Springer, Berlin, Heidelberg
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